Volume 36 Issue 6
Nov.  2020
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Article Navigation >  Journal of Nanjing University of traditional Chinese Medicine  > 2020  >  36(6): 921-925
LYUZhi-zhen, KONGLing-jun, YAOChong-jie, GUOGuang-xin, ZHOUXin, ZHANGShuai-pan, FANGMin. Discussion on the Selection and Application of Animal Models of Low Back Pain Based on Chinese Manipulation Analgesia[J]. Journal of Nanjing University of traditional Chinese Medicine, 2020, 36(6): 921-925.
Citation: LYUZhi-zhen, KONGLing-jun, YAOChong-jie, GUOGuang-xin, ZHOUXin, ZHANGShuai-pan, FANGMin. Discussion on the Selection and Application of Animal Models of Low Back Pain Based on Chinese Manipulation Analgesia[J]. Journal of Nanjing University of traditional Chinese Medicine, 2020, 36(6): 921-925.
shu

Discussion on the Selection and Application of Animal Models of Low Back Pain Based on Chinese Manipulation Analgesia

  • 1.

    Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, 200437, China

  • 2.

    Research Institute of Tuina, Shanghai Academy of Traditional Chinese Medicine, Shanghai, 200437, China

  • 3.

    College of Acumox and Tuina, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, China

  • Publish Date: 2020-11-10
    Abstract
  • Low back pain (LBP) is one of the common clinical symptoms in waist diseases. The research on the analgesia of low back pain by Chinese manipulation has made good achievements in recent years， providing a basis for studying the analgesic mechanism of Chinese manipulation treatment of low back pain and exploring scientific research methods. Currently， several animal models have been applied to low back pain research，mainly including neuropathic pain and chronic inflammation pain such as CCD， SNL， ELFS， and adjuvant injection model.The author compared and analyzed four animal models of low back pain， and summarized the characteristics of the modeling methods and clinical application， in order to provide reference for future experimental research.

     

