Citation: | CHEN Xiao-ying, ZHOU Jing-wen, LI Tian-ci, LU Zi-yu, YE Fang. Exploration of the Complex Pathogenic Transformation Characteristics of Type 2 Diabetes Mellitus with Thyroid Nodules Comorbidity[J]. Journal of Nanjing University of traditional Chinese Medicine, 2023, 39(4): 301-305. doi: 10.14148/j.issn.1672-0482.2023.0301 |
[1] |
ZHANG HM, FENG QW, NIU YX, et al. Thyroid nodules in type 2 diabetes mellitus[J]. Curr Med Sci, 2019, 39(4): 576-581. doi: 10.1007/s11596-019-2076-5
|
[2] |
WEISS CO, VARADHAN R, PUHAN MA, et al. Multimorbidity and evidence generation[J]. J Gen Intern Med, 2014, 29(4): 653-660. doi: 10.1007/s11606-013-2660-5
|
[3] |
周仲瑛, 吴勉华, 周学平, 等. 温经典, 传师道, 重临床, 善感悟: 略论中医药理论传承与创新研究的思路与方法[J]. 南京中医药大学学报, 2019, 35(5): 503-506, 522. http://xbs.njucm.edu.cn/jnutcmns/ch/reader/view_abstract.aspx?file_no=zr20190505&flag=1
ZHOU ZY, WU MH, ZHOU XP, et al. Discuss on thought and method of inheritance and innovation of traditional Chinese medicine theory: Review of classics, inherit of Masters' experience, emphasis of clinic and elaborate thinking[J]. J Nanjing Univ Tradit Chin Med, 2019, 35(5): 503-506, 522. http://xbs.njucm.edu.cn/jnutcmns/ch/reader/view_abstract.aspx?file_no=zr20190505&flag=1
|
[4] |
叶放, 周学平, 周仲瑛. 复合病机转化论初探[J]. 中医杂志, 2010, 51(10): 869-871, 874. doi: 10.13288/j.11-2166/r.2010.10.005
YE F, ZHOU XP, ZHOU ZY. Preliminary study on the transformation theory of compound pathogenesis[J]. J Tradit Chin Med, 2010, 51(10): 869-871, 874. doi: 10.13288/j.11-2166/r.2010.10.005
|
[5] |
杜骥腾, 石岩, 杨宇峰. 消渴病因病机理论框架研究[J]. 辽宁中医杂志, 2018, 45(10): 2073-2075. doi: 10.13192/j.issn.1000-1719.2018.10.017
DU JT, SHI Y, YANG YF. Study on theoretical framework of diabetes etiology and pathogenesis[J]. Liaoning J Tradit Chin Med, 2018, 45(10): 2073-2075. doi: 10.13192/j.issn.1000-1719.2018.10.017
|
[6] |
赵林华, 姬航宇, 冀博文, 等. 葛根芩连汤治疗糖尿病理论探讨[J]. 中华中医药杂志, 2012, 27(2): 280-283. https://www.cnki.com.cn/Article/CJFDTOTAL-BXYY201202008.htm
ZHAO LH, JI HY, JI BW, et al. Exploration of Gegen Qinlian Decoction's effect on diabetes mellitus in theory[J]. China J Tradit Chin Med Pharm, 2012, 27(2): 280-283. https://www.cnki.com.cn/Article/CJFDTOTAL-BXYY201202008.htm
|
[7] |
叶天士. 临证指南医案[M]. 上海: 上海科学技术出版社, 1959: 235.
YE TS. Case Records as a Guide to Clinical Practice[M]. Shanghai: Shanghai scientific and technical publishers, 1959: 235.
|
[8] |
柳宝诒. 温热逢源[M]. 北京: 人民卫生出版社, 1959: 79.
