Volume 35 Issue 2
Mar.  2019
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Article Navigation >  Journal of Nanjing University of traditional Chinese Medicine  > 2019  >  35(2): 234-240
TAOWei-wei, DONGYu, LIULi, XIAODong, WUHao-ran, WUHao-xing, CHENGang, DILiu-qing, WANGHan-qing. Research Progress on the Effect of Intestinal Flora on Depression Based on 'Brain-Gut' Axis[J]. Journal of Nanjing University of traditional Chinese Medicine, 2019, 35(2): 234-240.
Citation: TAOWei-wei, DONGYu, LIULi, XIAODong, WUHao-ran, WUHao-xing, CHENGang, DILiu-qing, WANGHan-qing. Research Progress on the Effect of Intestinal Flora on Depression Based on "Brain-Gut" Axis[J]. Journal of Nanjing University of traditional Chinese Medicine, 2019, 35(2): 234-240.
shu

Research Progress on the Effect of Intestinal Flora on Depression Based on "Brain-Gut" Axis

  • 1.

    Key Laboratory for Encephalopathy of Chinese Medicine, School of Basic Medicine, Nanjing University of Chinese Medicine, Nanjing, 210023, China

  • 2.

    School of Pharmacy, Nanjingl University of Chinese Medicine, Nanjing, 210023, China

  • 3.

    School of Pharmacy, Ningxia Medical University, Yinchuan, 750004, China

  • Publish Date: 2019-03-10
    Abstract
  • In recent years， with the deepening of the research on the regulation of intestinal flora， the "brain-gut" axis， which is used to describe the complex network relationship between gastrointestinal microflora and their hosts. It is a bidirectional information regulation pathway based on the presence of intestinal flora in mammals and plays an important role in human health and disease process. Depression is a long and recurring chronic mental illness that differs from simple mood disorders. Studies have shown that intestinal flora can significantly influence host stress response， anxiety， depression and cognitive function through the brain-gut axis. Based on the intestinal flora， this paper reviewed the research status and mechanism of depression， aiming to provide basis and reference for the treatment of depression.

     

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