Volume 34 Issue 6
Nov.  2018
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MENGJing, ZHUJing. Research Progress of Traditional Chinese Medicine on Treatment of Peripheral Neuropathy[J]. Journal of Nanjing University of traditional Chinese Medicine, 2018, 34(6): 634-638.
Citation: MENGJing, ZHUJing. Research Progress of Traditional Chinese Medicine on Treatment of Peripheral Neuropathy[J]. Journal of Nanjing University of traditional Chinese Medicine, 2018, 34(6): 634-638.

Research Progress of Traditional Chinese Medicine on Treatment of Peripheral Neuropathy

  • Publish Date: 2018-11-10
  • Chemotherapy induced peripheral neuropathy (CIPN) is chemotherapy drugs induced neurotoxicity occurred in anticancer treatment. Unfortunately, there is no specific clinical drug yet, only mainly symptomatic treatments with analgesics and sedative drugs are applied. CIPN can result in treatment delay,dose modification and termination of chemotherapy. Traditional Chinese medicine theory holds that CIPN is caused by arthromyodynia, previous study showed that Chinese medicine could effectively prevent the complications,but this is limited to clinical reporting, and also lacks support of sufficient evidence and system study. This Review provides a crucial update of the pathogenesis of CIPN and related signaling pathway with Chinese medicine treatment. It will provide a basic reference for the clinical treatment of CIPN.

     

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  • [1]
    IZYCKI D, NIEZGODA AA, KAZMIERCZAK M, et al. Chemotherapy-induced peripheral neuropathy diagnosis, evolution and treatment[J]. Ginekologia Polska, 2016, 87(7): 516-521.
    [2]
    OCEAN AJ, VAHDAT LT. Chemotherapy-induced peripheral neuropathy: pathogenesis and emerging therapies[J]. Support Care Cancer, 2004, 12(9): 619-625.
    [3]
    SAAD M, TAFANI C, PSIMARAS D, et al. Chemotherapy-induced peripheral neuropathy in the adult[J]. Curr Opin Oncol, 2014, 26(6):634-641.
    [4]
    RAO RD, MICHALAK JC, SLOAN JA, et al. Efficacy of gabapentin in the management of chemotherapy-induced peripheral neuropathy: a phase 3 randomized double-blind, placebo-controlled, crossover trial (N00C3) [J]. Cancer, 2007, 110(9): 2110-2118.
    [5]
    CAROZZI VA, CANTA A, CHIORAZZI A. Chemotherapy-induced peripheral neuropathy: What do we know about mechanisms? [J]. Neurosci Lett, 2015, 596: 90-107.
    [6]
    JIANG SP, ZHANG ZD, KANG LM, et al. Celecoxib reverts oxaliplatin-induced neuropathic pain through inhibiting PI3K/Akt2 pathway in the mouse dorsal root ganglion[J]. Exp Neurol, 2016, 275(1): 11-16.
    [7]
    LI D, KIM W, SHIN D, et al. Preventive effects of bee venom derived phospholipase A2 on oxaliplatin-induced neuropathic pain in mice[J]. Toxins, 2016, 8(1): 27.
    [8]
    HADZIC T, AYKIN-BURN N, ZHU Y, et al. Paclitaxel combined with inhibitors of glucose and hydroperoxide metabolism enhances breast cancer cell killing via H2O2 -mediated oxidative stress [J]. Free Radic Biol Med, 2010, 48(8): 1024-1033.
    [9]
    ZHENG H, XIAO WH, BENNETT GJ, et al. Functional deficits in peripheral nerve mitochondria in rats with paclitaxel- and oxaliplatin-evoked painful peripheral neuropathy[J]. Exp Neurol, 2011, 232(2): 154-161.
    [10]
    AZEVEDO MI, PEREIRA AF, NOGUEIRA RB, et al. The antioxidant effects of the flavonoids rutin and quercetin inhibit oxaliplatin-induced chronic painful peripheral neuropathy[J]. Mol Pain, 2013, 9(1): 53.
