Citation: | XU Qi, ZHANG Hong-rong, XU Wei-min, QIAN Jia-jia, HUANG Gui-cheng. Based on HMGB1/NF-κB Signal Pathway to Explore Inhibitory Effect of Wenjing Tongluo Decoction on IL-1β-Induced Inflammation in Primary Chondrocytes in Mice[J]. Journal of Nanjing University of traditional Chinese Medicine, 2023, 39(11): 1095-1101. doi: 10.14148/j.issn.1672-0482.2023.1095 |
[1] |
MOLNAR V, MATISIC V, KODVANJ I, et al. Cytokines and chemokines involved in osteoarthritis pathogenesis[J]. Int J Mol Sci, 2021, 22(17): 9208. doi: 10.3390/ijms22179208
|
[2] |
NEDUNCHEZHIYAN U, VARUGHESE I, SUN AR, et al. Obesity, inflammation, and immune system in osteoarthritis[J]. Front Immunol, 2022, 13: 907750. doi: 10.3389/fimmu.2022.907750
|
[3] |
WARMINK K, VINOD P, KORTHAGEN NM, et al. Macrophage-driven inflammation in metabolic osteoarthritis: Implications for biomarker and therapy development[J]. Int J Mol Sci, 2023, 24(7): 6112. doi: 10.3390/ijms24076112
|
[4] |
PAUDEL YN, ANGELOPOULOU E, PIPERI C, et al. Enlightening the role of high mobility group box 1 (HMGB1) in inflammation: Updates on receptor signalling[J]. Eur J Pharmacol, 2019, 858: 172487. doi: 10.1016/j.ejphar.2019.172487
|
[5] |
ZAKI AM, EL-TANBOULY DM, ABDELSALAM RM, et al. Plumbagin ameliorates hepatic ischemia-reperfusion injury in rats: Role of high mobility group box 1 in inflammation, oxidative stress and apoptosis[J]. Biomed Pharmacother, 2018, 106: 785-793. doi: 10.1016/j.biopha.2018.07.004
|
[6] |
WANG SM, ZHANG Y. HMGB1 in inflammation and cancer[J]. J Hematol Oncol, 2020, 13(1): 116. doi: 10.1186/s13045-020-00950-x
|
[7] |
钱佳佳, 许奇, 许炜民, 等. 温经通络汤对膝骨关节炎模型小鼠膝关节软骨组织HMGB1/NF-κB信号通路的影响[J]. 中医杂志, 2023, 64(9): 939-947. https://www.cnki.com.cn/Article/CJFDTOTAL-ZZYZ202309013.htm
QIAN JJ, XU Q, XU WM, et al. Effect of Wenjing Tongluo decoction on HMGB1/NF-κB signaling pathway in knee articular cartilage tissue of knee osteoarthritis model mice[J]. J Tradit Chin Med, 2023, 64(9): 939-947. https://www.cnki.com.cn/Article/CJFDTOTAL-ZZYZ202309013.htm
|
[8] |
YIN CY, BAI QF, FENG JX. miR-216a-5p protects 16HBE cells from H2O2-induced oxidative stress through targeting HMGB1/NF-kB pathway[J]. Biochem Biophys Res Commun, 2019, 508(2): 416-420. doi: 10.1016/j.bbrc.2018.11.060
|
[9] |
FU YH, LEI JL, ZHUANG Y, et al. Overexpression of HMGB1 A-box reduced IL-1β-induced MMP expression and the production of inflammatory mediators in human chondrocytes[J]. Exp Cell Res, 2016, 349(1): 184-190. doi: 10.1016/j.yexcr.2016.10.014
|
[10] |
陈晨, 马勇, 黄桂成, 等. 黄桂成运用温经通络汤治疗膝骨关节炎经验[J]. 中国民间疗法, 2019, 27(23): 8-10. https://www.cnki.com.cn/Article/CJFDTOTAL-ZMJL201923007.htm
CHEN C, MA Y, HUANG GC, et al. Huang Guicheng's experience in treating knee osteoarthritis with Wenjing Tongluo Decoction[J]. China's Naturopathy, 2019, 27(23): 8-10. https://www.cnki.com.cn/Article/CJFDTOTAL-ZMJL201923007.htm
|
[11] |
钱佳佳. 基于蛋白组学研究温经通络汤调控血管新生治疗膝骨关节炎的作用机制[D]. 南京: 南京中医药大学, 2021.
