Clinical Effect and Immune Regulation of Yunpi Huatan Tongqiao Decoction Combined with Nasal Massage for Child Adenoid Hypertrophy

OBJECTIVE To study the clinical and immune regulation effects of Yunpi Huatan Tongqiao decoction combined with nasal massage for child adenoid hypertrophy (CAH). METHODS 90 CAH cases were randomly divided into the control group (Xinqin granules)， TCM internal treatment group (Yunpi Huatan Tongqiao Decoction)， and the TCM internal and external combined treatment group (Yunpi Huatan Tongqiao decoction combined with nasal massage). Clinical and immune regulation effects of Yunpi Huatan Tongqiao decoction in the treatment of CAH were evaluated. RESULTS In terms of the curative effect， the total effective rates in the TCM internal and external combined treatment group， TCM internal treatment group and the control group were 96.7%， 90.0% and 66.6%， respectively. In terms of TCM Syndrome curative effect， the total effective rates in the TCM internal and external combined treatment group， TCM internal treatment group and the control group were 96.7%， 93.3% and 76.7%， respectively. There were significant differences among three groups in clinical total effects and TCM syndromes (P<0.05，P<0.01). Improvements of nasal congestion， snoring， mouth-open breathing， sleep uneasiness， molars， impaired concentration， slow reaction and susceptibility (colds and bronchitis frequencies) in the TCM internal and external combined treatment group and the TCM internal treatment group were better than those in the control group (P<0.05， P<0.01). The curative effects of the TCM internal and external combined treatment group in improving mouth-open breathing and sleep uneasiness were better than those of the TCM internal treatment group (P<0.01). There were significant differences in accessory examination scores (nasopharyngeal lateral projection score) among three groups before and after the treatment (P<0.01). There were significant differences in accessory examination A/N values among three groups before and after the treatment (P<0.05)， the TCM internal and external combined treatment group and the TCM internal treatment group were better than that of the control group(P<0.05). There were significant differences in CD3+， CD8+ and CD4+/CD8+ in the TCM internal and external combined treatment group and the TCM internal treatment group before and after the treatment (P<0.01)， and P<0.05， compared with the control group. CONCLUSIONS Yunpi Huatan Tongqiao decoction combined with nasal massage works internally and externally， can improve the clinical effect of CAH， obviously improve the children's clinical symptoms， and also has a regulatory effect on cell immunity at the same time.