Volume 40 Issue 1
Jan.  2024
Turn off MathJax
Article Contents
Article Navigation >  Journal of Nanjing University of traditional Chinese Medicine  > 2024  >  40(1): 94-108
HU Yang, ZHAO Mian, QIU Yuxuan, YE Debao, LIU Yangqing, ZHANG Chaofeng, WANG Haibo, CHENG Jianming. Research Progress on Dendrobii Officinalis Caulis as Medicinal and Edible Traditional Chinese Medicine[J]. Journal of Nanjing University of traditional Chinese Medicine, 2024, 40(1): 94-108. doi: 10.14148/j.issn.1672-0482.2024.0094
Citation: HU Yang, ZHAO Mian, QIU Yuxuan, YE Debao, LIU Yangqing, ZHANG Chaofeng, WANG Haibo, CHENG Jianming. Research Progress on Dendrobii Officinalis Caulis as Medicinal and Edible Traditional Chinese Medicine[J]. Journal of Nanjing University of traditional Chinese Medicine, 2024, 40(1): 94-108. doi: 10.14148/j.issn.1672-0482.2024.0094
shu

Research Progress on Dendrobii Officinalis Caulis as Medicinal and Edible Traditional Chinese Medicine

doi: 10.14148/j.issn.1672-0482.2024.0094
  • 1.

    School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, China

  • 2.

    State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China

  • 3.

    Kangmei (Bozhou) Huatuo International Chinese Medicine City Commercial Co., Ltd, Bozhou 236800, China

  • 4.

    School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing 211198, China

  • Received Date: 2023-07-30
    Available Online: 2024-01-24
    Abstract
  • Tiepishihu (Dendrobii officinalis Caulis) is a medicinal and food source herbal medicine with the effect of benefiting stomach and promoting fluid, nourishing Yin and clearing heat. It has rich chemical components and pharmacological activities, with anti-inflammatory, anti-bacterial, anti-oxidation, anti-tumor, immunomodulatory, blood press regulation, hypoglycemic effects. It is not only used as medicinal food and health care products, but also widely used in medicine, such as Shihu Yeguang Wan, Compound fresh dendrobium granules and other drugs, with high medicinal and economic value. This paper summarized the resource distribution, chemical composition, pharmacological activities, and medicine and food of Dendrobii officinalis Caulis, and analyzed its application status, laying a theoretical foundation for the sustainable development, medicinal and food homologous development and comprehensive utilization of Dendrobii officinalis Caulis.

     

    • FullText(HTML)
  • loading
    • References(102)
  • [1]
    杨明志, 赵菊润, 何伟. 石斛名医临床与食疗应用[M]. 成都: 四川科学技术出版社, 2018.

    YANG M Z, ZHAO J R, HE W. Clinical and dietotherapy application of Dendrobium nobile[M]. Chengdu: Sichuan Scientific & Technical Publishers, 2018.
    [2]
    国家药典委员会. 中国药典: 一部[M]. 北京: 中国医药科技出版社, 2020.

    China Pharmacopoeia Committee. Pharmacopoeia of the People's Republic of China: Ⅰ[M]. Beijing: China Medical Science and Technology Press, 2020.
    [3]
    杨明志, 单玉莹, 陈晓梅, 等. 中国石斛产业发展现状分析与考量[J]. 中国现代中药, 2022, 24(8): 1395-1402.

    YANG M Z, SHAN Y Y, CHEN X M, et al. Current development situation of Dendrobium industry in China[J]. Mod Chin Med, 2022, 24(8): 1395-1402.
    [4]
    严静, 蔡易熹, 陈燕兰, 等. 铁皮石斛茎、叶、花的活性成分及综合利用研究进展[J]. 食品与发酵工业, 2021, 47(17): 299-306.

    YAN J, CAI Y X, CHEN Y L, et al. Research progress in active components and comprehensive utilization of stems, leaves and flowers of Dendrobium officinale[J]. Food Ferment Ind, 2021, 47(17): 299-306.
    [5]
    刘羽佳, 陈堰珊, 理雅, 等. 铁皮石斛种质资源与遗传改良研究进展[J]. 韶关学院学报, 2022, 43(12): 1-6.

    LIU Y J, CHEN Y S, LI Y, et al. Advances in germplasm resources and genetic improvement of Dendrobium officinale[J]. J Shaoguan Univ, 2022, 43(12): 1-6.
    [6]
    李朝锋, 张向军, 陈晨, 等. 广西铁皮石斛产业发展现状及对策[J]. 现代农业科技, 2019(6): 57-59.

    LI C F, ZHANG X J, CHEN C, et al. Development situation of Dendrobium officinale industry in Guangxi and its countermeasures[J]. Mod Agric Sci Technol, 2019(6): 57-59.
    [7]
    罗在柒, 龙启德, 姜运力, 等. 全国石斛产业现状及贵州发展石斛产业的思考[J]. 贵州林业科技, 2021, 49(1): 42-47.