LIU BD. Encountering the Sources of Warm-Heat Diseases[M]. Beijing: People's medical publishing house, 1959: 79.
|
[9] |
周仲瑛. 论瘀热[J]. 南京中医药大学学报, 2006, 22(5): 273-276, 331. http://xbs.njucm.edu.cn/jnutcmns/ch/reader/view_abstract.aspx?file_no=200605125&flag=1
ZHOU ZY. On stagnated heat[J]. J Nanjing Univ Tradit Chin Med, 2006, 22(5): 273-276, 331. http://xbs.njucm.edu.cn/jnutcmns/ch/reader/view_abstract.aspx?file_no=200605125&flag=1
|
[10] |
周仲瑛. 糖尿病杂谈[J]. 江西中医药, 2001, 32(2): 15-16. https://www.cnki.com.cn/Article/CJFDTOTAL-JXZY200102008.htm
ZHOU ZY. Talking about diabetes mellitus[J]. Jiangxi J Tradit Chin Med, 2001, 32(2): 15-16. https://www.cnki.com.cn/Article/CJFDTOTAL-JXZY200102008.htm
|
[11] |
陈实功. 外科正宗[M]. 天津: 天津科学技术出版社, 1993: 135.
CHEN SG. Orthodox Lineage of External Medicine[M]. Tianjin: Tianjin science and technology publisher, 1993: 135.
|
[12] |
王桂彬, 姜晓晨, 刘福栋, 等. 甲状腺结节中医辨治浅析[J]. 环球中医药, 2021, 14(9): 1630-1633. https://www.cnki.com.cn/Article/CJFDTOTAL-HQZY202109022.htm
WANG GB, JIANG XC, LIU FD, et al. Analysis on TCM differentiation and treatment of thyroid nodules[J]. Glob Tradit Chin Med, 2021, 14(9): 1630-1633. https://www.cnki.com.cn/Article/CJFDTOTAL-HQZY202109022.htm
|
[13] |
严用和. 重订严氏济生方[M]. 北京: 人民卫生出版社, 1980: 99.
YAN YH. Redefining Yan's Formulas to Aid the Living[M]. Beijing: People's medical publishing house, 1980: 99.
|
[14] |
王盼盼, 叶放. 国医大师周仲瑛教授辨治良性甲状腺结节经验[J]. 四川中医, 2021, 39(5): 12-14. https://www.cnki.com.cn/Article/CJFDTOTAL-SCZY202105005.htm
WANG PP, YE F. Professor ZHOU zhongying's experience of differentiating and treating benign thyroid nodules[J]. J Sichuan Tradit Chin Med, 2021, 39(5): 12-14. https://www.cnki.com.cn/Article/CJFDTOTAL-SCZY202105005.htm
|
[15] |
叶放, 周学平, 程海波, 等. 基于整体观理解和创新中医病机辨证新理论[J]. 南京中医药大学学报, 2017, 33(5): 436-439. http://xbs.njucm.edu.cn/jnutcmns/ch/reader/view_abstract.aspx?file_no=ZR2017_0502&flag=1
YE F, ZHOU XP, CHENG HB, et al. Understanding and innovation of new theory of TCM syndrome differentiation based on holism[J]. J Nanjing Univ Tradit Chin Med, 2017, 33(5): 436-439. http://xbs.njucm.edu.cn/jnutcmns/ch/reader/view_abstract.aspx?file_no=ZR2017_0502&flag=1
|
[16] |
黄帝内经素问[M]. 北京: 人民卫生出版社, 1963.
The Yellow Emperor's Inner Classic: Basic Questions[M]. Beijing: People's medical publishing house, 1963.
|
[17] |
周仲瑛, 周学平, 郭立中, 等. 中医病机辨证新体系的构建及临床应用[J]. 江苏中医药, 2019, 51(2): 1-4. https://www.cnki.com.cn/Article/CJFDTOTAL-JSZY201902002.htm
ZHOU ZY, ZHOU XP, GUO LZ, et al. The construction and clinical application of new system of TCM pathogenesis differentiation[J]. Jiangsu J Tradit Chin Med, 2019, 51(2): 1-4. https://www.cnki.com.cn/Article/CJFDTOTAL-JSZY201902002.htm
|
[18] |
晁梁. 周仲瑛教授从"三热"论治糖尿病的学术思想研究[D]. 南京: 南京中医药大学, 2007.
