Volume 34 Issue 6
Nov.  2018
Turn off MathJax
Article Contents
Article Navigation >  Journal of Nanjing University of traditional Chinese Medicine  > 2018  >  34(6): 639-644
ZOUJia-yu, RENShu-jing, DUANYan-bing, CHENRui, CHENZhi-peng. Advances in Research on Hydrogels Derived from Traditional Chinese Medicine with the Characteristics of 'Unification of Medicines and Excipients'[J]. Journal of Nanjing University of traditional Chinese Medicine, 2018, 34(6): 639-644.
Citation: ZOUJia-yu, RENShu-jing, DUANYan-bing, CHENRui, CHENZhi-peng. Advances in Research on Hydrogels Derived from Traditional Chinese Medicine with the Characteristics of "Unification of Medicines and Excipients"[J]. Journal of Nanjing University of traditional Chinese Medicine, 2018, 34(6): 639-644.
shu

Advances in Research on Hydrogels Derived from Traditional Chinese Medicine with the Characteristics of "Unification of Medicines and Excipients"

  • 1.

    School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, 210023, China

  • 2.

    Nanjing Xinbai Pharmaceutical Company, Nanjing, 210038, China

  • Publish Date: 2018-11-10
    Abstract
  • There are a wide range of sources of Chinese medicinal materials， and some of them have a shaping function in pharmaceutics while exerting pharmacological effects， which is called “unification of medicines and excipient”. We consulted the domestic and foreign literatures in recent years and summarized several hydrogels derived from traditional Chinese medicine with this function. Finally， we trace their research progress and hope to provide the basement for the research and development of pharmaceutics in traditional Chinese medicine in future.

     