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    • References(28)
  • [1]
    SPIJKER-HUIGES A， GROENHOF F， WINTERS JC， et al. Radiating low back pain in general practice: Incidence， prevalence， diagnosis， and long-term clinical course of illness[J]. Scand J Prim Heal Care， 2015， 33(1): 27-32.
    [2]
    WALKER BF. The prevalence of low back pain: A systematic review of the literature from 1966 to 1998[J]. J Spinal Disord， 2000， 13(3): 205-217.
    [3]
    LOISEL P. Cost-benefit and cost-effectiveness analysis of a disability prevention model for back pain management: A six year follow up study[J]. Occup Environ Med， 2002， 59(12): 807-815.
    [4]
    SHMAGEL A， FOLEY R， IBRAHIM H. Epidemiology of chronic low back pain in US adults: Data from the 2009-2010 national health and nutrition examination survey[J]. Arthritis Care Res， 2016， 68(11): 1688-1694.
    [5]
    YANG M， FENG Y， PEI H， et al. Effectiveness of Chinese massage therapy (Tui Na) for chronic low back pain: Study protocol for a randomized controlled trial[J]. Trials， 2014， 15: 418.
    [6]
    JIANG S， ZHANG H， FANG M， et al. Analgesic effects of ChineseTuina massage in a rat model of pain[J]. Exp Ther Med， 2016， 11(4): 1367-1374.
    [7]
    李赫桐， 勾禹， 田发明， 等. 腰痛相关动物模型的研究进展[J]. 中国实验动物学报， 2019， 27(3): 399-404.
    [8]
    严广斌. 神经病理性疼痛[J]. 中华关节外科杂志(电子版)， 2017， 11(4): 446.
    [9]
    HU SJ， XING JL. An experimental model for chronic compression of dorsal root ganglion produced by intervertebral foramenStenosis in the rat[J]. Pain， 1998， 77(1): 15-23.
    [10]
    SONG XJ， HU SJ， GREENQUIST KW， et al. Mechanical and thermal hyperalgesia and ectopic neuronal discharge after chronic compression of dorsal root Ganglia[J]. J Neurophysiol， 1999， 82(6): 3347-3358.
    [11]
    林志刚， 蒋诗超， 程艳彬， 等. 推拿对腰椎间盘突出症大鼠DRG神经元P2X3受体影响的实验研究[J]. 中华中医药学刊， 2017， 35(10): 2475-2479.
    [12]
    SONG P， SUN W， ZHANG H， et al. Possible mechanism underlying analgesic effect ofTuina in rats may involve piezo mechanosensitive channels within dorsal root Ganglia axon[J]. J Tradit Chin Med， 2018， 38(6): 834-841.
    [13]
    金小高， 罗爱林， 张广雄. 三种大鼠神经病理性疼痛模型的制备和效果比较[J]. 临床麻醉学杂志， 2005， 21(5): 338-340.
    [14]
    BENNETT GJ， XIE YK. A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man[J]. Pain， 1988， 33(1): 87-107.
    [15]
    SUN HK， JIN MC. An experimental model for peripheral neuropathy produced by segmental spinal nerve ligation in the rat[J]. Pain， 1992， 50(3): 355-363.
    [16]
    王江栓， 李变锋. 大鼠脊神经选择性结扎镜像痛模型的筛选建立[J]. 中国医学创新， 2014， 11(18): 30-32.
    [17]
    吴志伟， 宋朋飞， 朱清广， 等. 神经病理性疼痛动物模型研究进展[J]. 中华中医药学刊， 2019， 37(5): 1083-1087.
    [18]
    邓敏倩. 脊髓背角自噬对大鼠神经病理性疼痛的影响及推拿的镇痛机制研究[D]. 南宁: 广西医科大学， 2019.
    [19]
    TANEJA A， DELLA PASQUA O， DANHOF M. Challenges in translational drug research in neuropathic and inflammatory pain: The prerequisites for a new paradigm[J]. Eur J Clin Pharmacol， 2017， 73(10): 1219-1236.
    [20]
    HENDERSON CNR， CRAMER GD， ZHANG Q， et al. Introducing the external link model for studying spine fixation and misalignment: Part 2， biomechanical features[J]. J Manip Physiol Ther， 2007， 30(4): 279-294.
    [21]
    GATTERMAN MI．Foundations of Chiropractic-subluxation(second edition)[M]. Philadelphia：Elsevier's Health Sciences Rights Department，2005:31-33.
    [22]
    孔令军， 房敏， 詹红生， 等. 大鼠腰椎亚脱位模型刚度及其脊髓前角尼氏小体变化研究[J]. 中华中医药杂志， 2012， 27(12): 3234-3237.
    [23]
    REN K， DUBNER R. Inflammatory models of pain and hyperalgesia[J]. ILAR J， 1999， 40(3): 111-118.
    [24]
    程艳彬. 基于IB4阳性伤害性感受器探讨推拿手法镇痛效应机理的研究[D]. 上海: 上海中医药大学， 2016.
    [25]
    GATTERMAN MI. Foundations of Chiropractic Subluxation[M]. 2nd edit. Missouri: Elsevier Mosby，2005:246-247．
    [26]
    KAIGLE AM， POPE MH， FLEMING BC， et al. A method for the intravital measurement of interspinous kinematics[J]. J Biomech， 1992， 25(4): 451-456.
    [27]
    孔令军， 程英武， 詹红生， 等. 大鼠腰椎亚脱位模型节段活动范围减小的研究[J]. 中国骨伤， 2012， 25(3): 241-245.
    [28]
    TONG L，PRIETO GA，COTMAN CW. IL-1β suppresses cLTP-induced surface expression of GluA1 and actin polymerization via ceramide-mediated Src activation[J]. J Neuroinflammation，2018，15(1):127.
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