    LUO Z Q, LONG Q D, JIANG Y L, et al. The Current situation of Dendrobium industry in China and some thoughts on the development in Guizhou[J]. Guizhou For Sci Technol, 2021, 49(1): 42-47.
    [8]
    黄丽. 加快云南石斛产业发展的几点思考[J]. 云南农业科技, 2010(3): 60-62. doi: 10.3969/j.issn.1000-0488.2010.03.027

    HUANG L. Some thoughts on accelerating the development of Dendrobium industry in Yunnan[J]. Yunnan Agric Sci Technol, 2010(3): 60-62. doi: 10.3969/j.issn.1000-0488.2010.03.027
    [9]
    普映娟. 云南铁皮石斛生态环境中的数学方法研究[J]. 数学的实践与认识, 2012, 42(21): 136-140. doi: 10.3969/j.issn.1000-0984.2012.21.018

    PU Y J. The research of mathematical method at Dendrobium officinale ecological environment in Yunnan[J]. Math Pract Theory, 2012, 42(21): 136-140. doi: 10.3969/j.issn.1000-0984.2012.21.018
    [10]
    王全春, 张榆琴, 李明辉, 等. 云南石斛产业发展中存在的问题与对策建议[J]. 安徽农业科学, 2015, 43(5): 70-72. doi: 10.3969/j.issn.0517-6611.2015.05.028

    WANG Q C, ZHANG Y Q, LI M H, et al. Problems and countermeasures of Yunnan Dendrobium industry development[J]. J Anhui Agric Sci, 2015, 43(5): 70-72. doi: 10.3969/j.issn.0517-6611.2015.05.028
    [11]
    赵鹂, 张四海, 骆争荣, 等. 铁皮石斛产业发展现状与对策[J]. 园艺与种苗, 2016, 36(6): 12-13, 70.

    ZHAO L, ZHANG S H, LUO Z R, et al. Current situation and countermeasures of Dendrobium industry[J]. Hortic Seed, 2016, 36(6): 12-13, 70.
    [12]
    陈祖阳. 浙江省乐清市铁皮石斛产业发展研究[J]. 农村经济与科技, 2022, 33(19): 81-83.

    CHEN Z Y. Study on the industrial development of Dendrobium candidum in Yueqing city, Zhejiang Province[J]. Rural Econ Sci Technol, 2022, 33(19): 81-83.
    [13]
    占菁, 周红伟, 程红田. 铁皮石斛林下立体栽培管理技术探究: 以浙江省衢州市为例[J]. 广东蚕业, 2022, 56(7): 57-59.

    ZHAN J, ZHOU H W, CHENG H T. Research on the three-dimensional cultivation management technology of Dendrobium officinale forest-Taking Quzhou city in Zhejiang Province as an example[J]. Guangdong Seric, 2022, 56(7): 57-59.
    [14]
    陶盛昌. 铁皮石斛水溶性多糖分离纯化、结构特征及免疫活性研究[D]. 广州: 广州中医药大学, 2016.

    TAO S C. Study on structural idenfication and immune activity of water-soluble polysaccharides from the stems of Dendrobium Officinale. Kimum et migo[D]. Guangzhou: Guangzhou University of Chinese Medicine, 2016.
    [15]
    张霞, 白月明, 谢雪勤, 等. 铁皮石斛多糖分离纯化及其药理活性研究进展[J]. 食品工业科技, 2022, 43(24): 412-422.

    ZHANG X, BAI Y M, XIE X Q, et al. Research progress on isolation, purification and pharmacological activities of Dendrobium officinale polysaccharide[J]. Sci Technol Food Ind, 2022, 43(24): 412-422.
    [16]
    赵苑伶, 张雪, 陈林珍, 等. 铁皮石斛多糖的分离纯化及抗衰老活性研究[J]. 世界中医药, 2022, 17(17): 2410-2415.

    ZHAO Y L, ZHANG X, CHEN L Z, et al. Separation, purification, and anti-aging activity of caulis dendrobii officinalis polysaccharides[J]. World Chin Med, 2022, 17(17): 2410-2415.
    [17]
    张小辉. 铁皮石斛多糖的纯化工艺及免疫活性研究[D]. 广州: 广东工业大学, 2021.

    ZHANG X H. Study on purification process and evaluation of immune activity of polysaccharides from Dendrobium candidum[D]. Guangzhou: Guangdong University of Technology, 2021.
    [18]
    ZHANG Y, WU Z J, LIU J X, et al. Identification of the core active structure of a Dendrobium officinale polysaccharide and its protective effect against dextran sulfate sodium-induced colitis via alleviating gut microbiota dysbiosis[J]. Food Res Int, 2020, 137: 109641. doi: 10.1016/j.foodres.2020.109641
    [19]
    KUANG M T, LI J Y, YANG X B, et al. Structural characterization and hypoglycemic effect via stimulating glucagon-like peptide-1 secretion of two polysaccharides from Dendrobium officinale[J]. Carbohydr Polym, 2020, 241: 116326. doi: 10.1016/j.carbpol.2020.116326
    [20]
    LI M X, YUE H, WANG Y Q, et al. Intestinal microbes derived butyrate is related to the immunomodulatory activities of Dendrobium officinale polysaccharide[J]. Int J Biol Macromol, 2020, 149: 717-723. doi: 10.1016/j.ijbiomac.2020.01.305
    [21]
    LIU Y G, YANG L L, ZHANG Y, et al. Dendrobium officinale polysaccharide ameliorates diabetic hepatic glucose metabolism via glucagon-mediated signaling pathways and modifying liver-glycogen structure[J]. J Ethnopharmacol, 2020, 248: 112308. doi: 10.1016/j.jep.2019.112308
    [22]
    XING L, MIAO Y L, LI N, et al. Molecular structure features and lactic acid fermentation behaviors of water- and alkali-soluble polysaccharides from Dendrobium officinale[J]. J Food Sci Technol, 2021, 58(2): 532-540. doi: 10.1007/s13197-020-04564-6
    [23]
    ZHANG K, ZHOU X T, WANG J Q, et al. Dendrobium officinale polysaccharide triggers mitochondrial disorder to induce colon cancer cell death via ROS-AMPK-autophagy pathway[J]. Carbohydr Polym, 2021, 264: 118018. doi: 10.1016/j.carbpol.2021.118018
    [24]
    WANG L X, LI C Y, HU C, et al. Purification and structural characterization of Dendrobium officinale polysaccharides and its activities[J]. Chem Biodivers, 2021, 18(5): e2001023. doi: 10.1002/cbdv.202001023
    [25]
    孟继坤, 张楠, 吴浩, 等. 超高压提取铁皮石斛多糖工艺优化及其抗氧化活性分析[J]. 食品与机械, 2023, 39(1): 157-163.