    • FullText(HTML)
  • loading
    • References(53)
  • [1]
    朱丹溪.丹溪治法心要[M].北京:人民卫生出版社，1983:21.
    [2]
    胡濙.卫生易简方[M].北京:人民卫生出版社，1984:6.
    [3]
    郑俊民.药用辅料手册[M].北京:化学工业出版社，2005:5-20.
    [4]
    张定堃，傅超美，林俊芝，等.中药制剂的“药辅合一”及其应用价值[J].中草药，2017，48(10):1921-1929.
    [5]
    RIBEIRO-RAMA AC，FIGUEIREDO IV， VEIGA FJ， et al. Hepatic and renal toxicities of indomethacin acid， salt form and complexed forms with hydroxypropyl-β-cyclodextrin on wistar rats after oral administration[J]. Fundament Clin Pharmacol， 2011， 25(5):599-607.
    [6]
    BUWALDA SJ， BOERE KW， DIJKSTRA PJ， et al. Hydrogels in a historical perspective: from simple networks to smart materials[J]. J Controll Release， 2014， 190(10):254-273.
    [7]
    YANG L， LIANG G， ZHANG Z， et al. Sodium alginate/Na+ -rectorite composite films: Preparation， characterization and properties[J]. J Appl Polym Sci， 2009， 114(2):1235-1240.
    [8]
    PRESTWICH GD. Hyaluronic acid-based clinical biomaterials derived for cell and molecule delivery in regenerative medicine[J]. J Controll Release， 2011，155(2):193-199.
    [9]
    LEE Y， JIN WB， DONG HO， et al. In situ forming gelatin-based tissue adhesives and their phenolic content-driven properties[J]. J Mater Chem B， 2013， 1(18):2407-2414.
    [10]
    GUPTA S， PRAMANIK AK， KAILATH A， et al. Composition dependent structural modulations in transparent poly(vinyl alcohol)hydrogels[J]. Colloids Surf B Biointerfaces， 2009，74:186-190.
    [11]
    QIAN HE. Aloe vera: A valuable ingredient for the food， pharmaceutical and cosmetic industries: A review[J]. Critical Rev Food Sci Nutrit， 2004， 44(2):91-96.
    [12]
    YIN JY， NIE SP， LI J， et al. Mechanism of interactions between calcium and viscous polysaccharide from the seeds of Plantago asiatica L[J]. J Agric Food Chem， 2012， 60(32):7981-7987.
    [13]
    CHEN W， WYK BEV， VERMAAK I， et al. Cape aloes: A review of the phytochemistry， pharmacology and commercialisation of Aloe ferox[J]. Phytochem Lett， 2012， 5(1):1-12.
    [14]
    FINBERG MJ， MUNTINGH GL， VAN RENSBURG CE. A comparison of the leaf gel extracts of Aloe ferox and Aloe vera in the topical treatment of atopic dermatitis in Balb/c mice.[J]. Inflammopharmacology， 2015， 23(6):337-341.
    [15]
    HAASBROEK A. Drug absorption enhancement capacities and mechanisms of action of Aloe vera gel materials[D]. Potchefstroom Campus: North-West University， 2018.
    [16]
    AVIJGAN M， KAMRAN A， ABEDINI A. Effectiveness of aloe vera gel in chronic ulcers in comparison with conventional treatments[J]. Iranian J Med Sci， 2016， 41(3):S30-S30.
    [17]
    BALAN BJ， NIEMCEWICZ M， KOCIK J， et al. Oral administration of Aloe vera gel， anti-microbial and anti-inflammatory herbal remedy， stimulates cell-mediated immunity and antibody production in a mouse model[J]. Centr-Europ J Immunol， 2014， 39(2):125-130.
    [18]
    CHIHARA T， SHIMPO K， KANEKO T， et al. Dietary aloe vera gel powder and extract inhibit azoxymethane-induced colorectal aberrant crypt foci in mice fed a high-fat diet[J]. Asian Pac J Cancer Prev， 2015， 16(2):683-687.
    [19]
    MANSOUR G， OUDA S， SHAKER A， et al. Clinical efficacy of new aloe vera- and myrrh-based oral mucoadhesive gels in the management of minor recurrent aphthous stomatitis: a randomized， double-blind， vehicle-controlled study[J]. J Oral Pathol Med， 2014， 43(6): 405-409.
    [20]
    THOMAS A， HARDING KG， MOORE K. Alginates from wound dressing active human macrophages to secrete tumor necrosis factor[J]. Biomaterials， 2000， 21: 1797-1802.
    [21]
    ROWE RC， SHESKEY PJ， OWEN SC， et al. Handbook of Pharmaceutical Excipients[M]. London: Pharmaceutical press， 2006:544.
    [22]
    LEE KY， MOONEY DJ. Alginate: properties and biomedical applications[J]. Progr Polym Sci， 2012， 37(1):106.
    [23]
    EI-SHERBINY IM， ABDEL-MOGIB M， DAWIDAR AAM， et al. Biodegradable pH-responsive Alginate-poly (lactic-co-glycolic acid) nano/micro hydrogel matrices for oral delivery of sylimarin[M]. Carbohydr Polym， 2011， 83: 1345-1354.
    [24]
    VENKATESAN J， LOWE B， ANIL S， et al. Seaweed polysaccharides and their potential biomedical applications[J]. Starch-Starke， 2015， 67(5/6):381-390.
    [25]
    DEVI DA， SMITHA B， SRIDHAR S， et al. Pervaporation separation of isopropanol/water mixtures through crosslinked chitosan membranes[J]. J Membr Sci， 2005， 262(1/2):91-99.
    [26]
    ANSORENA E， DE BP， UCAKAR B， et al. Injectable alginate hydrogel loaded with GDNF promotes functional recovery in a hemisection model of spinal cord injury.[J]. Inter J Pharmaceut， 2013， 455(1/2):148-158.
