Abstract: OBJECTIVE To investigate the relationship between clinical symptoms and the corresponding drugs of hypertension. METHODS The relationships of symptoms and drugs in 1493 hypertension cases were analyzed correspondingly. RESULTS The relationships of symptoms and drugs in hypertension cases were as follows， the corresponding drugs treating syndrome of hyperactivity of yang due to yin deficiency mainly were: Herba Taxilli， Fructus Corni， Rhizoma Alismatis， Cortex Eucommiae， Rhizoma Dioscoreae; the corresponding drugs treating syndrome of static blood blocking collaterals mainly were Radix Puerariae Lobatae， Flos Cartham，Rhizoma Chuanxiong， Semen Persicae， Radix et Rhizoma Salviae Miltiorrhizae， Radix Paeoniae Rubr， Radix et Rhizoma Glycyrrhizae; the corresponding drugs treating phlegm dampness and blood stasis mainly were Caulis Bambusae in Taenia， Rhizoma Pinelliae， Pericarpium Citri Reticulatae， Rhizoma Acori Tatarinowii， Rhizoma Atractylodis Macrocephalae， Poria; the corresponding drugs treating qi and blood deficiency syndrome mainly were Radix Angelicae Sinensis，Radix Astragali，Radix Codonopsis，Radix Paeoniae Alba; the corresponding drugs treating hyperactivity of liver fire syndrome mainly were Radix Rehmanniae，Radix et Rhizoma Gentianae，Spica Prunellae，Fructus Gardeniae，Radix Scutellariae，Flos Chrysanthemi. CONCLUTION This study analyzed the relationship of symptoms and drugs in hypertension correspondingly and offered clinical bases for hypertension's Chinese medicine differentiation.