    MENG J K, ZHANG N, WU H, et al. Optimization of ultra-high pressure extraction technology of polysaccharide from Dendrobium officinale and its antioxidant activities[J]. Food Mach, 2023, 39(1): 157-163.
    [26]
    XU L, ZENG X X, LIU Y N, et al. Inhibitory effect of Dendrobium officinale polysaccharide on oxidative damage of glial cells in aging mice by regulating gut microbiota[J]. Int J Biol Macromol, 2023, 247: 125787. doi: 10.1016/j.ijbiomac.2023.125787
    [27]
    WANG K P, SONG M Z, MU X, et al. Comparison and the lipid-lowering ability evaluation method discussion of Dendrobium officinale polysaccharides from different origins based on principal component analysis[J]. Int J Biol Macromol, 2023, 242(Pt 1): 124707.
    [28]
    TAO S C, SONG Y C, DING S B, et al. Dendrobium officinale polysaccharide-based carrier to enhance photodynamic immunotherapy[J]. Carbohydr Polym, 2023, 317: 121089. doi: 10.1016/j.carbpol.2023.121089
    [29]
    LIU H D, XING Y, WANG Y B, et al. Dendrobium officinale polysaccharide prevents diabetes via the regulation of gut microbiota in prediabetic mice[J]. Foods, 2023, 12(12): 2310. doi: 10.3390/foods12122310
    [30]
    XU L, ZENG X X, LIU Y N, et al. Effect of Dendrobium officinale polysaccharides on central nervous system disease: Based on gut microbiota[J]. Int J Biol Macromol, 2023, 240: 124440.
    [31]
    CHEN L, HE X, WANG H X, et al. Dendrobium officinale polysaccharide prevents neuronal apoptosis via TET2-dependent DNA demethylation in high-fat diet-induced diabetic mice[J]. Int J Biol Macromol, 2023, 233: 123288.
    [32]
    CAI M, ZHU H, XU L, et al. Structure, anti-fatigue activity and regulation on gut microflora in vivo of ethanol-fractional polysaccharides from Dendrobium officinale[J]. Int J Biol Macromol, 2023, 234: 123572.
    [33]
    JING Y S, HU J Y, ZHANG Y M, et al. Structural characterization and preventive effect on alcoholic gastric mucosa and liver injury of a novel polysaccharide from Dendrobium officinale[J]. Nat Prod Res, 2022: 1-8.
    [34]
    李镜锐, 陶文扬, 杨颖, 等. 三种浙产铁皮石斛多糖的结构及免疫功效探究[J]. 浙江农业学报, 2023, 35(8): 1888-1895.

    LI J R, TAO W Y, YANG Y, et al. Comparative studies of polysaccharides of three Dendrobium species from Zhejiang Province and exploration of their physiological functions[J]. Acta Agric Zhejiangensis, 2023, 35(8): 1888-1895.
    [35]
    赵小丹, 刘玉, 陶新玉, 等. 不同相对分子质量的铁皮石斛多糖对细胞免疫活性的影响[J]. 中国药学杂志, 2023, 58(11): 997-1004.

    ZHAO X D, LIU Y, TAO X Y, et al. Cellular immune activity ofDendrobium officinale polysaccharide with different molecular weight[J]. Chin Pharm J, 2023, 58(11): 997-1004.
    [36]
    周金平, 王自凡, 卢永仲, 等. 铁皮石斛多糖分级制备及理化活性研究[J]. 日用化学品科学, 2022, 45(8): 17-21.

    ZHOU J P, WANG Z F, LU Y Z, et al. Fractionated preparation and physicochemical properties of dendrobium officinale polysaccharide[J]. Deterg Cosmet, 2022, 45(8): 17-21.
    [37]
    WANG H Y, GE J C, ZHANG F Y, et al. Dendrobium officinale polysaccharide promotes M1 polarization of TAMs to inhibit tumor growth by targeting TLR2[J]. Carbohydr Polym, 2022, 292: 119683.
    [38]
    雷思敏, 肖榕, 章莹, 等. 铁皮石斛中性多糖分离纯化及其体内免疫调节作用研究[J]. 中药新药与临床药理, 2018, 29(6): 748-753.