    [27]
    XU G， CHENG L， ZHANG Q， et al. In situ thiolated alginate hydrogel: Instant formation and its application in hemostasis[J]. J Biomater Appl， 2016，31(5):721.
    [28]
    GONG R， LI C， ZHU S， et al. A novel pH sensitive hydrogel based on dual cross-linked Alginate/N-glutaric acid chitosan for oral delivery of protein[J]. Carbohydr Polym， 2011， 85：869-874.
    [29]
    韩淑芬，金仲品.没药的药理活性研究进展[J].时珍国医国药， 2008， 19(6):1502-1503.
    [30]
    崔锐， 周金云. 乳香化学和药理的研究进展[J]. 中国药学杂志， 2003， 38(6):407-410.
    [31]
    叶建红. 对药乳香没药的药理作用与临床应用体会[J]. 中医药临床杂志， 2003， 15(3):264-265.
    [32]
    徐央波， 柴欣楼. 活络效灵丹组成及临床应用的研究进展[J]. 辽宁中医杂志， 2013(8):1717-1719.
    [33]
    XIAO N， SUHAIL MM， YANG Q， et al. Frankincense essential oil prepared from hydrodistillation of Boswellia sacra gum resins induces human pancreatic cancer cell death in cultures and in a xenograft murine model[J]. BMC Compl Alternat Med， 2012， 12(1):1-14.
    [34]
    TAUSCH L， HENKEL A， SIEMONEIT U， et al. Identification of human cathepsin G as a functional target of boswellic acids from the anti-inflammatory remedy frankincense.[J]. J Immunol， 2009， 183(5):3433.
    [35]
    TAUSCH L， HENKEL A U. Identification of human cathepsin G as a functional target of boswellic acids from the anti-inflammatory remedy frankincense.[J]. J Immunol， 2009， 183(5):3433.
    [36]
    FRANK MB， YANG Q， OSBAN J， et al. Frankincense oil derived from Boswellia carteri induces tumor cell specific cytotoxicity[J]. BMC Compl Alternat Med， 2009， 9(1):6.
    [37]
    TIPTON DA， LYLE B， BABICH H， et al. In vitro cytotoxic and anti-inflammatory effects of myrrh oil on human gingival fibroblasts and epithelial cells[J]. Toxicol In Vitro， 2003， 17(3):301-310.
    [38]
    HAFFOR AS. Effect of myrrh (Commiphora molmol) on leukocyte levels before and during healing from gastric ulcer or skin injury[J].J Immunotoxicol， 2010， 7(1):68-75.
    [39]
    BAQUE MA， MOH SH， LEE EJ， et al. Production of biomass and useful compounds from adventitious roots of high-value added medicinal plants using bioreactor[J]. Biotechnol Adv， 2012， 30(6):1255-1267.
    [40]
    王世荣. 葛根的药理作用及研究进展[J]. 中外女性健康研究， 2015(15):8-9.
    [41]
    尹乐斌， 夏秋良， 赵良忠，等. 葛根药理作用研究进展[J]. 现代农业科技， 2016(4):68-69.
    [42]
    OU C， ZHANG J， ZHANG X， et al. Phenothiazine as an aromatic capping group to construct a short peptide-based 'super gelator'[J]. Chem Communicat， 2013， 49(18):1853-1855.
    [43]
    张建武. 葛根素水凝胶在MSCs移植治疗心肌梗死中的作用及机制研究[D]. 广州：南方医科大学， 2016.
    [44]
    ZHOU YX， ZHANG H， PENG C. Puerarin: a review of pharmacological effects[J]. Phytother Res， 2014， 28(7):961-975.
    [45]
    ZHANG S， CHEN S， SHEN Y， et al. Puerarin induces angiogenesis in myocardium of rat with myocardial infarction[J]. Biol Pharm Bull， 2006， 29(5):945-950.
    [46]
    王军， 王春宏， 任晓玲，等. 白及胶的临床应用[J]. 中国医院药学杂志， 2004， 24(9):556-557.
    [47]
    宋璟璐，王龙，韩凤娟.白及作为抗肿瘤药物的回顾性分析[J].中医药信息，2013， 30(3):148-150.
    [48]
    卓微伟.中药白及的药理作用及临床应用的研究进展[J].北方药学， 2014(11):69.
    [49]
    徐花荣.白及多糖的提取分离及其在中药水凝胶巴布剂型中的应用[D].西安：西北大学， 2006.
    [50]
    张少园.白及多糖超多孔水凝胶的制备及其性能研究[D].长春：吉林大学，2017.
    [51]
    WANG C， SUN J， LUO Y， et al. A polysaccharide isolated from the medicinal herb Bletilla striata induces endothelial cells proliferation and vascular endothelial growth factor expression in vitro.[J]. Biotechnol Lett， 2006， 28(8):539-543.
    [52]
    DIAO H， LI X， CHEN J， et al. Bletilla striata polysaccharide stimulates inducible nitric oxide synthase and proinflammatory cytokine expression in macrophages[J]. J Biosci Bioengineer， 2008， 105(2):85.
    [53]
    DONG L， XIA S， LUO Y， et al. Targeting delivery oligonucleotide into macrophages by cationic polysaccharide from Bletilla striata successfully inhibited the expression of TNF-alpha[J]. J Controll Release， 2009， 134(3):214-220.
    • Relative Articles
    • Supplements(0)
    • Cited By
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索
    Get Citation
    PDF
    XML

    Article Metrics

    Article views (1099) PDF downloads(991) Cited by()
    Proportional views
    Related

    Copyright © Journal of Nanjing University of traditional Chinese Medicine

    Sponsored by：Nanjing University of traditional Chinese MedicineAddress：No.138 xianlin Avenue, Qixia District, Nanjing cityChina Pos：210023

    Tel：025-85811935Email：xb@njucm.edu.cn

    Supported by: Beijing Renhe Information Technology Co., Ltd.    

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return