Volume 39 Issue 9
Sep.  2023
Turn off MathJax
Article Contents
RUAN Xiao-wen, ZHANG Zi-hao, LI Yan-hui, WU Qiu-mei, ZHU Hao-ran, YIN Chang-ping, WANG Xia-chang, LI Tao, LI Xuan. Study on Quality Control Indicators and Medicinal Value of Vitex Honey[J]. Journal of Nanjing University of traditional Chinese Medicine, 2023, 39(9): 870-878. doi: 10.14148/j.issn.1672-0482.2023.0870
Citation: RUAN Xiao-wen, ZHANG Zi-hao, LI Yan-hui, WU Qiu-mei, ZHU Hao-ran, YIN Chang-ping, WANG Xia-chang, LI Tao, LI Xuan. Study on Quality Control Indicators and Medicinal Value of Vitex Honey[J]. Journal of Nanjing University of traditional Chinese Medicine, 2023, 39(9): 870-878. doi: 10.14148/j.issn.1672-0482.2023.0870

Study on Quality Control Indicators and Medicinal Value of Vitex Honey

doi: 10.14148/j.issn.1672-0482.2023.0870
  • Received Date: 2023-08-11
    Available Online: 2023-10-20
  •   OBJECTIVE  To evaluate the quality control indicators and medicinal value of Vitex Honey.  METHODS  Vitex honey samples from Du'an area of Guangxi in the past four years were collected, and their physicochemical characteristics and effects on the loperamide hydrochloride-induced transmission disorder constipation mouse models were studied.  RESULTS  The pollen grains of the Vitex Honey were mainly from Vitex flower, with a stable water content of less than 20%, conductivity below 0.8 mS·cm-1, pH between 3.67 and 3.93, free acid 27.3 to 32.3 meq·kg-1, lactones 15.6 to 21.5 meq·kg-1, total acid 35.4 to 53.7 meq·kg-1, amylase 17.6 to 21.5 U, hydroxymethylfurfural (5-HMF) 3.3 to 11.6 mg·kg-1, total phenolic content 450 to 650 mg·kg-1, and total flavonoid content 16.3 to 26.6 mg·kg-1, DPPH clearance EC50 ranges from 67.5 to 90.1 mg·mL-1. The results of thin layer identification research showed that Vitex honey exhibited different characteristic spectra compared to more than ten other types of honey, but Vitex honey exhibited relatively consistent spectral characteristics in different years; daily intaking of different concentrations of honey aqueous solution significantly improved and alleviated the constipation symptoms of loperamide hydrochloride-induced transmission disorder constipation in mice.  CONCLUSION  This study provides a beneficial exploration for the formulation of various quality standards for Vitex honey at all levels and the study of its medicinal value, in order to provide a basis for subsequent standard formulation and product development.

     

  • loading
  • [1]
    中华人民共和国卫生部. GB14963-2011, 食品安全国家标准蜂蜜[S]. 北京: 中国标准出版社, 2011.

    Ministry of Health of the People's Republic of China. GB14963-2011, National standard for food safety honey[S]. Beijing: China standards press, 2011.
    [2]
    国家药典委员会. 中华人民共和国药典: 一部[S]. 北京: 中国医药科技出版社, 2020: 374.

    National Pharmacopoeia Commission. Pharmacopoeia of the People's Republic of China: Vol Ⅰ[S]. Beijing: China medical science and technology press, 2020: 374.
    [3]
    ZAMMIT YOUNG GW, BLUNDELL R. A review on the phytochemical composition and health applications of honey[J]. Heliyon, 2023, 9(2): e12507. doi: 10.1016/j.heliyon.2022.e12507
    [4]
    魏丽, 曾志将. 中国部分商品蜂蜜中植物花粉形态、含量及浓度的研究[J]. 中国蜂业, 2009, 60(6): 12-14. https://www.cnki.com.cn/Article/CJFDTOTAL-ZGYF200906006.htm

    WEI L, ZENG ZJ. Study on shape, content and concentration of plant pollen in part commercial honey of China[J]. Apic China, 2009, 60(6): 12-14. https://www.cnki.com.cn/Article/CJFDTOTAL-ZGYF200906006.htm
    [5]
    中华人民共和国卫生部. GB/T 18932.15-2003, 食品安全国家标准蜂蜜[S]. 北京: 中国标准出版社, 2003.