    LEI S M, XIAO R, ZHANG Y, et al. Seperation and purification of neutral polysaccharides from Dendrobium officinale and study of its immunoregulatory effects[J]. Tradit Chin Drug Res Clin Pharmacol, 2018, 29(6): 748-753.
    [39]
    QU J, TAN S Y, XIE X Y, et al. Dendrobium officinale polysaccharide attenuates insulin resistance and abnormal lipid metabolism in obese mice[J]. Front Pharmacol, 2021, 12: 659626.
    [40]
    YANG J R, CHEN H H, NIE Q X, et al. Dendrobium officinale polysaccharide ameliorates the liver metabolism disorders of type Ⅱ diabetic rats[J]. Int J Biol Macromol, 2020, 164: 1939-1948.
    [41]
    LI B, WANG H Y, HUANG J H, et al. Polysaccharide, the active component of Dendrobium officinale, ameliorates metabolic hypertension in rats via regulating intestinal flora-SCFAs-vascular axis[J]. Front Pharmacol, 2022, 13: 935714.
    [42]
    梅威威. 铁皮石斛多糖的制备及其对急性酒精性肝损伤的防护作用研究[D]. 杭州: 浙江中医药大学, 2015.

    MEI W W. Preparation of Dendrobium candidum polysaccharide and its protective effect on acute alcoholic liver injury[D]. Hangzhou: Zhejiang Chinese Medical University, 2015.
    [43]
    DUAN H T, ER-BU A G, DONGZHI Z M, et al. Alkaloids from Dendrobium and their biosynthetic pathway, biological activity and total synthesis[J]. Phytomedicine, 2022, 102: 154132.
    [44]
    李海涛, 李涛, 李银科. 云南铁皮石斛组培苗石斛碱的提取[J]. 玉溪师范学院学报, 2012, 28(8): 26-27.

    LI H T, LI T, LI Y K. Extraction of Dendrobium base from Yunnan Dendrobium tissue culture[J]. J Yuxi Norm Univ, 2012, 28(8): 26-27.
    [45]
    奚航献, 刘晨, 刘京晶, 等. 铁皮石斛化学成分、药理作用及其质量标志物(Q-marker)的预测分析[J]. 中草药, 2020, 51(11): 3097-3109.

    XI H X, LIU C, LIU J J, et al. Chemical components and pharmacological action for Dendrobium officinale and its prediction analysis on Q-marker[J]. Chin Tradit Herb Drug, 2020, 51(11): 3097-3109.
    [46]
    焦春燕. 基于代谢组和转录组分析铁皮石斛生物碱类型及合成途径[D]. 合肥: 安徽农业大学, 2020.

    JIAO C Y. Metabolome and transcriptome analyses reveal the types of alkaloids and their biosynthetic pathways in Dendrobium officinale[D]. Hefei: Anhui Agricultural University, 2020.
    [47]
    诸燕, 张爱莲, 何伯伟, 等. 铁皮石斛总生物碱含量变异规律[J]. 中国中药杂志, 2010, 35(18): 2388-2391.

    ZHU Y, ZHANG A L, HE B W, et al. Quantitive variation of total alkaloids contents in Dendrobium officinale[J]. China J Chin Mater Med, 2010, 35(18): 2388-2391.
    [48]
    汪群红, 何贤君, 鲍珍贝, 等. 不同来源铁皮石斛中多糖、氨基酸和生物碱含量比较[J]. 中药材, 2014, 37(5): 773-775.

    WANG Q H, HE X J, BAO Z B, et al. Comparison of polysaccharide, amino acids and alkaloids in Dendrobium candidum from different sources[J]. J Chin Med Mater, 2014, 37(5): 773-775.
    [49]
    尚喜雨. 不同来源铁皮石斛不同部位生物碱的分布规律研究[J]. 安徽农业科学, 2010, 38(23): 12441-12442.

    SHANG X Y. Research on the distribution of the alkaloids in the different parts of the Dendrobium candidum with various origins[J]. J Anhui Agric Sci, 2010, 38(23): 12441-12442.
    [50]
    罗向红, 李丽娟, 赵婷, 等. 石斛碱对心肌缺血再灌注损伤大鼠的凋亡抑制作用[J]. 中成药, 2023, 45(6): 1839-1844.

    LUO X H, LI L J, ZHAO T, et al. Inhibitory effects of dendrobine on apoptosis in rats with myocardial ischemia-reperfusion injury[J]. Chin Tradit Pat Med, 2023, 45(6): 1839-1844.
    [51]
    陈存武, 陈乃东, 孟云飞, 等. 沉淀敲出法快速发现霍山产铁皮石斛生物碱及其组分抗氧化活性在线测定[J]. 天然产物研究与开发, 2014, 26(7): 1000-1003, 1013.

    CHEN C W, CHEN N D, MENG Y F, et al. Quick recognition of unknown alkaloids from Dendrobium officinale kimura et migo by an alkaloid-knocking-out method and the on-line HPLC-UV-CL analysis of their antioxidant activity[J]. Nat Prod Res Dev, 2014, 26(7): 1000-1003, 1013.
    [52]
    陈玉凤, 孔亚坤, 李江雁, 等. 石斛碱通过miR-499-5p调控糖尿病肾病系膜细胞增殖、上皮间质转化和纤维化[J]. 中国临床药理学杂志, 2023, 39(2): 211-215.