CHAO L. Academic research on professor Zhou zhongying treating diabetes mellitus with tripe-heat[D]. Nanjing: Nanjing University of Chinese Medicine, 2007.
|
[19] |
黄元御. 四圣心源[M]. 北京: 中国医药科技出版社, 2020: 44.
HUANG YY. The Indication of Classics by Four Medical Sages[M]. Beijing: China pharmaceutical science and technology publisher, 2020: 44.
|
[20] |
董晓敏, 洪海鸥, 张洪, 等. 甲状腺及乳腺良性疾病和子宫肌瘤的关联性分析[J]. 中国临床保健杂志, 2019, 22(5): 627-630. https://www.cnki.com.cn/Article/CJFDTOTAL-LZBJ201905014.htm
DONG XM, HONG HO, ZHANG H, et al. Correlation among the prevalence of benign diseases of thyroid, breast and uterine fibroids[J]. Chin J Clin Healthc, 2019, 22(5): 627-630. https://www.cnki.com.cn/Article/CJFDTOTAL-LZBJ201905014.htm
|
[21] |
范雪, 唐钰姣, 巴妍·谢开, 等. 健康体检人群超声检查乳腺结节与甲状腺结节发病率的相关性[J]. 影像研究与医学应用, 2020, 4(12): 129-131. https://www.cnki.com.cn/Article/CJFDTOTAL-YXYY202012085.htm
FAN X, TANG YJ, BAYAN XK, et al. Correlation between ultrasound examination of breast nodules and incidence of thyroid nodules in healthy people[J]. J Imaging Res Med Appl, 2020, 4(12): 129-131. https://www.cnki.com.cn/Article/CJFDTOTAL-YXYY202012085.htm
|
[22] |
徐英, 李志学, 马艳, 等. 1990-2019年中国成年人归因于2型糖尿病的癌症疾病负担研究[J]. 中国肿瘤, 2022, 31(12): 959-966.
XU Y, LI ZX, MA Y, et al. Cancer disease burden attributable to type 2 diabetes mellitus among adults in China, 1990-2019[J]. China Cancer, 2022, 31(12): 959-966.
|
[23] |
张世安, 叶放. 周仲瑛教授从肾虚肝旺病机论治疑难杂病探讨[J]. 南京中医药大学学报, 2015, 31(2): 104-107. http://xbs.njucm.edu.cn/jnutcmns/ch/reader/view_abstract.aspx?file_no=20150202&flag=1
ZHANG SA, YE F. Discussion on professor Zhou zhongying's treating of complicated diseases from the pathogenesis of kidney deficiency and liver hyperactivity[J]. J Nanjing Univ Tradit Chin Med, 2015, 31(2): 104-107. http://xbs.njucm.edu.cn/jnutcmns/ch/reader/view_abstract.aspx?file_no=20150202&flag=1
|
[24] |
张秉成. 成方便读[M]. 上海: 科技卫生出版社, 1958: 111.
ZHANG BC. Convenient Reader on Established Formulas[M]. Shanghai: Science and health publishing house, 1958: 111.
|
[25] |
赵成程, 刘孙强, 郑旭琴. 二甲双胍通过调控糖代谢抑制甲状腺结节的研究进展[J]. 南京医科大学学报(自然科学版), 2022, 42(5): 740-745. https://www.cnki.com.cn/Article/CJFDTOTAL-NJYK202205023.htm
ZHAO CC, LIU SQ, ZHENG XQ. Progress in the study of metformin inhibiting thyroid nodules by regulating glucose metabolism[J]. J Nanjing Med Univ Nat Sci, 2022, 42(5): 740-745. https://www.cnki.com.cn/Article/CJFDTOTAL-NJYK202205023.htm
|
[26] |
MARAVILLA DOMINGUEZ MA, ZERMENO GONZALEZ ML, ZAVALETA MUNIZ ER, et al. Inflammation and atherogenic markers in patients with type 2 diabetes mellitus[J]. Clin Investig Arterioscler, 2022, 34(3): 105-112.
