Self-made Xianxiong Mixture and Beiou Cataplasm Treating Reflux Esophagitis: 100 cases

OBJECTIVE To observe the clinical effects of Xianxiong Mixture and Beiou Cataplasm for treating reflux esophagitis (RE). METHODS 200 patients were randomized into treatment group (100 cases treated by Xianxiong Mixture and Beiou Cataplasm) and control group (100 cases treated by omeprazole). The treatment course for both groups are 8 weeks. The effects and integral changes of clinical symptoms， effects of gastroscope， RE grouping and integral evaluation under gastroscope， and relapse were compared before and after the treatment. RESULTS The total effective rate of the treatment group is 93% and control group 84%. There was significant difference between the two groups (P<0.05). The integral and total integral of each symptom in both groups all decreased. Compared with the condition before the treatment group， there was significant difference (P<0.05). After the treatment， significant difference exists in the symptom improvement of burning heart， reflux， retrosternal pain but no significant difference exists in the symptom improvement of dysphagia. The total effective rate of treatment group is 93% and control group 84% by gastroscope reexamination after 8 weeks. There was significant difference between the two groups (P<0.05). The gastroscope RE grading in both groups declined after the treatment. After administration of 6 months， the recurrence rate of treatment group is 5.56% and control group 30.43% and there was significant difference (P<0.05). CONCLUSION The therapeutic effects of Xianxiong Mixture and Beiou Cataplasm for treating RE is better than that of the control group. At the meanwhile， it has low recurrence rate and can enhance the life quality of the patients.