Effect of Lirukang Liquid on Morphology of Mammary Gland, Uterus and Ovary of Models with Hyperplasia of Mammary Glands

OBJECTIVE To investigate into the effect of Lirukang Liquid on the morphology of mammary gland, uterus and ovary of models with hyperplasia of mammary gland. METHOD Light microscope and image analyzer were used to calculate the area of cell glandular cavity, matrix and cell nucleus before and after drug administration, and the morphological changes in the uterus and ovary. RESULT (1) Lirukang Liquid had marked effect of dispersing and treating dilation of mammary gland cavity, matrix edema and enlargement of cell nucleus; (2) Lirukang Liquid could relieve the pathological changes in the uterus and ovary of the models. CONCLUSION In treating hyperplasia of mammary gland, Chinese drugs not only change the local pathological hyperplasia, but also improve the pathological morphology of the uterus and ovary, the mechanisms of which is probably due to the effect of regulating the function of hypothalamus - pituitary body - ovary gonad axis.