QIAN JJ. Study on the mechanism of Wenjing Tongluo Decoction regulating angiogenesis in the treatment of knee osteoarthritis based on proteomics[D]. Nanjing: Nanjing University of Chinese Medicine, 2021.
|
[12] |
MOTTA F, BARONE E, SICA A, et al. Inflammaging and osteoarthritis[J]. Clin Rev Allergy Immunol, 2023, 64(2): 222-238.
|
[13] |
LI ZH, HUANG ZY, ZHANG H, et al. P2X7 receptor induces pyroptotic inflammation and cartilage degradation in osteoarthritis via NF-κB/NLRP3 crosstalk[J]. Oxid Med Cell Longev, 2021, 2021: 8868361.
|
[14] |
许奇, 许炜民, 浦元臻, 等. 膝骨关节炎小鼠软骨退变过程及温经通络汤对其治疗作用[J]. 中华中医药杂志, 2022, 37(12): 7070-7075. https://www.cnki.com.cn/Article/CJFDTOTAL-BXYY202212040.htm
XU Q, XU WM, PU YZ, et al. Regularity of cartilage degeneration in mice with knee osteoarthritis and therapeutic effect of Wenjing Tongluo Decoction[J]. China J Tradit Chin Med Pharm, 2022, 37(12): 7070-7075. https://www.cnki.com.cn/Article/CJFDTOTAL-BXYY202212040.htm
|
[15] |
许奇, 钱佳佳, 许炜民, 等. 温经通络汤对膝骨关节炎模型小鼠VEGF/VEGFR2/ERK1/2信号通路的影响[J]. 中国实验方剂学杂志, 2021, 27(13): 28-34. https://www.cnki.com.cn/Article/CJFDTOTAL-ZSFX202113004.htm
XU Q, QIAN JJ, XU WM, et al. Effect of Wenjing Tongluo Decoction on VEGF/VEGFR2/ERK1/2 signaling pathway in mice with knee osteoarthritis[J]. Chin J Exp Tradit Med Formulae, 2021, 27(13): 28-34. https://www.cnki.com.cn/Article/CJFDTOTAL-ZSFX202113004.htm
|
[16] |
许炜民, 钱佳佳, 韩龙, 等. 温经通络汤对小鼠膝骨关节炎软骨形态改变和VEGF、MMP-13、HIF-1α表达情况的影响[J]. 中医药信息, 2020, 37(6): 6-12. https://www.cnki.com.cn/Article/CJFDTOTAL-ZYXN202006002.htm
XU WM, QIAN JJ, HAN L, et al. Effects of Wenjing Tongluo Decoction on changes of cartilage morphology and expressions of VEGF, MMP-13 and HIF-1α in mice with KOA[J]. Inf Tradit Chin Med, 2020, 37(6): 6-12. https://www.cnki.com.cn/Article/CJFDTOTAL-ZYXN202006002.htm
|
[17] |
ZOU ZL, SUN MH, YIN WF, et al. Avicularin suppresses cartilage extracellular matrix degradation and inflammation via TRAF6/MAPK activation[J]. Phytomedicine, 2021, 91: 153657.
|
[18] |
JIA YW, PANG C, ZHAO KX, et al. Correction to: Garcinol suppresses IL-1β-induced chondrocyte inflammation and osteoarthritis via inhibition of the NF-κB signaling pathway[J]. Inflammation, 2020, 43(4): 1586-1587.
|
[19] |
LEPETSOS P, PAPAVASSILIOU KA, PAPAVASSILIOU AG. Redox and NF-κB signaling in osteoarthritis[J]. Free Radic Biol Med, 2019, 132: 90-100.
|
[20] |
YANG G, SUN S, WANG J, et al. S-allylmercaptocysteine targets Nrf2 in osteoarthritis treatment through NOX4/NF-κB pathway[J]. Drug Des Devel Ther, 2020, 14: 4533-4546.
|