Citation: | LIU Yuan-yue, HU Dan, DING Cai-xia, LI Chuan-you, XIAO Jing, LI Ting-ting, GUO Xue-yan, SHENG Lei. Effects of Chaihu Plus Longgu Muli Decoction on Microglial Polarization and Synaptic Plasticity in Post-Stroke Depressed Rats[J]. Journal of Nanjing University of traditional Chinese Medicine, 2023, 39(8): 746-752. doi: 10.14148/j.issn.1672-0482.2023.0746 |
[1] |
ZHANG X, TANG Y, XIE Y, et al. Total magnetic resonance imaging burden of cerebral small-vessel disease is associated with post-stroke depression in patients with acute lacunar stroke[J]. Eur J Neurol, 2017, 24(2): 374-380. doi: 10.1111/ene.13213
|
[2] |
于冰清, 邵欣欣, 付晓凡, 等. 抗抑郁中药复方的组方特点及作用机制研究[J]. 中草药, 2021, 52(11): 3344-3352. https://www.cnki.com.cn/Article/CJFDTOTAL-ZCYO202111022.htm
YU BQ, SHAO XX, FU XF, et al. Study on composition characteristics and mechanism of anti-depression traditional Chinese medicine compound based on literature mining and correlation analysis[J]. Chin Tradit Herb Drugs, 2021, 52(11): 3344-3352. https://www.cnki.com.cn/Article/CJFDTOTAL-ZCYO202111022.htm
|
[3] |
李用粹. 证治汇补[M]. 竹剑平, 江凌圳, 胡森等, 整理. 北京: 人民卫生出版社, 2006.
Li YC. Syndrome, Governance and replenishment[M]. ZHU JP, JIANG LZ, HU S, et al. sorted. Beijing: People's medical publishing house, 2006.
|
[4] |
汪琥. 伤寒论辨证广注[M]. 王振亮, 王晓艳, 李亚红等, 校注. 北京: 中国中医药出版社, 2016: 17.
WANG H. General Notes on Syndrome Differentiation of Febrilis[M]. WANG ZL, WANG XY, LI YH, et al. annotated. Beijing: China traditional Chinese medicine press, 2016: 17.
|
[5] |
胡丹, 凌志香, 盛蕾. 加味柴胡疏肝散联合西药对卒中后抑郁患者睡眠影响的临床研究: 附32例临床资料[J]. 江苏中医药, 2018, 50(4): 43-45. https://www.cnki.com.cn/Article/CJFDTOTAL-JSZY201804018.htm
HU D, LING ZX, SHENG L. Clinical study on the effect of modified Chaihu Shugan Powder combined with western medicine on sleep of patients with post-stroke depression—a report of 32 cases[J]. Jiangsu J Tradit Chin Med, 2018, 50(4): 43-45. https://www.cnki.com.cn/Article/CJFDTOTAL-JSZY201804018.htm
|
[6] |
胡丹, 盛蕾. 加味柴胡疏肝颗粒辅助治疗缺血性脑卒中后抑郁的疗效观察[J]. 中草药, 2016, 47(21): 3866-3870. https://www.cnki.com.cn/Article/CJFDTOTAL-ZCYO201621023.htm
HU D, SHENG L. Clinical observation on efficacy of Modified Chaihu Shugan Granule for treating post ischemic stroke depression[J]. Chin Tradit Herb Drugs, 2016, 47(21): 3866-3870. https://www.cnki.com.cn/Article/CJFDTOTAL-ZCYO201621023.htm
|
[7] |
刘元月. 柴胡加龙骨牡蛎汤治疗抑郁症的临床和实验研究[D]. 南京: 南京中医药大学, 2020.
LIU YY. Clinical and experimental study on treatment of depression with Chaihu Plus Longgu Muli Decoction[D]. Nanjing: Nanjing University of Chinese Medicine, 2020.