    Ministry of Health of the People's Republic of China. GB/T 18932.15-2003, National standard for food safety honey[S]. Beijing: China standards press, 2003.
    [6]
    Association of Official Analytical Chemists AOAC (1990). AOAC Official Method 962.19 Acidity in Honey[S]. Washington: Association of Official Analytical Chemists.
    [7]
    ISLAM MK, SOSTARIC T, LIM LY, et al. A comprehensive HPTLC-based analysis of the impacts of temperature on the chemical properties and antioxidant activity of honey[J]. Molecules, 2022, 27(23): 8491. doi: 10.3390/molecules27238491
    [8]
    MAKOWICZ E, JASICKA-MISIAK I, TEPER D, et al. HPTLC fingerprinting-rapid method for the differentiation of honeys of different botanical origin based on the composition of the lipophilic fractions[J]. Molecules, 2018, 23(7): 1811. doi: 10.3390/molecules23071811
    [9]
    姚一博, 王迪, 王钱陶, 等. 盐酸洛哌丁胺诱导的小鼠慢传输型便秘模型的实验研究[J]. 中国实验动物学报, 2020, 28(3): 370-375. doi: 10.3969/j.issn.1005-4847.2020.03.012

    YAO YB, WANG D, WANG QT, et al. Experimental study of slow transit constipation induced by loperamide hydrochloride in mice[J]. Acta Lab Animalis Sci Sin, 2020, 28(3): 370-375. doi: 10.3969/j.issn.1005-4847.2020.03.012
    [10]
    张金谈, 王嘉琳. 蜂蜜的花粉分析[J]. 植物学报, 1966, 8(2): 186-192. https://www.cnki.com.cn/Article/CJFDTOTAL-ZWXB196602012.htm

    ZHANG JT, WANG JL. Pollen analysis of honey[J]. J Integr Plant Biol, 1966, 8(2): 186-192. https://www.cnki.com.cn/Article/CJFDTOTAL-ZWXB196602012.htm
    [11]
    赵天祎, 马占峰, 汪驷麒. 蜂蜜电导率的实验研究[J]. 中国蜂业, 2020, 71(7): 40-41. https://www.cnki.com.cn/Article/CJFDTOTAL-ZGYF202007030.htm

    ZHAO TY, MA ZF, WANG SQ. Experimental study on the conductivity of honey[J]. Apic China, 2020, 71(7): 40-41. https://www.cnki.com.cn/Article/CJFDTOTAL-ZGYF202007030.htm
    [12]
    陈雪洋, 田珂雪. 蜂蜜中α-淀粉酶活力测定方法改进[J]. 河南农业, 2020(24): 59-60. https://www.cnki.com.cn/Article/CJFDTOTAL-NYHN202024027.htm

    CHEN XY, TIAN KX. Improvement of determination method of α-amylase activity in honey[J]. Agric Henan, 2020(24): 59-60. https://www.cnki.com.cn/Article/CJFDTOTAL-NYHN202024027.htm
    [13]
    刘佳宁. 浅谈淀粉酶在真假蜂蜜中的区别[J]. 食品安全导刊, 2015(15): 89. https://www.cnki.com.cn/Article/CJFDTOTAL-SPAQ201515049.htm

    LIU JN. On the difference between amylase and true and false honey[J]. China Food Saf Mag, 2015(15): 89. https://www.cnki.com.cn/Article/CJFDTOTAL-SPAQ201515049.htm
    [14]
    吕成军. 分光光度法测定淀粉酶值鉴别蜂蜜质量的一种方法[J]. 农家参谋, 2020(8): 217-218. https://www.cnki.com.cn/Article/CJFDTOTAL-NJCM202008210.htm

    LYU CJ. A method for identifying honey quality by measuring amylase value by spectrophotometry[J]. Farmers Consult, 2020(8): 217-218. https://www.cnki.com.cn/Article/CJFDTOTAL-NJCM202008210.htm
    [15]
    王瑞忠, 鲁静. 薄层色谱和高效液相色谱法鉴别真伪蜂蜜的方法研究[J]. 药物分析杂志, 2014, 34(4): 737-741. https://www.cnki.com.cn/Article/CJFDTOTAL-YWFX201404035.htm

