Abstract: OBJECTIVE To study the clinical effect of scraping therapy along meridian combined with loratadine in the treatment of persistent allergic rhinitis (PAR) caused by heat accumulation in lung meridian. METHODS Sixty patients with PAR caused by heat accumulation in lung meridian included in the affiliated hospital of Nanjing University of Chinese Medicine from March， 2015 to September， 2016 were selected and randomly divided into the loratadine control group， the scraping and loratadine combination group， 30 cases in each group. Patients in both groups were treated for 4 weeks. Clinical curative effect was evaluated by total nasal symptoms scores (TNSS)， visual analog scale (VAS)， RQLQ score， total IgE， IL-4 level and total effective rate. RESULTS TNNS， VAS， RQLQ score， total IgE and IL-4 level all decreased in two groups after 4 weeks' treatment (P<0.01). The treatment group was better than the control group in improving VAS， RQLQ score and IL-4 level (P<0.01). And the treatment group was better than the control group in clinical effect and long-term follow-up effect (P<0.05~0.01). CONCLUSIONS Scraping and loratadine combination therapy is an effective treatment for allergic rhinitis and has satisfied long-term effect.