|
[27] |
FENG F, HAN HQ, WU SQ, et al. Crosstalk between abnormal TSHR signaling activation and PTEN/PI3K in the dedifferentiation of thyroid cancer cells[J]. Front Oncol, 2021, 11: 718578.
|
[28] |
刘蕊蕊, 岳仁宋, 杨茂艺, 等. 从"痰脂膏浊-土壤变质"论胰岛素抵抗的中医实质[J]. 中医杂志, 2018, 59(19): 1699-1701. https://www.cnki.com.cn/Article/CJFDTOTAL-ZZYZ201819020.htm
LIU RR, YUE RS, YANG MY, et al. Discussion on the essence of traditional Chinese medicine for insulin resistance from the "phlegm, fat, turbid vs earth deterioration"[J]. J Tradit Chin Med, 2018, 59(19): 1699-1701. https://www.cnki.com.cn/Article/CJFDTOTAL-ZZYZ201819020.htm
|
[29] |
苏庆民, 王琦. 肥胖人痰湿型体质血脂、血糖、胰岛素及红细胞Na+-K+-ATP酶活性的检测[J]. 中国中医基础医学杂志, 1995, 1(2): 39-41. https://www.cnki.com.cn/Article/CJFDTOTAL-ZYJC201705019.htm
SU QM, WANG Q. Detection of blood lipid, blood glucose, insulin and erythrocyte Na+-K+-ATPase activity in obese people with phlegm-dampness constitution[J]. China J Basic Med Tradit Chin Med, 1995, 1(2): 39-41. https://www.cnki.com.cn/Article/CJFDTOTAL-ZYJC201705019.htm
|
[30] |
俞亚琴, 王彬. 从血瘀角度探讨Ⅱ型糖尿病胰岛素抵抗[J]. 浙江中医杂志, 2002, 37(4): 175-176. https://www.cnki.com.cn/Article/CJFDTOTAL-ZJZZ200204026.htm
YU YQ, WANG B. Discussion on insulin resistance of type Ⅱ diabetes mellitus from the perspective of blood stasis[J]. Zhejiang J Tradit Chin Med, 2002, 37(4): 175-176. https://www.cnki.com.cn/Article/CJFDTOTAL-ZJZZ200204026.htm
|
[31] |
HEIDARI Z, MASHHADI MA, NOSRATZEHI S. Insulin resistance in patients with benign thyroid nodules[J]. Arch Iran Med, 2015, 18(9): 572-576.
|
[32] |
李健, 王珩, 毕兵, 等. 血糖波动对2型糖尿病患者凝血功能的影响[J]. 中国老年学杂志, 2015, 35(18): 5139-5141. https://www.cnki.com.cn/Article/CJFDTOTAL-ZLXZ201518044.htm
LI J, WANG H, BI B, et al. Effect of blood sugar fluctuation on coagulation function in patients with type 2 diabetes mellitus[J]. Chin J Gerontol, 2015, 35(18): 5139-5141. https://www.cnki.com.cn/Article/CJFDTOTAL-ZLXZ201518044.htm
|
[33] |
YAMADA T, SATO A, NISHIMORI T, et al. Importance of hypercoagulability over hyperglycemia for vascular complication in type 2 diabetes[J]. Diabetes Res Clin Pract, 2000, 49(1): 23-31.
|
[34] |
任爽, 刘妍彤, 张杰. 痰湿现代医学本质述析[J]. 中国中医基础医学杂志, 2021, 27(9): 1515-1518. https://www.cnki.com.cn/Article/CJFDTOTAL-ZYJC202109041.htm
REN S, LIU YT, ZHANG J. Discussion on the modern medical nature of phlegm dampness[J]. J Basic Chin Med, 2021, 27(9): 1515-1518. https://www.cnki.com.cn/Article/CJFDTOTAL-ZYJC202109041.htm
|
[35] |
HOTAMISLIGIL GS, PERALDI P, BUDAVARI A, et al. IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha- and obesity-induced insulin resistance[J]. Science, 1996, 271(5249): 665-668.
