Volume 39 Issue 5
May  2023
Turn off MathJax
Article Contents
Article Navigation >  Journal of Nanjing University of traditional Chinese Medicine  > 2023  >  39(5): 495-500
CHEN Jun, YE Liang, HE Tang-tang, YANG Chen-xi, ZHAO Yu-rong, MIN Wen, DONG Jie, WANG Yi-wei. Historical Origin, Research Progress and Prospect of Calvatia Lilacina[J]. Journal of Nanjing University of traditional Chinese Medicine, 2023, 39(5): 495-500. doi: 10.14148/j.issn.1672-0482.2023.0495
Citation: CHEN Jun, YE Liang, HE Tang-tang, YANG Chen-xi, ZHAO Yu-rong, MIN Wen, DONG Jie, WANG Yi-wei. Historical Origin, Research Progress and Prospect of Calvatia Lilacina[J]. Journal of Nanjing University of traditional Chinese Medicine, 2023, 39(5): 495-500. doi: 10.14148/j.issn.1672-0482.2023.0495
shu

Historical Origin, Research Progress and Prospect of Calvatia Lilacina

doi: 10.14148/j.issn.1672-0482.2023.0495
  • 1.

    Jiangsu Provincial Engineering Research Center of TCM External Medication Development and Application, Nanjing University of Chinese Medicine, Nanjing, 210023 China

  • 2.

    School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, China

  • 3.

    School of Medicine · Holistic Integrative Medicine, Nanjing 210023, China

  • 4.

    The First Clinical Medical College, Nanjing University of Chinese Medicine, Nanjing 210023, China

  • Received Date: 2022-03-11
    Abstract
  • Lasiosphaera seu Calvatia is a traditional Chinese medicine, which has been used in clinical practice for over two thousand years. In "Chinese Pharmacopoeia", it records that the dried fruit of Lasiosphaera seu Calvatia, including Lasiosphaera fenzlii Reich, Calvatia gigantea and Calvatia Lilacina. However, in various ancient books of Chinese medicine, only Calvatia Lilacina can be utilized as medicine. In this review paper, the application history, growth condition, chemical composition and pharmaceutical functions of Calvatia Lilacina were systematically reviewed and discussed. It was concluded that Calvatia Lilacina mainly used sporangium powder to promote wound healing. The major components of Calvatia Lilacina contain sterones, inorganic elements, volatile components and polysaccharides. Many studies reported that it can promote wound healing, prevent stress gastric ulcer and alcoholic liver injury together with antitumor ability. This paper provides a comprehensive review for further research, development and utilization of Calvatia Lilacina, leading to the research prospect of its application in wound healing under the guidance of TCM theory.

     

    • FullText(HTML)
  • loading
    • References(31)
  • [1]
    毕雅琼, 王爱祥, 包海鹰, 等. 经典名方中马勃的本草考证[J]. 中国实验方剂学杂志, 29(11): 23-33. https://www.cnki.com.cn/Article/CJFDTOTAL-ZSFX202311003.htm

    BI YQ, WANG AX, BAO HY, et al. Herbal textual research on Lasiosphaera Calvatia in famous classical formulas[J]. Chin J Experim Tradit Med Formul, 29(11): 23-33. https://www.cnki.com.cn/Article/CJFDTOTAL-ZSFX202311003.htm
    [2]
    陶弘景. 名医别录: 辑校本[M]. 尚志钧, 辑校. 北京: 中国中医药出版社, 2013: 219.

    TAO HJ. Miscellaneous Records of Famous Physicians[M]. SHANG ZJ, proofread. Beijing: Chinese medicine press, 2013: 219.
    [3]
    陶弘景. 本草经集注: 辑校本[M]. 尚志钧, 尚元胜, 辑校. 北京: 人民卫生出版社, 1994: 383.