    CHEN Y F, KONG Y K, LI J Y, et al. Dendrobiine regulates mesangial cell proliferation, epithelial mesangial transformation and fibrosis in diabetic nephropathy through miR-499-5p[J]. Chin J Clin Pharmacol, 2023, 39(2): 211-215.
    [53]
    FENG Y, JIA B, FENG Q, et al. Dendrobine attenuates gestational diabetes mellitus in mice by inhibiting Th17 cells[J]. Basic Clin Pharmacol Toxicol, 2021, 128(3): 379-385.
    [54]
    LI Q M, LI X, SU S Q, et al. Dendrobine inhibits dopaminergic neuron apoptosis via MANF-mediated ER stress suppression in MPTP/MPP+-induced Parkinson's disease models[J]. Phytomedicine, 2022, 102: 154193.
    [55]
    孙恒, 胡强, 金航, 等. 铁皮石斛化学成分及药理活性研究进展[J]. 中国实验方剂学杂志, 2017, 23(11): 225-234.

    SUN H, HU Q, JIN H, et al. Research advances in chemical constituents and pharmacological activities of dendrobii officinalis caulis[J]. Chin J Exp Tradit Med Formulae, 2017, 23(11): 225-234.
    [56]
    马国祥, 徐国钧, 徐珞珊, 等. 反相高效液相色谱法测定18种石斛类生药中chrysotoxene, erianin及chrysotoxine的含量[J]. 中国药科大学学报, 1994, 25(2): 103-105.

    MA G X, XU G J, XU L S, et al. Determination of chrysotoxene, erianin and chrysotoxine in 18 species of "shihu"with HPLC[J]. J China Pharm Univ, 1994, 25(2): 103-105.
    [57]
    YAMAKI M, HONDA C. The stilbenoids from Dendrobium plicatile[J]. Phytochemistry, 1996, 43(1): 207-208.
    [58]
    吕英俊, 陈群. 铁皮石斛化学成分研究及其对HepG2细胞胆固醇代谢影响[J]. 中华中医药学刊, 2016, 34(1): 225-228.

    LYU Y J, CHEN Q. Chemical constituents of Dendrobium candidum and their effects on metabolism of cholesterol in HepG2 cell line[J]. Chin Arch Tradit Chin Med, 2016, 34(1): 225-228.
    [59]
    任刚, 陈优婷, 叶金宝, 等. 铁皮石斛叶的化学成分研究[J]. 中草药, 2020, 51(14): 3637-3644.

    REN G, CHEN Y T, YE J B, et al. Phytochemical investigation of leaves of Dendrobium officinale[J]. Chin Tradit Herb Drugs, 2020, 51(14): 3637-3644.
    [60]
    孟威同, 孟晓, 牛丽婷, 等. 铁皮石斛茎中1个新的联苄衍生物[J]. 中国中药杂志, 2023, 48(3): 700-706.

    MENG W T, MENG X, NIU L T, et al. A new bibenzyl derivative from stems of Dendrobium officinale[J]. China J Chin Mater Med, 2023, 48(3): 700-706.
    [61]
    周宇娟, 王俊豪, 徐红, 等. 铁皮石斛联苄类化学成分的研究[J]. 中国中药杂志, 2021, 46(15): 3853-3858.

    ZHOU Y J, WANG J H, XU H, et al. Bibenzyls from Dendrobium officinale[J]. China J Chin Mater Med, 2021, 46(15): 3853-3858.
    [62]
    刘杰. 两种黔产石斛的抗肿瘤物质分析与评价研究[D]. 贵阳: 贵州医科大学, 2022.

    LIU J. Analysis and evaluation of antitumor substances of two species of Dendrobium from Gui Zhou[D]. Guiyang: Guizhou Medical University, 2022.
    [63]
    ZHAO G Y, DENG B W, ZHANG C Y, et al. New phenanthrene and 9, 10-dihydrophenanthrene derivatives from the stems of Dendrobium officinale with their cytotoxic activities[J]. J Nat Med, 2018, 72(1): 246-251.
    [64]
    CHEN D K, SHAO H Y, YANG L, et al. The bibenzyl derivatives of Dendrobium officinale prevent UV-B irradiation induced photoaging via SIRT3[J]. Nat Prod Bioprospect, 2022, 12(1): 1.
    [65]
    吕朝耕, 杨健, 康传志, 等. 铁皮石斛中10种黄酮类成分UPLC-MS/MS测定与多糖组成含量分析[J]. 中国实验方剂学杂志, 2017, 23(17): 47-52.

    LYU C G, YANG J, KANG C Z, et al. Determination of 10 flavonoids by UPLC-MS/MS and analysis of polysaccharide contents and compositions in dendrobii officinalis caulis from different habitats[J]. Chin J Exp Tradit Med Formulae, 2017, 23(17): 47-52.
    [66]
    李芳, 魏云, 陈艳杰. 铁皮石斛茎、叶、花中黄酮含量及其体外抗氧化活性研究[J]. 中医学报, 2019, 34(5): 1020-1023.

    LI F, WEI Y, CHEN Y J. Study on the content of flavonoids in stems, leaves and flowers of Dendrobium officinale kimura & migo and its antioxidant activity in vitro[J]. Acta Chin Med, 2019, 34(5): 1020-1023.
    [67]
    吴建国, 林柳悦, 吴岩斌, 等. 5种不同种质来源铁皮石斛茎含水量、总黄酮及多糖含量分析[J]. 福建中医药, 2019, 50(2): 43-45.

