太子参药材中环肽A、B含量分析及其动态研究

邹立思, 傅兴圣, 刘训红, 巢建国, 谷巍, 马阳, 侯娅, 李艳蓉

邹立思, 傅兴圣, 刘训红, 巢建国, 谷巍, 马阳, 侯娅, 李艳蓉. 太子参药材中环肽A、B含量分析及其动态研究[J]. 南京中医药大学学报, 2013, 29(2): 175-178.
引用本文: 邹立思, 傅兴圣, 刘训红, 巢建国, 谷巍, 马阳, 侯娅, 李艳蓉. 太子参药材中环肽A、B含量分析及其动态研究[J]. 南京中医药大学学报, 2013, 29(2): 175-178.
ZOU Li-si, FU Xin-sheng, LIU Xun-hong, CHAO Jian-guo, GU Wei, MA Yang, HOU Ya, LI Yan-rong. Study on the Dynamic Change of Heterophyllin A and B in Radix Pseudostellariae[J]. Journal of Nanjing University of traditional Chinese Medicine, 2013, 29(2): 175-178.
Citation: ZOU Li-si, FU Xin-sheng, LIU Xun-hong, CHAO Jian-guo, GU Wei, MA Yang, HOU Ya, LI Yan-rong. Study on the Dynamic Change of Heterophyllin A and B in Radix Pseudostellariae[J]. Journal of Nanjing University of traditional Chinese Medicine, 2013, 29(2): 175-178.