    [11]
    DI CESARE ML, ZANARDELLI M, FAILLI P, et al. Oxaliplatin-induced neuropathy: oxidative stress as pathological mechanism[J]. J Pain, 2012, 13(3):276-284.
    [12]
    TA LE, BIEBER AJ, CARLTON SM, et al. Transient Receptor Potential Vanilloid 1 is essential for cisplatin-induced heat hyperalgesia in mice[J]. Mol Pain, 2010,6,15.
    [13]
    TAGUCHI K. Role of transient receptor potential channels in paclitaxel- and oxaliplatin-induced peripheral neuropathy[J]. Yakugaku Zasshi, 2016. 136(2): 287-296.
    [14]
    YAMAMOTO K, CHIBA N, CHIBA T, et al. Transient receptor potential ankyrin 1 that is induced in dorsal root ganglion neurons contributes to acute cold hypersensitivity after oxaliplatin administration[J]. Mol Pain, 2015, 11:69.
    [15]
    KAWASHIRI T, EGASHIRA N, KUROBE K, et al. L type Ca2+ channel blockers prevent oxaliplatin -induced cold hyperalgesia and TRPM8 overexpression in rats[J]. Mol Pain, 2012,8:7.
    [16]
    SCUTERI A, GALIMBERTI A, MAGGIONI D, et al. Role of MAPKs in platinum-induced neuronal apoptosis[J]. Neurotoxicology, 2009, 30(2): 312-319.
    [17]
    SCUTERI A, GALIMBERTI A, RAVASI M, et al. NGF protects dorsal root ganglion neurons from oxaliplatin by modulating JNK/Sapk and ERK1/2[J]. Neurosci Lett, 2010, 486(3):141-145.
    [18]
    LI Y, ZHANG H, KOSTURAKIS AK, et al. MAPK signaling downstream to TLR4 contributes to paclitaxel-induced peripheral neuropathy[J]. Brain Behav Immun, 2015, 49:255-266.
    [19]
    LI Y, ZHANG H, ZHANG H, et al. Toll-like receptor 4 signaling contributes to paclitaxel-induced peripheral neuropathy[J]. J Pain, 2014, 15(7): 712-25.
    [20]
    ARETI A, YERRA VG, NAIDU V, et al. Oxidative stress and nerve damage: Role in chemotherapy induced peripheral neuropathy[J]. Redox Biology, 2014, 2:289-295.
    [21]
    张璐.张氏医通[M].北京:中国中医药出版社,1995: 85.
    [22]
    沈金鳌. 杂病源流犀烛(卷十三).刻本[M]. 湖北:崇文书局, 1874:2-10.
    [23]
    黄帝内经素问[M]. 北京:中国医药科技出版社, 2016:155-185.
    [24]
    刘育明.加减补阳还五汤治疗肿瘤化疗后神经损伤的临床观察[J].现代肿瘤医学,2014, 22(8): 1943-1945.
    [25]
    张振,孙亚红,安玉姬,等.补阳还五汤膏剂防治含紫杉醇方案化疗致外周神经毒性临床研究[J].山东中医杂志, 2017, 36(5): 383-384,389.
    [26]
    霍介格,胡莹,杨杰,等.黄芪桂枝五物汤对化疗致大鼠周围神经损伤的作用[J].中医杂志, 2012,53(23):2031-2034.
    [27]
    李道明,王蓉,谢菁,等.黄芪桂枝五物汤治疗奥沙利铂化疗后周围神经毒性24例[J].南京中医药大学学报, 2014,30(2):186-188.
    [28]
    吴冠楠,姚学权,吴晓宇,等. 黄芪桂枝五物汤加减防治术后化疗所致周围神经毒性疗效观察[J]. 四川中医, 2015, 33(12):132-133.
    [29]
    陈宇鹏.加味当归四逆汤预防治疗奥沙利铂所致神经毒性35例临床观察[J].临床医药实践,2009, 2(3):1507-1508.