|
[36] |
HU FB, MEIGS JB, LI TY, et al. Inflammatory markers and risk of developing type 2 diabetes in women[J]. Diabetes, 2004, 53(3): 693-700.
|
[37] |
LIU XZ, WANG JM, JI YX, et al. Monocyte-to-high-density lipoprotein cholesterol ratio is associated with the presence and size of thyroid nodule irrespective of the gender[J]. Lipids Health Dis, 2020, 19(1): 36.
|
[38] |
张红敏, 谢春光, 陈世伟. 动脉粥样硬化、2型糖尿病等疾病发病学说中低度炎症的中医病理探讨[J]. 中医杂志, 2005, 46(2): 83-85. https://www.cnki.com.cn/Article/CJFDTOTAL-ZZYZ200502000.htm
ZHANG HM, XIE CG, CHEN SW. Study on TCM pathology of inflammation of low degree in attack theory of atherosclerosis, type Ⅱ diabetes and other diseases[J]. J Tradit Chin Med, 2005, 46(2): 83-85. https://www.cnki.com.cn/Article/CJFDTOTAL-ZZYZ200502000.htm
|
[39] |
FAHEY E, DOYLE SL. IL-1 family cytokine regulation of vascular permeability and angiogenesis[J]. Front Immunol, 2019, 10: 1426.
|
[40] |
朱震宏, 蒋晓真, 顾哲. 2型糖尿病大血管病变与血糖波动和炎症因子相关分析[J]. 实用糖尿病杂志, 2012, 8(2): 55-56. https://www.cnki.com.cn/Article/CJFDTOTAL-LNSY201202040.htm
ZHU ZH, JIANG XZ, GU Z. Correlation analysis of macroangiopathy with blood glucose fluctuation and inflammatory factors in type 2 diabetes mellitus[J]. J Pract Diabetol, 2012, 8(2): 55-56. https://www.cnki.com.cn/Article/CJFDTOTAL-LNSY201202040.htm
|
[41] |
张黎洋, 唐红. 糖尿病伴脂代谢异常患者的中医证型与炎症细胞因子的相关性研究[J]. 世界中西医结合杂志, 2022, 17(5): 954-958. https://www.cnki.com.cn/Article/CJFDTOTAL-SJZX202205022.htm
ZHANG LY, TANG H. Correlation between TCM syndromes and inflammatory cytokines in patients with diabetes and abnormal lipid metabolism[J]. World J Integr Tradit West Med, 2022, 17(5): 954-958. https://www.cnki.com.cn/Article/CJFDTOTAL-SJZX202205022.htm
|
[42] |
徐健强, 赵国军, 王燕, 等. 阿托伐他汀的抗炎作用及其机制的研究进展[J]. 中国动脉硬化杂志, 2016, 24(4): 419-423. https://www.cnki.com.cn/Article/CJFDTOTAL-KDYZ201604021.htm
XU JQ, ZHAO GJ, WANG Y, et al. Advance in the anti-inflammatory effect and mechanism of atorvastatin[J]. Chin J Arterioscler, 2016, 24(4): 419-423. https://www.cnki.com.cn/Article/CJFDTOTAL-KDYZ201604021.htm
|
[43] |
刘霁堂, 冯承飞. 钱学森中医现代化思想探究[J]. 科技管理研究, 2015, 35(22): 253-257. https://www.cnki.com.cn/Article/CJFDTOTAL-KJGL201522045.htm
LIU JT, FENG CF. Study on Qian Xuesen's Chinese medicine modernization thought[J]. Sci Technol Manag Res, 2015, 35(22): 253-257. https://www.cnki.com.cn/Article/CJFDTOTAL-KJGL201522045.htm
|