Abstract: It is believed that stagnant heat is an important cause of wasting-thirst， and an important factor that influencing the development and changes of wasting-thirst. In the course of wasting-thirst， stagnant heat， as an independent pathogenic factor， runs through the disease. The understanding of the causes of the stagnant heat syndrome of wasting-thirst believes that consumption of five zang-organs is the main cause of the disease， and internal damage caused by the seven emotions and endogenous five pathogenic factors are important pathogenic factors of the disease. The pathogenesis of the disease takes the deficiency of liver and kidney as the root factors， dampness， phlegm and blood stasis as the superficial factors. The treatment must give the consideration to both blood stasis and heat， and the combination of cooling blood and dissipating blood stasis is the key for treatment of the disease.