    WU J G, LIN L Y, WU Y B, et al. Analysis of water content, total flavonoids and polysaccharides in stems of Dendrobium candidum from five different germplasm sources[J]. Fujian J Tradit Chin Med, 2019, 50(2): 43-45.
    [68]
    张小凤, 周春花, 张龙开, 等. 丹霞种、云南广南种铁皮石斛中主要黄酮苷的分离鉴定[J]. 中国实验方剂学杂志, 2019, 25(1): 29-34.

    ZHANG X F, ZHOU C H, ZHANG L K, et al. Isolation and identification of main flavonoid glycosides of Dendrobium officinale from Danxia species and Yunnan Guangnan species[J]. Chin J Exp Tradit Med Formulae, 2019, 25(1): 29-34.
    [69]
    梁芷韵, 谢镇山, 黄月纯, 等. 铁皮石斛黄酮苷类成分HPLC特征图谱优化及不同种源特征性分析[J]. 中国实验方剂学杂志, 2019, 25(1): 22-28.

    LIANG Z Y, XIE Z S, HUANG Y C, et al. HPLC characteristic spectrum optimization of flavonoid glycosides on Dendrobium officinale and characteristics analysis of different provenances[J]. Chin J Exp Tradit Med Formulae, 2019, 25(1): 22-28.
    [70]
    冯海林, 彭崇胜, 李晓波. 铁皮石斛叶中黄酮碳苷类成分分离、鉴定及抑制α-葡萄糖苷酶活性研究[J]. 中国药房, 2022, 33(18): 2187-2191.

    FENG H L, PENG C S, LI X B. Study on the separation and identification of flavone C-glycosides from the leaves of Dendrobium officinale and their inhibitory activities to α-gulcosidase[J]. China Pharm, 2022, 33(18): 2187-2191.
    [71]
    缪园欣, 廖明星, 孙爱红, 等. 超声-乙醇法提取铁皮石斛花总黄酮及其体外抗氧化性的研究[J]. 中国酿造, 2019, 38(4): 155-159.

    MIAO Y X, LIAO M X, SUN A H, et al. Extraction of total flavonoids from Dendrobium officinale flowers by ultrasonic-ethanol synergistic and its antioxidant activity[J]. China Brew, 2019, 38(4): 155-159.
    [72]
    王思涵, 陈俊吉, 莫伟彬. 铁皮石斛黄酮干预力竭运动模型大鼠肝脏氧化应激及自噬水平的变化[J]. 中国组织工程研究, 2022, 26(20): 3212-3219.

    WANG S H, CHEN J J, MO W B. Effects of Dendrobium officinale flavonoid on oxidative stress and autophagy in the liver of an exhaustive exercise rat model[J]. Chin J Tissue Eng Res, 2022, 26(20): 3212-3219.
    [73]
    姜一鸣. 铁皮石斛黄酮对小鼠力竭运动后免疫功能影响的实验研究[D]. 济南: 山东师范大学, 2019.

    JIANG Y M. Experimental study on the effect of flavonoids from Dendrobium candidum on immune function of mice after exhaustive exercise[D]. Jinan: Shandong Normal University, 2019.
    [74]
    闫建华, 许晓玲, 李荷莲, 等. 铁皮石斛总黄酮对D-半乳糖所致小鼠衰老模型的影响[J]. 中医学报, 2021, 36(2): 366-370.

    YAN J H, XU X L, LI H L, et al. Effect of Dendrobium officinale flavonoids on senescent model mice induced by D-galactose[J]. Acta Chin Med, 2021, 36(2): 366-370.
    [75]
    曲继旭, 贺雨馨, 陈龙, 等. 3种石斛氨基酸组成及营养评价[J]. 辽宁中医药大学学报, 2018, 20(2): 60-62.

    QU J X, HE Y X, CHEN L, et al. Determination of amino acids in three Dendrobium species and nutritional evaluation[J]. J Liaoning Univ Tradit Chin Med, 2018, 20(2): 60-62.
    [76]
    罗绪强, 周金星, 张桂玲, 等. 黔产铁皮石斛不同部位多糖、氨基酸及必需元素含量[J]. 江苏农业科学, 2017, 45(10): 150-153.

    LUO X Q, ZHOU J X, ZHANG G L, et al. Contents of polysaccharides, amino acids and essential elements in different parts of Dendrobium candidum in Guizhou Province[J]. Jiangsu Agric Sci, 2017, 45(10): 150-153.
    [77]
    鲁芹飞, 毕何锋, 林培, 等. 柱前衍生化RP-HPLC测定铁皮石斛鲜品中的氨基酸的含量[J]. 医学研究杂志, 2014, 43(2): 54-57.

    LU Q F, BI H F, LIN P, et al. Determination of amino acids in Dendrobium officinale fresh product with pre-column derivatization RP-HPLC[J]. J Med Res, 2014, 43(2): 54-57.
    [78]
    张爱莲, 魏涛, 斯金平, 等. 铁皮石斛中基本氨基酸含量变异规律[J]. 中国中药杂志, 2011, 36(19): 2632-2635.

    ZHANG A L, WEI T, SI J P, et al. Study on basic amino acid contents in Dendrobium officinale[J]. China J Chin Mater Med, 2011, 36(19): 2632-2635.
    [79]
    许春萱, 钟黎, 杜献洲, 等. 人工栽培铁皮石斛中微量元素的测定[J]. 信阳师范学院学报(自然科学版), 2002, 15(4): 411-412.