    TAO HJ. Collected Commentaries on Shen Nong's Classic of the Materia Medica[M]. SHANG ZJ, SHANG YS, proofread. Beijing: People's Medical Publishing House, 1994: 383.
    [4]
    韩保昇. 日华子本草: 辑释本[M]. 尚志钧, 辑复. 合肥: 安徽科学技术出版社, 2005: 411.

    HAN BS. Nihuazi Materia medica: Annotated version[M]. SHANG ZJ, proofread. Hefei: Anhui science & technology publishing house, 2005: 411.
    [5]
    寇宗奭. 本草衍义[M]. 北京: 中国医药科技出版社, 2018: 102.

    KOU ZS. Extension of the Materia Medica[M]. Beijing: China medical science and technology press, 2018: 102.
    [6]
    李时珍. 本草纲目[M]. 陈贵廷, 点校. 北京: 中医古籍出版社, 1994: 604.

    LI SZ. The Grand Compendium of Materia Medica[M]. CHEN GT, proofread. Beijing : Traditional Chinese medicine ancient books publishing house, 1994: 604.
    [7]
    汪昂. 本草备要[M]. 北京: 中国医药科技出版社, 2019: 73.

    WANG A. Essentials of Materia Medica[M]. Beijing: China medical science and technology press, 2019: 73.
    [8]
    吴仪洛. 本草从新[M]. 阎忠涵, 校注. 北京: 中国医药科技出版社, 2016.

    WU YL. Thoroughly Revised Materia Medica[M]. YAN ZH, proofread. Beijing: China medical science and technology press, 2016.
    [9]
    国家中医药管理局《中华本草》编委会. 中华本草[M]. 上海: 上海科学技术出版社, 1998: 609-611.

    Editorial Board of Chinese Materia Medica, State Administration of Traditional Chinese Medicine. Chinese Materia Medica[M]. Shanghai: Shanghai science and technology press, 1998: 609-611.
    [10]
    孙浩. "煨脓长肉"法指导马勃孢子粉换药治疗慢性难愈性创面的临床观察[D]. 南京: 南京中医药大学, 2021.

    SUN H. Clinical observation on the treatment of chronic refractory wounds with the guidance of "simmering pus and growing meat" method[D]. Nanjing: Nanjing University of Chinese Medicine, 2021.
    [11]
    丁永辉. 中药马勃的本草考证[J]. 中药材, 1995, 18(9): 476-478.

    DING Y. Herbological study of Mabo[J]. J Chin Med Mater, 1995, 18(9): 476-478.
    [12]
    黄雄, 崔晓艳. 《本草述钩元》释义[M]. 太原: 山西科学教育出版社, 2009: 486.

    HUANG X, CUI XY. Annotation of Delving into the Description of the Materia Medica[M]. Taiyuan: Shanxi science education press, 2009: 486.
    [13]
    宫诗林, 曹玉峰, 王淑敏. 吉林省食药用真菌马勃的资源及鉴别研究[J]. 亚太传统医药, 2013, 9(12): 49-52 https://www.cnki.com.cn/Article/CJFDTOTAL-YTCT201312023.htm

    GONG SL, CAO YF, WANG SM. Study on the variety resources and Identification of Edible and Medicinal Fungi Puffballs from Jilin Province[J]. Asia Pac Tradit Med, 2013, 9(12): 49-52. https://www.cnki.com.cn/Article/CJFDTOTAL-YTCT201312023.htm
    [14]
    穆双双, 步洪石, 胡德, 等. 紫色秃马勃的生物学特性[J]. 菌物研究, 2020, 18(1): 31-36, 42.

    MU SS, BU HS, HU D, et al. Biological characteristics of Calvatia lilacina[J]. J Fungal Res, 2020, 18(1): 31-36, 42.
    [15]
    李昂. 吉林省马勃资源及药效物质基础研究[D]. 长春: 长春中医药大学, 2018.

