Protective Effect of Quyu Xiaoban Capsule on Endothelial Dysfunction of Patients with Artherosclerosis

OBJECTIVE To observe the effect of Quyu Xiaoban Capsule on blood lipid, nitrogen oxide (NO), endothelin 1 (ET - 1) and the function of endothelium in patients with artherosclerosis (AS). METHOD 80 patients were divided randomly into an experiment group and a control group, who were given ultrasonic examination on endothelium function and determination of the levels of blood lipid, NO and ET - 1. RESULT After the treatment, the levels of TC and LDL - C in the experiment group dropped markedly, with LDL- C level significantly lower than the control group. In the experiment group, NO level rose compared with the control group and ET - 1 level dropped markedly ( P < 0.05) . CONCLUSION Quyu Xiaoban Capsule can markedly reduce blood lipid level, prevent NO/ET - 1 imbalance and improve the diastole function of dependent blood vessels.