|
[8] |
盛蕾, 刘元月, 胡丹, 等. 柴胡疏肝散治疗卒中后抑郁的网络药理学研究[J]. 中草药, 2018, 49(15): 3509-3515. https://www.cnki.com.cn/Article/CJFDTOTAL-ZCYO201815007.htm
SHENG L, LIU YY, HU D, et al. Network pharmacology of Chaihu Shugan Powder for treating post-stroke depression[J]. Chin Tradit Herb Drugs, 2018, 49(15): 3509-3515. https://www.cnki.com.cn/Article/CJFDTOTAL-ZCYO201815007.htm
|
[9] |
徐磊, 张丽萍, 宋瑞雯, 等. 加味温胆汤对抑郁模型大鼠小胶质细胞炎症反应的抑制作用及机制研究[J]. 中华中医药杂志, 2021, 36(7): 3832-3837. https://www.cnki.com.cn/Article/CJFDTOTAL-BXYY202107015.htm
XU L, ZHANG LP, SONG RW, et al. Inhibitory effect and mechanism of Jiawei Wendan Decoction on inflammation of microglia in depressed rats[J]. China J Tradit Chin Med Pharm, 2021, 36(7): 3832-3837. https://www.cnki.com.cn/Article/CJFDTOTAL-BXYY202107015.htm
|
[10] |
胡丹, 刘元月, 盛蕾. 柴胡疏肝散对卒中后抑郁模型大鼠BDNF/TrkB信号通路和炎症指标的影响[J]. 江苏中医药, 2020, 52(8): 78-81. https://www.cnki.com.cn/Article/CJFDTOTAL-JSZY202008030.htm
HU D, LIU YY, SHENG L. Effects of Chaihu Shugan Powder on BDNF/TrkB signal pathway and inflammatory indexes in post-stroke depression model rats[J]. Jiangsu J Tradit Chin Med, 2020, 52(8): 78-81. https://www.cnki.com.cn/Article/CJFDTOTAL-JSZY202008030.htm
|
[11] |
YU CJ, WANG M, LI RY, et al. TREM2 and microglia contribute to the synaptic plasticity: From physiology to pathology[J]. Mol Neurobiol, 2023, 60(2): 512-523. https://pubmed.ncbi.nlm.nih.gov/36318443/
|
[12] |
MARINELLI S, BASILICO B, MARRONE MC, et al. Microglia-neuron crosstalk: Signaling mechanism and control of synaptic transmission[J]. Semin Cell Dev Biol, 2019, 94: 138-151.
|
[13] |
张丽凤, 余双全, 梁祚仁, 等. 五味子乙素对慢性酒精中毒大鼠海马突触相关蛋白表达的影响[J]. 中国临床药理学杂志, 2021, 37(12): 1573-1576. https://www.cnki.com.cn/Article/CJFDTOTAL-GLYZ202112026.htm
ZHANG LF, YU SQ, LIANG ZR, et al. Effect of Schisandrin B on the expressions of hippocampal synapses associated proteins in rats with chronic alcoholism[J]. Chin J Clin Pharmacol, 2021, 37(12): 1573-1576. https://www.cnki.com.cn/Article/CJFDTOTAL-GLYZ202112026.htm
|
[14] |
赵迪克, 牛君, 杜志欣, 等. 基于cAMP/PKA/CREB/BDNF信号通路探讨柴胡加龙骨牡蛎汤抗抑郁的作用机制[J]. 中国实验方剂学杂志, 2023, 29(3): 17-25.
ZHAO DK, NIU J, DU ZX, et al. Based on cAMP/PKA/CREB/BDNF signaling pathway, this paper discusses the antidepressant mechanism of Chaihu Jialonggu Muli Decoction[J]. Chin J Exp Tradit Med Formulae, 2023, 29(3): 17-25.
|
[15] |
李凡, 肖波飞, 宋敏, 等. 柴胡加龙骨牡蛎汤加减通过p38 MAPK通路改善CKD小鼠PFC突触可塑性及抑郁行为研究[J]. 南京中医药大学学报, 2021, 37(6): 878-885. doi: 10.14148/j.issn.1672-0482.2021.0878
LI F, XIAO BF, SONG M, et al. Modified Chaihu Longgu Muli Decoction improved the synaptic plasticity of PFC and alleviated the depressive symptoms in CKD mice via p38 MAPK pathway[J]. J Nanjing Univ Tradit Chin Med, 2021, 37(6): 878-885. doi: 10.14148/j.issn.1672-0482.2021.0878
|
[16] |
王叶情, 王宇红, 邹蔓姝, 等. 槲皮素及其糖苷衍生物抗抑郁作用及其机制的研究进展[J]. 中草药, 2022, 53(5): 1548-1557. https://www.cnki.com.cn/Article/CJFDTOTAL-ZCYO202205030.htm
WANG YQ, WANG YH, ZOU MS, et al. Research progress on antidepressant effect and mechanism of quercetin and its glycoside derivatives[J]. Chin Tradit Herb Drugs, 2022, 53(5): 1548-1557. https://www.cnki.com.cn/Article/CJFDTOTAL-ZCYO202205030.htm
|
[17] |
ZHAO XY, KONG DW, ZHOU QM, et al. Baicalein alleviates depression-like behavior in rotenone-induced Parkinson's disease model in mice through activating the BDNF/TrkB/CREB pathway[J]. Biomed Pharmacother, 2021, 140: 111556.
|
[18] |
CHEN M, ZHANG QP, ZHU JX, et al. Involvement of FGF-2 modulation in the antidepressant-like effects of liquiritin in mice[J]. Eur J Pharmacol, 2020, 881: 173297.
|