Citation: | XIALing, GUOSheng, QIANDa-wei, WUWen-xing, BUFan-shu, ZHUYue, ZHAOMing, NIUYang, DUANJin-ao. Exploration on the Mechanism of Bazhen Yizhi Prescription in Treating Alzheimer's Disease Based on Network Pharmacology and Molecular Docking[J]. Journal of Nanjing University of traditional Chinese Medicine, 2020, 36(6): 876-881. |
[1] |
RAJASEKHAR K,GOVINDARAJU T.Current progress,challenges and future prospects of diagnostic and therapeutic interventions in Alzheimer's disease[J].RSC Adv,2018,8(42):23780-23804.
|
[2] |
ZENDEHBAD AS,NOROOZIAN M,SHAKIBA A,et al.Validation of iranian smell identification test for screening of mild cognitive impairment and Alzheimer's disease[J/OL].Appl Neuropsychol Adult[2020-09-20].https://www.tandfonline.com/doi/abs/10.1080/23279095.2019.1710508?journalCode=hapn21.
|
[3] |
王莉, 王虎, 黄翰宇, 等. 阿尔茨海默病发病机制的研究进展[J]. 中国老年学杂志, 2017, 37(19): 4953-4954.
|
[4] |
HUSNA IBRAHIM N,YAHAYA MF,MOHAMED W,et al.Pharmacotherapy of Alzheimer's disease:seeking clarity in a time of uncertainty[J].Front Pharmacol,2020,11:261.
|
[5] |
牛阳, 张霞, 王荣, 等. 八珍益智颗粒提取工艺研究[J]. 西北药学杂志, 2012, 27(4): 294-296.
|
[6] |
冉玉兵,刘磊,张瑞芬,等.龙眼果肉提取物改善SAMP8小鼠学习记忆功能[J].现代食品科技,2017,33(6):1-8.
|
[7] |
钟灵,王振富.山药多糖对老年性痴呆小鼠抗氧化能力的影响[J].中国应用生理学杂志,2015,31(1):42-43,48.
|
[8] |
郭曼萍, 赵俊男, 施伟丽, 等. 益智仁改善认知障碍的研究进展[J]. 中西医结合心脑血管病杂志, 2019, 17(18): 2778-2783.
|
[9] |
SHI WT,ZHONG J,ZHANG Q,et al.Structural characterization and antineuroinflammatory activity of a novel heteropolysaccharide obtained from the fruits of Alpinia oxyphylla[J].Carbohydr Polym,2020,229:115405.
|
[10] |
徐煜彬,徐志立,李明玉,等.茯苓及其化学拆分组分学习记忆及镇静催眠的性味药理学研究[J].中草药,2014,45(11):1577-1584.
|
[11] |
LIU CX,LIU R,FAN HR,et al.Network pharmacology bridges traditional application and modern development of traditional Chinese medicine[J].Chin Herb Med,2015,7(1):3-17.
|
[12] |
宗阳,丁美林,贾可可,等.基于网络药理学和分子对接法探寻达原饮治疗新型冠状病毒肺炎(COVID-19)活性化合物的研究[J].中草药,2020,51(4):836-844.
|
[13] |
ZAPLATIC E,BULE M,SHAH SZA,et al.Molecular mechanisms underlying protective role of quercetin in attenuating Alzheimer's disease[J].Life Sci,2019,224:109-119.
|
[14] |
文琪.益智提取物活性多成分在大鼠体内药代动力学研究[D].海口:海南医学院,2018.
|
[15] |
马俊俏.益智仁挥发油对学习记忆障碍小鼠的改善作用及机制研究[D].武汉:湖北中医药大学,2019.
|
[16] |
马俊俏,吴勇,周俊璇,等.益智仁挥发油对东莨菪碱致小鼠学习记忆障碍的改善作用研究[J].中国药房,2018,29(22):3074-3078.
|
[17] |
冯星,王正濂,林永成,等.双白术内酯对Aβ1-40致痴呆模型大鼠的作用[J].中国药理学通报,2009,25(7):949-951.
|
[18] |
CHOI GN,KIM JH,KWAK JH,et al.Effect of quercetin on learning and memory performance in ICR mice under neurotoxic trimethyltin exposure[J].Food Chem,2012,132(2):1019-1024.
|
[19] |
KARIMIPOUR M,RAHBARGHAZI R,TAYEFI H,et al.Quercetin promotes learning and memory performance concomitantly with neural stem/progenitor cell proliferation and neurogenesis in the adult rat dentate gyrus[J].Int J Dev Neurosci,2019,74:18-26.
|
[20] |
QI Y,GUO L,JIANG YB,et al.Brain delivery of quercetin-loaded exosomes improved cognitive function in AD mice by inhibiting phosphorylated tau-mediated neurofibrillary tangles[J].Drug Deliv,2020,27(1):745-755.
|
[21] |
李伟瀚,程笑,杨滢霖,等.山柰酚通过抑制神经炎症及保护血脑屏障而改善大鼠脑缺血再灌注神经功能[J].中国药理学与毒理学杂志,2019,33(9):673.
|
[22] |
KHAJEVAND-KHAZAEI MR,ZIAEE P,MOTEVVALIZADEH SA,et al.Naringenin ameliorates learning and memory impairment following systemic lipopolysaccharide challenge in the rat[J].Eur J Pharmacol,2018,826:114-122.
|
[23] |
王琳,金桂芳,余河汉,等.p38MAPK信号通路抗阿尔茨海默病的研究进展[J].医学综述,2019,25(24):4834-4839.
|
[24] |
汲广全.白术有效成分对巨噬细胞和树突状细胞免疫活性的研究[D].广州:华南理工大学,2014.
|