    WANG RZ, LU J. Method study for the determination of adulteration honey by TLC and HPLC[J]. Chin J Pharm Anal, 2014, 34(4): 737-741. https://www.cnki.com.cn/Article/CJFDTOTAL-YWFX201404035.htm
    [16]
    OWENS A, LANE JR, MANLEY-HARRIS M, et al. Kinetics of conversion of dihydroxyacetone to methylglyoxal in New Zealand mānuka honey: Part Ⅴ-The rate determining step[J]. Food Chem, 2019, 276: 636-642.
    [17]
    GRAINGER MNC, MANLEY-HARRIS M, LANE JR, et al. Kinetics of conversion of dihydroxyacetone to methylglyoxal in New Zealand mānuka honey: Part Ⅰ-Honey systems[J]. Food Chem, 2016, 202: 484-491.
    [18]
    GRAINGER MNC, MANLEY-HARRIS M, LANE JR, et al. Kinetics of the conversion of dihydroxyacetone to methylglyoxal in New Zealand mānuka honey: Part Ⅱ-Model systems[J]. Food Chem, 2016, 202: 492-499.
    [19]
    HELLWIG M, RVCKRIEMEN J, SANDNER D, et al. Unique pattern of protein-bound Maillard reaction products in manuka (Leptospermum scoparium) honey[J]. J Agric Food Chem, 2017, 65(17): 3532-3540.
    [20]
    NOLAN VC, HARRISON J, WRIGHT JEE, et al. Clinical significance of manuka and medical-grade honey for antibiotic-resistant infections: A systematic review[J]. Antibiotics, 2020, 9(11): 766.
    [21]
    MCLOONE P, OLUWADUN A, WARNOCK M, et al. Honey: A therapeutic agent for disorders of the skin[J]. Cent Asian J Glob Health, 2016, 5(1): 241.
    [22]
    MUNSTEDT K, MOMM F, HUBNER J. Honey in the management of side effects of radiotherapy- or radio/chemotherapy-induced oral mucositis: A systematic review[J]. Complement Ther Clin Pract, 2019, 34: 145-152.
    [23]
    NAGI R, PATIL DJ, RAKESH N, et al. Natural agents in the management of oral mucositis in cancer patients-systematic review[J]. J Oral Biol Craniofac Res, 2018, 8(3): 245-254.
    [24]
    TSANG KK, KWONG EWY, WOO KY, et al. The anti-inflammatory and antibacterial action of nanocrystalline silver and manuka honey on the molecular alternation of diabetic foot ulcer: A comprehensive literature review[J]. Evid Based Complement Alternat Med, 2015, 2015: 218283.
    [25]
    王龙骧. 黄荆子糖浆的制法与治疗作用[J]. 江西中医药, 1956(10): 46-48. https://www.cnki.com.cn/Article/CJFDTOTAL-JXYY195610008.htm

    WANG LX. Preparation and therapeutic effect of Vitex negundo syrup[J]. Jiangxi Med J, 1956(10): 46-48. https://www.cnki.com.cn/Article/CJFDTOTAL-JXYY195610008.htm
    [26]
    王军华, 胡苹. 黄荆的药理作用[J]. 沈阳医学院学报, 2021, 23(6): 622-624. https://www.cnki.com.cn/Article/CJFDTOTAL-SYYX202106015.htm

    WANG JH, HU P. A review of the pharmacological action of Vitex negundo Linn[J]. J Shenyang Med Coll, 2021, 23(6): 622-624. https://www.cnki.com.cn/Article/CJFDTOTAL-SYYX202106015.htm
    [27]
    ZHENG CJ, LI HQ, REN SC, et al. Phytochemical and pharmacological profile of Vitex negundo[J]. Phytother Res, 2015, 29(5): 633-647.
    [28]
    GILL BS, MEHRA R, NAVGEET, et al. Vitex negundo and its medicinal value[J]. Mol Biol Rep, 2018, 45(6): 2925-2934.
    [29]
    WANG Y, LI D, CHENG N, et al. Antioxidant and hepatoprotective activity of vitex honey against paracetamol induced liver damage in mice[J]. Food Funct, 2015, 6(7): 2339-2349.
    [30]
    柴霞, 许志军, 李芝彪, 等. 荆条蜜对果蝇生长发育和抗氧化能力的影响[J]. 食品工业科技, 2013, 34: 339-343. https://www.cnki.com.cn/Article/CJFDTOTAL-SPKJ201312071.htm

    CHAI X, XU ZJ, LI ZB, et al. Effect of Vitex honey on growth and antioxidantion of Drosophila melanogaster[J]. Sci Tech Food Ind, 2013, 34: 339-343. https://www.cnki.com.cn/Article/CJFDTOTAL-SPKJ201312071.htm
    [31]
    郭顺悦, 乔江涛, 张红城. 荆条蜜中特征性成分鉴定[J]. 中国蜂业, 2020, 71(12): 67-71. https://www.cnki.com.cn/Article/CJFDTOTAL-ZGYF202012034.htm

    GUO SY, QIAO JT, ZHANG HC. Identification of characteristic component in Vitex honey[J]. Apic China, 2020, 71(12): 67-71. https://www.cnki.com.cn/Article/CJFDTOTAL-ZGYF202012034.htm
    [32]
    张永清, 周艺佳, 李梦媛, 等. 应用实时LAMP方法检测荆条蜜源成分[J]. 许昌学院学报, 2021, 40(2): 70-73. https://www.cnki.com.cn/Article/CJFDTOTAL-XCSZ202102017.htm

    ZHANG YQ, ZHOU YJ, LI MY, et al. Application of real-time LAMP method to detect honey-source components of Vitex negundo[J]. J Xuchang Univ, 2021, 40(2): 70-73. https://www.cnki.com.cn/Article/CJFDTOTAL-XCSZ202102017.htm
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Figures(4)  / Tables(2)

    Article Metrics

    Article views (116) PDF downloads(7) Cited by()
    Proportional views
    Related

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return