    XU C X, ZHONG L, DU X Z, et al. Determination of trace elements in D. Candidum[J]. J Xinyang Teach Coll Nat Sci Ed, 2002, 15(4): 411-412.
    [80]
    马小双, 李程程, 丁长春. 广南铁皮石斛重金属及微量元素的测定[J]. 昭通学院学报, 2015, 37(5): 40-42.

    MA X S, LI C C, DING C C. Determination of trace elements and heavy metals of Dendrobium in Guangnan[J]. J Zhaotong Univ, 2015, 37(5): 40-42.
    [81]
    黎万奎, 胡之璧, 周吉燕, 等. 人工栽培铁皮石斛与其他来源铁皮石斛中氨基酸与多糖及微量元素的比较分析[J]. 上海中医药大学学报, 2008, 22(4): 80-83.

    LI W K, HU Z B, ZHOU J Y, et al. Comparative analysis of amino acids, polysaccharides and trace elements in Dendrobium officinale from different sources[J]. Acta Univ Tradit Med Sin Pharmacol Shanghai, 2008, 22(4): 80-83.
    [82]
    纪照红, 芮鸿飞, 黎天天, 等. 新疆不同种植年限铁皮石斛营养成分分析与评价[J]. 食品研究与开发, 2018, 39(11): 152-156.

    JI Z H, RUI H F, LI T T, et al. Analysis and quality evaluation of nutritional components of deudrobium officiuale from Xinjiang[J]. Food Res Dev, 2018, 39(11): 152-156.
    [83]
    付涛, 王志龙. GC-MS法分析不同部位仿野生与组培快繁铁皮石斛中的挥发性成分[J]. 中成药, 2015, 37(12): 2702-2709.

    FU T, WANG Z L. Analysis of volatile constituents in different parts of imitative wild and tissue culture and rapid propagation of Dendrobium officinale by GC-MS[J]. Chin Tradit Pat Med, 2015, 37(12): 2702-2709.
    [84]
    吕素华, 徐萌, 张新凤, 等. 11个铁皮石斛杂交家系鲜花的挥发性成分分析[J]. 中国实验方剂学杂志, 2016, 22(6): 52-57.

    LYU S H, XU M, ZHANG X F, et al. Studies on volatile constituents of 11 families of Dendrobium officinale flowers[J]. Chin J Exp Tradit Med Formulae, 2016, 22(6): 52-57.
    [85]
    杨洋, 罗在柒, 黄安香, 等. 气相色谱检测不同种植方式铁皮石斛中石斛碱含量及挥发性成分分析[J]. 分子植物育种, 2016, 14(7): 1835-1840.

    YANG Y, LUO Z Q, HUANG A X, et al. Gas chromatography test different ways of planting tin pattern Dendrobium candidum welcome alkali content and the analysis of volatile components[J]. Mol Plant Breed, 2016, 14(7): 1835-1840.
    [86]
    颜沛沛, 周建金, 叶炜, 等. 铁皮石斛和重唇石斛及其杂交子代花的挥发性成分分析[J]. 热带亚热带植物学报, 2022, 30(4): 558-566.

    YAN P P, ZHOU J J, YE W, et al. Volatile components in flowers of Dendrobium officinale, D. hercoglossum and their hybrids[J]. J Trop Subtrop Bot, 2022, 30(4): 558-566.
    [87]
    张明, 曹佩雪, 周美, 等. SPME-GC-MS法比较野生和栽培铁皮石斛的挥发性成分[J]. 信阳师范学院学报(自然科学版), 2015, 28(2): 239-243.

    ZHANG M, CAO P X, ZHOU M, et al. Comparison of aroma components from wild and cultivated Dendrobium officinale by GC-MS with solid-phase microextraction[J]. J Xinyang Norm Univ Nat Sci Ed, 2015, 28(2): 239-243.
    [88]
    杨柳, 刘守金, 胡江苗, 等. GC-MS法检测铁皮石斛茎中挥发性成分[J]. 中国现代中药, 2013, 15(5): 362-364.

    YANG L, LIU S J, HU J M, et al. Determination of volatile components from stem of Dendrobium officinaleby GC-MS[J]. Mod Chin Med, 2013, 15(5): 362-364.
    [89]
    黄彪, 何伟, 吴建鸿, 等. UPLC-MS/MS同时测定铁皮石斛茎、叶、花中酚类组分的含量[J]. 食品科学, 2021, 42(10): 262-268.

    HUANG B, HE W, WU J H, et al. Simultaneous determination of phenolic components in Dendrobium officinale stems, leaves and flowers by ultra-high performance liquid chromatography-tandem mass spectrometry[J]. Food Sci, 2021, 42(10): 262-268.
    [90]
    唐文文, 沈易华. 不同生长年限铁皮石斛叶主要功效成分及抗氧化活性分析[J]. 江西化工, 2021, 37(4): 60-62.

    TANG W W, SHEN Y H. Analysis of main functional components and antioxidant activity of Dendrobium candidum leavesin different growth years[J]. Jiangxi Chem Ind, 2021, 37(4): 60-62.
    [91]
    魏三同. 铁皮石斛多酚对小鼠力竭运动氧化损伤的防护作用[D]. 济南: 山东师范大学, 2019.

