Citation: | YUANLu, LIANGBo-zhi, LUOJian-hua, LULi-na, YANGHui, LILi, YANGDong-hua. Effect and Mechanism of Leonurine on Rats with Ventricular Remodeling Induced by Isoproterenol[J]. Journal of Nanjing University of traditional Chinese Medicine, 2019, 35(2): 180-184. |
[1] |
AZEVEDO PS, POLEGATO BF, MINICUCCI MF, et al. Cardiac remodeling: Concepts, clinical impact, pathophysiological mechanisms and pharmacologic treatment[J]. Arq Bras Cardiol, 2016,106(1): 62-69.
|
[2] |
ZHU YZ, WU W, ZHU Q, et al. Discovery of Leonuri and therapeutical applications: From bench to bedside[J].Pharmacol Ther, 2018, 188:26-35.
|
[3] |
梁赵文,罗建华,杨冬花,等.益母草碱对慢性心力衰竭心肌重构大鼠心房利钠肽、血管紧张素Ⅱ影响的研究[J].贵州医药,2016,40(12):1235-1238.
|
[4] |
NGUYEN MN, KIRIAZIS H, GAO XM, et al. Cardiac fibrosis and arrhythmo-genesis[J].Compr Physiol, 2017, 7(3):1009-1049.
|
[5] |
张勇涛,蒋凡.生理性和病理性心肌肥厚的信号传导机制[J].中华心血管病杂志,2015,43(3):277-280.
|
[6] |
MA Y, ZOU H, ZHU XX, et al. Transforming growth factor β: A potential biomarker and therapeutic target of ventricular remodeling[J]. Oncotarget, 2017,8(32): 53780-53790.
|
[7] |
KONG P, CHRISTIA P, FRANGOGIANNIS NG.The pathogenesis of cardiac fibrosis[J].Cell Mol Life Sci, 2014,71(4):549-574.
|
[8] |
宋冰,丁利.硫化氢抑制p38MAPK和NF-κB p65信号通路活性改善糖尿病心肌纤维化的作用和机制[J]. 解放军医学杂志,2016,41(11):902-907.
|
[9] |
ARABACILAR P, MARBER M. The case for inhibiting p38 mitogen-activated protein kinase in heart failure[J].Front Pharmacol, 2015, 6:102.
|
[10] |
DAVENPORT AP, HYNDMAN KA, DHAUN N, et al. Endothelin[J]. Pharmacol Rev, 2016, 68(2): 357-418.
|
[11] |
JEN HL, LIU PL, CHEN YH, et al. Peroxisome proliferator-activated receptorα reduces endothelin-1-caused cardiomyocyte hypertrophy by inhibiting nuclear factor-κB and adiponectin[J]. Mediators Inflamm, 2016, 2016: 5609121.
|
[12] |
WENG X, YU L, LIANG P, et al. A crosstalk between chromatin remodeling and histone H3K4 methyltransferase complexes in endothelial cells regulates angiotensin Ⅱ-induced cardiac hypertrophy[J]. J Mol Cell Cardiol, 2015,82: 48-58.
|
[13] |
GONG X, MING X, DENG P, et al. Mechanisms regulating the nuclear translocation of p38 MAP kinase[J]. J Cell Biochem, 2010,110(6):1420-1429.
|
[14] |
CHEN X, GAO B, PONNUSAMY M, et al. MEF2 signaling and human diseases[J]. Oncotarget, 2017, 8(67):112152-112165.
|
[15] |
ZHAO M, NEW L, KRAVCHENKO VV, et al. Regulation of the MEF2 family of transcription factors by p38[J]. Mol Cell Biol,1999,19(1):21-30.
|
[16] |
HAN J, JIANG Y, LI Z, et al. Activation of the transcription factor MEF2C by the MAP kinase p38 in inflammation[J]. Nature,1997,386(6622):296-299.
|
[17] |
DADSON K, TURDI S, HASHEMI S, et al. Adiponectin is required for cardiac MEF2 activation during pressure overload induced hypertrophy[J]. J Mol Cell Cardiol, 2015, 86:102-109.
|