    LI A. Study on the resources and pharmacodynamic material basis of puffball in Jilin Province[D]. Changchun: Changchun University of Chinese Medicine, 2018.
    [16]
    KAWAHARA N, SEKITA S, SATAKE M. Steroids from Calvatia cyathiformis[J]. Phytochemistry, 1994, 37(1): 213-215. doi: 10.1016/0031-9422(94)85028-3
    [17]
    ZENG QH, SINGH R, YE Y, et al. Calvatia lilacina extracts exert anti-breast-cancer bioactivity through the apoptosis induction dependent on mitochondrial reactive oxygen species and caspase activation[J]. Nutr Cancer, 2022, 74(3): 1058-1070. doi: 10.1080/01635581.2021.1936576
    [18]
    TSAY JG, CHUNG KT, YEH CH, et al. Calvatia lilacina protein-extract induces apoptosis through glutathione depletion in human colorectal carcinoma cells[J]. J Agric Food Chem, 2009, 57(4): 1579-1588. doi: 10.1021/jf8030265
    [19]
    岳丽丹, 杜莉杰, 杨佳宁, 等. ICP-MS法测定及PCA分析不同品种马勃无机元素含量研究[J]. 亚太传统医药, 2021, 17(4): 41-46. https://www.cnki.com.cn/Article/CJFDTOTAL-YTCT202104014.htm

    YUE LD, DU LJ, YANG JN, et al. Determination and analysis of inorganic elements contents in different varieties of lasiosphaera seu Calvatia by ICP-MS and PCA[J]. Asia Pac Tradit Med, 2021, 17(4): 41-46. https://www.cnki.com.cn/Article/CJFDTOTAL-YTCT202104014.htm
    [20]
    相聪坤, 关胜江, 王巧, 等. 不同提取方法马勃中药材挥发性成分的GC-MS分析[J]. 河北医药, 2016, 38(23): 3545-3547. https://www.cnki.com.cn/Article/CJFDTOTAL-HBYZ201623006.htm

    XIANG CK, GUAN SJ, WANG Q, et al. GC-MS analysis for the volatile constituents of Lasiosphaera calvatia extracted by different extraction methods[J]. Hebei Med J, 2016, 38(23): 3545-3547. https://www.cnki.com.cn/Article/CJFDTOTAL-HBYZ201623006.htm
    [21]
    朱月, 袁树先, 李冰. 紫色秃马勃水溶性多糖对氧自由基的清除作用[J]. 安徽农业科学, 2010, 38(8): 4053-4055

    ZHU Y, YUAN SX, LI B. Scavenging effect of water-soluble polysaccharide in purple bald Mabo on oxygen free radical[J]. J Anhui Agric Sci, 2010, 38(8): 4053-4055.
    [22]
    浙江省中医管理局《张山雷医集》编委会. 张山雷医集: 上[M]. 北京: 人民卫生出版社, 1995: 329.

    Editorial Committee of Zhang Shanlei Medical Collection of Zhejiang TCM Administration. Zhang Shanlei's Medical Collection: Part 1[M]. Beijing: People's health publishing house, 1995: 329.
    [23]
    马迪. 中药马勃促大鼠皮肤成纤维细胞增殖及胶原合成的作用研究[D]. 长春: 吉林大学, 2013.

    MA D. Study on the effect of puffball on promoting the proliferation and collagen synthesis of rat skin fibroblasts[D]. Changchun: Jilin University, 2013.
    [24]
    丁晓桐, 王裔惟, 闵文, 等. 马勃孢子粉醇提物对小鼠全层皮肤缺损性创面的治疗作用考察[J]. 中国实验方剂学杂志, 2022, 28(8): 149-158. http://qikan.cqvip.com/Qikan/Article/Detail?id=7106985184