    [30]
    胡莹.当归四逆汤防治奥沙利铂致慢性外周神经毒性实验研究[D].南京:南京中医药大学,2012.
    [31]
    王静. 参附注射液对奥沙利铂神经毒性的预防作用[J].现代中西医结合杂志, 2012,21(24):2659-2660.
    [32]
    计磊,陈世壮.参麦注射液降低紫杉醇周围神经毒性反应的临床观察[J].实用医药杂志, 2013, 30(3): 232.
    [33]
    朱红丽,穆晓燕,张华平.参麦注射液在预防奥沙利铂所致周围神经毒性中的应用[J].中国实用神经疾病杂志, 2013,16(11):36-38.
    [34]
    魏晓晨,朱立勤,王春革,等. 参麦注射液预防恶性肿瘤化疗所致周围神经毒性效果的系统评价[J].山东医药,2016, 56(28): 45-47.
    [35]
    崔慧娟,李欧静,谭煌英,等. 黄芪注射液防治含奥沙利铂化疗方案所致神经毒性效果的临床观察[J].药物不良反应杂志,2009,11(4):249-252.
    [36]
    骆曼.黄芪注射液防治结直肠癌患者奥沙利铂相关性神经毒性的临床研究[D].武汉:湖北中医药大学,2012.
    [37]
    钟敏钰,罗秀丽. 川芎嗪对紫杉醇致神经病理性疼痛大鼠的疗效及其对坐骨神经中神经生长因子表达的影响[J]. 临床神经病学杂志,2016,29(3):198-202.
    [38]
    高云. 川芎嗪对初级感觉神经元P2X3受体介导的痛觉传递的影响和机制研究[D].南昌:南昌大学,2007.
    [39]
    MENDONCA LM, DA Silva MC, COREIA T, et al. Curcumin reduces cisplatin-induced neurotoxicity in NGF-differentiated PC12 cells[J]. Neuro Toxicology, 2013, 34: 205-211.
    [40]
    DAI CS, CICCOTOSTO GD, CAPPAI R, et al. Curcumin attenuates colistin-induced neurotoxicity in N2a cells via anti-inflammatory activity, suppression of oxidative stress, and apoptosis[J]. Mol Neurobiol, 2018,55(1): 421-434.
    [41]
    BABU A, PRASANTH KG, BALAJI B, et al. Effect of curcumin in mice model of vincristine-induced neuropathy[J]. Pharm Biol, 2015,53(6):838-848.
    [42]
    闫晓方,许伟,高吉照. 苦参碱联合顺铂对SH-SY5Y细胞药物敏感性及TrkB表达的影响[J].临床儿科杂志,2012, 30(5): 456-459.
    [43]
    FAN H, LI L, ZHANG X, et al. Oxymatrine down regulates TLR4, TLR2, MyD88, and NF-κB and protects rat brains against Focal Ischemia[J]. Mediat Inflamm, 2009: 704-706.
    [44]
    赵雪莹,滕林,李冀. 金铃子散镇痛作用的实验研究[J].中医药学报,2012,40(1):61-62.
    [45]
    何钟德. 延胡索甲、乙素对坐骨神经痛大鼠止痛作用及其抗TRPV-1机理的研究[D]. 广州:广州中医药大学, 2012.
    [46]
    HUANG JY, FANG M, LI YJ, et al. Analgesic effect of Corydalis yanhusuo in a rat model of trigeminal neuropathic pain[J]. J South Med Univ,2010, 30(9):2161-2164.
    [47]
    CHOI JG, KANG SY, KIM JM, et al. Antinociceptive effect of Cyperi rhizoma and Corydalis tuber extracts on neuropathic pain in rats[J]. Korean J Physiol Pharmacol, 2012, 16(6):387-392.
    [48]
    ZHOU HH, WU DL, GAO LY, et al. L-Tetrahydropalmatine alleviates mechanical hyperalgesia in models of chronic inflammatory and neuropathic pain in mice[J]. Neuro Rep, 2016, 27(7):476-480.
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