太子参药材中环肽A、B含量分析及其动态研究

Study on the Dynamic Change of Heterophyllin A and B in Radix Pseudostellariae

  • 摘要: 目的 分析不同产区、地域及采收时间太子参中环肽A(HA)、B(HB)含量变化,为探索太子参药材品质形成过程提供基础资料。方法 用高效液相色谱法同时测定太子参中HA、HB含量。结果 不同产区、同一产区不同地域及不同采收时间太子参中HA、HB的含量存在差异,HA、HB的动态积累具有一定规律。结论 不同产区太子参中HA、HB的含量及其比值具有差异相关性,太子参中HA、HB的最高积累总值时间段与传统采收期基本一致。
    Abstract: OBJECTIVE To analyze the content changes of heterophyllin A (HA) and B (HB) in Radix Pseudostellariae from different habitats, regions and harvest time, and to provide the basic information for exploring the quality forming process of Radix Pseudostellariae.METHODS The content of HA and HB was determined by RP-HPLC.RESULTS The contents of HA and HB in Radix Pseudostellariae from different habitats, regions and harvest time were variable. Dynamic change of HA and HB in Radix Pseudostellariae in different harvest time showed a regular pattern.CONCLUSION There are correlative differences between the content and the ratio of HA and HB in Radix Pseudostellariae from different habitats. The total amount of HA and HB is the highest in the traditional harvest time.
  • [1] 国家药典委员会.中华人民共和国药典:一部[S]. 北京:化学工业出版社, 2010:67.
    [2] ChPC. Pharmacopoeia Commission of the People's Republic of China: Volume 1[S]. Beijing: Chemical industry press, 2010: 67.
    [3] 谭宁华,周俊.太子参中新环肽-太子参环肽C[J].云南植物研究,1995, 17(1):60.
    [4] Tan NH, Zhou J. A new cyclopeptied from pseudostellaria heterophylla[J]. Acta botanica Yunnanica, 1995, 17(1): 60.
    [5] 丁中涛,周俊,谭宁华,等.石竹科植物环肽研究进展[J].化学研究与应用,1999, 11(5):492-494.
    [6] Ding ZT, Zhou J, Tan NH, et al.Progress in chemistry of cyclic peptides from plants of caryophyllaceae[J]. Chemic Res Applic, 1999, 11(5): 492-494.
    [7] 刘训红,阚毓铭,王玉玺.太子参多糖的研究[J].中草药,1993, 24(3):119-121.
    [8] Liu XG, Kan YM, Wang YX. Study on polysaccharides from pseudostellaria heterophylla[J]. Chin Tradit Herb Drugs, 1993, 24(3): 119-121.
    [9] 李滢,杨秀伟.太子参(柘荣1号)的化学成分研究[J].中国中药杂志,2008, 33(20):2353-2355.
    [10] Li Y, Yang XW.Studies on chemical constituents of root tuber of cultivated Pseudostellaria heterophylla (Zheshen No.1)[J]. Chin J Chin Mater Med, 2008, 33(20): 2353-2355.
    [11] 王喆星,徐绥绪,张国刚,等.太子参化学成分的研究(IV)[J].中国药物化学杂志,1992, 2(3):65-67.
    [12] Wang ZX, Xu SX, Zhang GG, et al.Study on the chemical constituents of pseudotellaria heterophylla (MIQ.)[J]. Chin J Med Chem, 1992, 2(3): 65-67.
    [13] 王玉玺,刘训红,李汉宝,等.太子参补益作用机理的探讨[J].南京部队医药,1992(5):21-22.
    [14] Wang YX, Liu XG, Li HB, et al.Discussion on enrishing mechanism of pseudotellaria heterophylla[J]. Nanjing Army Med, 1992(5): 21-22.
    [15] Sheng R, Xu X, Tang Q, et al. Polysaccharide of radix pseudostellariae improves chronic fatigue syndrome induced by poly I:C in mice[J]. Evid Based Complement Alternat Med, 2011(4): 840516.
    [16] 刘训红,陈彬,王玉玺.太子参多糖抗应激和免疫增强作用实验研究[J].江苏中医,2000, 21(10):51-57.
    [17] Liu XG, Chen B, Wang YX.Experimental study of stress resistance and immune enhancement effect of pseudostellaria polysaccharide[J]. Jiangsu J Tradit Chin Med, 2000, 21(10): 51-57.
    [18] 刘维俊,黄光才,叶小青,等.太子参胶囊的药效学研究[J].中药新药与临床药理,1994, 5(3):51,58.
    [19] Liu WJ, Huang GC, Ye XQ, et al.Study on the pharmacodynamics of pseudostellaria heterophylla capsule[J]. Tradit Chin Drug Res Clin Pharm, 1994, 5(3): 51,58.
    [20] 刘训红,陈彬,王玉玺.太子参总皂苷药理作用的初步研究[J].江苏药学与临床研究,2000, 8(3):6-8.
    [21] Liu XG, Chen B, Wang YX.Preliminary Studies on Pharmacological Action of Total Saponins from Radix Pseudostellariae[J]. Jiangsu Pharm Clin Res, 2000, 8(3): 6-8.
    [22] 倪受东,夏伦祝,徐先祥,等.太子参多糖对四氧嘧啶糖尿病小鼠的治疗作用[J].安徽医药,2010, 14(5):521-522.
    [23] NI SD, XIA LZ, XU XX, et al. Effect of pseudostellaria polysaccharides in diabetic mice by alloxan[J]. Anhui Med Pharm J, 2010, 14(5): 521-522.
    [24] 杨亚滨,谭宁华,许文彦,等.中药太子参中环肽A和B含量测定的HPLC方法研究[J].云南中医学院学报,2009, 32(6):33-36.
    [25] YANG YB, TAN NH,XU WY, et al. Content determination of heterophyllin a and B in pseudostellaria heterophylla by HPLC methods[J]. J Yunnan Univer Tradit Chin Med, 2009, 32(6): 33-36.
    [26] 刘训红,韩乐,王丽娟,等.太子参药材质量标准研究[J].中国药房,2010, 21(19):1769-1771.
    [27] Liu XG, Han L, Wang LJ, et al.Study on Quality Standards of Pseudostellaria heterophylla[J]. Chin Pharm, 2010, 21(19): 1769-1771.
计量
  • 文章访问数:  675
  • HTML全文浏览量:  8
  • PDF下载量:  730
  • 被引次数: 0
出版历程
  • 收稿日期:  2012-12-10
  • 修回日期:  2013-02-15
  • 刊出日期:  2013-03-09

目录

    /

    返回文章
    返回