    DING XT, WANG YW, MIN W, et al. Effect of alcohol extract of spore powder of lasiosphaera Calvatia on wound healing of full-thickness skin defect in mice[J]. Chin J Exp Tradit Med Formulae, 2022, 28(8): 149-158. http://qikan.cqvip.com/Qikan/Article/Detail?id=7106985184
    [25]
    孙菊英, 郭朝晖. 十种马勃体外抑菌作用的实验研究[J]. 中药材, 1994, 17(4): 37-38. http://www.cqvip.com/qk/92883X/199404/1588443.html

    SUN JY, GUO CH. Experimental study on the in vitro antibacterial effect of ten types of lasiosphaera seu calvatia[J]. Chin Med Mat, 1994, 17 (4): 37-38. http://www.cqvip.com/qk/92883X/199404/1588443.html
    [26]
    杨爱龙, 韩雪, 于波, 等. 马勃油膏对兔大肠杆菌感染性创面NLRP3/Caspase-1炎症通路及炎症因子表达的影响[J]. 中医药导报, 2023, 29(1): 24-30. https://www.cnki.com.cn/Article/CJFDTOTAL-HNZB202301005.htm

    YANG AL, HAN X, YU B, et al. Effect of Mabo ointment(马勃油膏) on NLRP3/caspase-1 inflammatory pathway and expression of inflammatory factors in rabbits with escherichia coli infectious wound[J]. Guid J Tradit Chin Med Pharm, 2023, 29(1): 24-30. https://www.cnki.com.cn/Article/CJFDTOTAL-HNZB202301005.htm
    [27]
    HE TT, SUN PF, LIU B, et al. Puffball spores improve wound healing in a diabetic rat model[J]. Front Endocrinol (Lausanne), 2022, 13: 942549.
    [28]
    侯喆. 马勃素对SGC-7901细胞增殖抑制作用的研究[D]. 哈尔滨: 哈尔滨商业大学, 2014.

    HOU Z. Study on the inhibitory effect of calophyllotoxin on SGC-7901 cell proliferation[D]. Harbin: Harbin University of Commerce, 2014.
    [29]
    穆双双. 紫色马勃的发酵工艺、化学成分及药效学研究[D]. 长春: 长春中医药大学, 2020.

    MU SS. Study on fermentation technology, chemical constituents and pharmacodynamics of purple puffball[D]. Changchun: Changchun University of Chinese Medicine, 2020.
    [30]
    张岳, 赵天倚, 王欢, 等. 麦角甾酮对小鼠急性酒精性肝损伤及肠道菌群群落组成的影响[J]. 中国现代应用药学, 2020, 37(21): 2561-2569.

    ZHANG Y, ZHAO TY, WANG H, et al. Effects of ergosterone on acute alcoholic liver injury and gut microbiota community composition in mice[J]. Chin J Mod Appl Pharm, 2020, 37(21): 2561-2569.
    [31]
    丁晓桐, 汤清涵, 王裔惟, 等. 马勃的化学成分研究进展及其在创面修复中的应用[J]. 南京中医药大学学报, 2021, 37(4): 609-618 doi: 10.14148/j.issn.1672-0482.2021.0609

    DING XT, TANG QH, WANG YW, et al. The chemical constituents and application prospects on wound healing of lasiosphaera seu Calvatia[J]. J Nanjing Univ Tradit Chin Med, 2021, 37(4): 609-618. doi: 10.14148/j.issn.1672-0482.2021.0609
    • Relative Articles
    • Supplements(0)
    • Cited By
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Figures(2)

    Get Citation
    PDF
    XML

    Article Metrics

    Article views (338) PDF downloads(24) Cited by()
    Proportional views
    Related

    Copyright © Journal of Nanjing University of traditional Chinese Medicine

    Sponsored by：Nanjing University of traditional Chinese MedicineAddress：No.138 xianlin Avenue, Qixia District, Nanjing cityChina Pos：210023

    Tel：025-85811935Email：xb@njucm.edu.cn

    Supported by: Beijing Renhe Information Technology Co., Ltd.    

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return