| Citation: | YU Man-shu, SHI Jun, ZHAO Jun-yi, ZHU Yi-lin, SHENG Mei-xiao. The Inhibitory Effect of Astragaloside Ⅳ on Epithelial Mesenchymal Transition of Human Peritoneal Mesothelial Cells by Regulating Akt Signaling[J]. Journal of Nanjing University of traditional Chinese Medicine, 2019, 35(1): 53-57.
|
| [1] |
MEHROTRA R， DEVUYST O， DAVIES SJ， et al. The current state of peritoneal dialysis[J]. J Am Soc Nephrol， 2016， 27: 3238-3252.
|
| [2] |
YAEZ-MO M， LARA-PEZZI E， SELGAS R， et al. Peritoneal dialysis and epithelial-to-mesenchymal transition of mesothelial cells[J]. N Engl J Med， 2003， 348(5): 403-413.
|
| [3] |
史俊， 俞曼殊， 盛梅笑，等. 黄芪甲苷抑制高糖腹透液诱导HMrSV5氧化应激与EMT的实验研究[J]. 南京中医药大学学报， 2016， 32(4): 337-341.
|
| [4] |
YOSHIZAWA H， MORISHITA Y， WATANABE M， et al. TGF-β 1-siRNA delivery with nanoparticles inhibits peritoneal fibrosis[J]. Gene Ther， 2015， 22(4): 333.
|
| [5] |
HUANG TS， LI L， MOALIM‐NOUR L， et al. A regulatory network involving β‐Catenin， E-cadherin， PI3k/Akt， and Slug balances self‐renewal and differentiation of human pluripotent stem cells in response to wnt signaling[J]. Stem Cell， 2015， 33(5): 1419-1433.
|
| [6] |
ZHOU D， TAN RJ， FU H， et al. Wnt/β-catenin signaling in kidney injury and repair: a double-edged sword[J]. Lab Invest， 2016， 96(2): 156-167.
|
| [7] |
BAO Z， XU X， LIU Y， et al. CBX7 negatively regulates migration and invasion in glioma via Wnt/β-catenin pathway inactivation[J]. Oncotarget， 2017， 8(24): 39048-39063.
|
| [8] |
GUO Y， GUPTE M， UMBARKAR P， et al. Entanglement of GSK-3β， β-catenin and TGF-β1 signaling network to regulate myocardial fibrosis[J]. J Mol Cell Cardiol， 2017， 110: 109.
|
| [9] |
LIEN EC， LYSSIOTIS CA， CANTLEY LC. Metabolic reprogramming by the PI3K-Akt-mTOR pathway in cancer[J]. Metab Cancer， 2016:39-72.
|
| [10] |
MATSUMOTO T， YOKOI A， HASHIMURA M， et al. TGF-β-mediated LEFTY/Akt/GSK-3β/Snail axis modulates epithelial-mesenchymal transition and cancer stem cell properties in ovarian clear cell carcinomas[J]. Mol Carcinogen， 2018， 57(8):957-967.
|
| [11] |
YU D， LEI JQ， GUO SL， et al. The CNPY2 enhances epithelial-mesenchymal transition via activating the AKT/GSK3β pathway in non-small cell lung cancer[J]. Cell Biol Int， 2018， 42(8):959-964.
|
| [12] |
BACHELDER RE， YOON SO， FRANCI C， et al. Glycogen synthase kinase-3 is an endogenous inhibitor of Snail transcription: implications for the epithelial mesenchymal transition[J]. J Cell Biol， 2005， 168(1): 29-33.
|
| [13] |
WANG H， ZHANG G， ZHANG H， et al. Acquisition of epithelial–mesenchymal transition phenotype and cancer stem cell-like properties in cisplatin-resistant lung cancer cells through AKT/β-catenin/Snail signaling pathway[J]. Eur J Pharmacol， 2014， 723: 156-166.
|
| [14] |
WU K， FAN J， ZHANG L， et al. PI3K/Akt to GSK3β/β-catenin signaling cascade coordinates cell colonization for bladder cancer bone metastasis through regulating ZEB1 transcription[J]. Cell Signal， 2012， 24(12): 2273-2282.
|
| [15] |
WALKER NM， BELLOLI EA， STUCKEY L， et al. Mechanistic target of rapamycin complex 1 (mTORC1) and mTORC2 as key signaling intermediates in mesenchymal cell activation[J]. J Biol Chem， 2016， 291(12): 6262-6271.
|
| [16] |
LAMOUILLE S， CONNOLLY E， SMYTH JW， et al. TGF-β-induced activation of mTOR complex 2 drives epithelial-mesenchymal transition and cell invasion[J]. J Cell Sci， 2012， 125(5): 1259-1273.
|
| [17] |
HAN Q， LIN L， ZHAO B， et al. Inhibition of mTOR ameliorates bleomycin-induced pulmonary fibrosis by regulating epithelial-mesenchymal transition[J]. Biochem Bioph Res Comm， 2018， 500(4): 839-845.
|
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