    WEI S T. Protective effect of Dendrobium officinale polyphenols on oxidative damage caused by exhaustive exercise in mice[D]. Jinan: Shandong Normal University, 2019.
    [92]
    王健, 甄彩云, 魏练平, 等. 铁皮石斛茎多糖、木质素积累规律及木质素单体类型鉴定[J]. 植物科学学报, 2021, 39(3): 306-315.

    WANG J, ZHEN C Y, WEI L P, et al. Accumulation regularity of polysaccharides and lignin and identification of lignin monomer types in stems of Dendrobium officinale Kimura et Migo[J]. Plant Sci J, 2021, 39(3): 306-315.
    [93]
    聂少平, 蔡海兰. 铁皮石斛活性成分及其功能研究进展[J]. 食品科学, 2012, 33(23): 356-361.

    NIE S P, CAI H L. Research progress in bioactive components and functions of Dendrobium officinale[J]. Food Sci, 2012, 33(23): 356-361.
    [94]
    刘松华, 马瑜瑾, 何凌云. 铁皮枫斗颗粒联合莫沙比利治疗慢性萎缩性胃炎的临床研究[J]. 现代药物与临床, 2021, 36(10): 2068-2072.

    LIU S H, MA Y J, HE L Y. Clinical study on Tiepi Fengdou Granules combined with mosapride in treatment of chronic atrophic gastritis[J]. Drugs Clin, 2021, 36(10): 2068-2072.
    [95]
    王璟, 董志春, 楼丽颖, 等. 铁皮石斛粉对2型糖尿病患者胰岛功能改善的临床研究[J]. 新中医, 2021, 53(12): 90-93.

    WANG J, DONG Z C, LOU L Y, et al. Clinical study on Dendrobium candidum powder in improving islet function of patients with type 2 diabetes mellites[J]. J N Chin Med, 2021, 53(12): 90-93.
    [96]
    吴俊, 庄煌辉, 毛志田, 等. 龙虎山铁皮石斛治疗高血压病临床观察[J]. 中医药临床杂志, 2018, 30(2): 297-300.

    WU J, ZHUANG H H, MAO Z T, et al. Clinical observation of dendrobium candidum in mount Longhu in the treatment of hypertension[J]. Clin J Tradit Chin Med, 2018, 30(2): 297-300.
    [97]
    金从国, 段林灿, 沈红梅, 等. 铁皮石斛对肺癌循环肿瘤细胞及细胞免疫功能的影响[J]. 湖北中医药大学学报, 2022, 24(2): 23-26.

    JIN C G, DUAN L C, SHEN H M, et al. Effect of on the circulating tumor cells and immune function of lung cancer patients[J]. J Hubei Univ Chin Med, 2022, 24(2): 23-26.
    [98]
    程志源, 邹国斌, 吴苏柳, 等. 鲜铁皮石斛佐治小儿顽固性发热53例疗效观察[J]. 浙江中医杂志, 2017, 52(8): 592.

    CHENG Z Y, ZOU G B, WU S L, et al. Clinical observation on 53 cases of intractable fever in children treated with fresh Dendrobium candidum[J]. Zhejiang J Tradit Chin Med, 2017, 52(8): 592.
    [99]
    敖德平. 一种舒敏修复素及其应用: CN115581653A[P]. 2023-08-04.

    AO D P. A kind of soothing and repairing factor and its application: CN115581653A[P]. 2023-08-04.
    [100]
    梁嘉亮, 张齐, 余力行. 一种促胶原蛋白合成的铁皮石斛提取物及其制备方法和应用: CN116509783A[P]. 2023-08-01.

    LIANG J L, ZHANG Q, YU L X. Dendrobium officinale extract for promoting collagen synthesis as well as preparation method and application of Dendrobium officinale extract: CN116509783A[P]. 2023-08-01.
    [101]
    林霁, 招敏聪, 李璐, 等. 一种含铁皮石斛提取物的肌底精华液及其制备方法: CN113633599B[P]. 2023-03-24.

    LIN J, ZHAO M C, LI L, et al. Skin base essence containing dendrobium officinale extract and preparation method of skin base essence containing dendrobium officinale extract: CN113633599B[P]. 2023-03-24. .
    [102]
    蒋梦雨, 杨创, 陈宇, 等. 大数据视域下铁皮石斛专利/文献可视化分析[J]. 西南大学学报(自然科学版), 2022, 44(7): 76-86.

    JIANG M Y, YANG C, CHEN Y, et al. Visual analysis of patents and documents on Dendrobium officinale under the perspective of big data[J]. J Southwest Univ Nat Sci Ed, 2022, 44(7): 76-86.
    • Relative Articles
    • Supplements(0)
    • Cited By
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Figures(5)  / Tables(6)

    Get Citation
    PDF
    XML

    Article Metrics

    Article views (639) PDF downloads(80) Cited by()
    Proportional views
    Related

    Copyright © Journal of Nanjing University of traditional Chinese Medicine

    Sponsored by：Nanjing University of traditional Chinese MedicineAddress：No.138 xianlin Avenue, Qixia District, Nanjing cityChina Pos：210023

    Tel：025-85811935Email：xb@njucm.edu.cn

    Supported by: Beijing Renhe Information Technology Co., Ltd.    

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return