Efficacy of Thunder-Fire Moxibustion Combined with Sijunzi Decoction in the Treatment of Chronic Pharyngitis with Lung and Spleen Qi Deficiency and the Effect on the Level of Inflammatory Factors and Immune Factors

ZHANG Tian-tian; SUN Mai-qing

doi:10.14148/j.issn.1672-0482.2021.0669

Volume 37 Issue 5

Sep. 2021

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ZHANG Tian-tian, SUN Mai-qing. Efficacy of Thunder-Fire Moxibustion Combined with Sijunzi Decoction in the Treatment of Chronic Pharyngitis with Lung and Spleen Qi Deficiency and the Effect on the Level of Inflammatory Factors and Immune Factors[J]. Journal of Nanjing University of traditional Chinese Medicine, 2021, 37(5): 669-672. doi: 10.14148/j.issn.1672-0482.2021.0669

Citation:

ZHANG Tian-tian, SUN Mai-qing. Efficacy of Thunder-Fire Moxibustion Combined with Sijunzi Decoction in the Treatment of Chronic Pharyngitis with Lung and Spleen Qi Deficiency and the Effect on the Level of Inflammatory Factors and Immune Factors[J]. Journal of Nanjing University of traditional Chinese Medicine, 2021, 37(5): 669-672. doi: 10.14148/j.issn.1672-0482.2021.0669

Citation:

ZHANG Tian-tian, SUN Mai-qing. Efficacy of Thunder-Fire Moxibustion Combined with Sijunzi Decoction in the Treatment of Chronic Pharyngitis with Lung and Spleen Qi Deficiency and the Effect on the Level of Inflammatory Factors and Immune Factors[J]. Journal of Nanjing University of traditional Chinese Medicine, 2021, 37(5): 669-672. doi: 10.14148/j.issn.1672-0482.2021.0669

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Efficacy of Thunder-Fire Moxibustion Combined with Sijunzi Decoction in the Treatment of Chronic Pharyngitis with Lung and Spleen Qi Deficiency and the Effect on the Level of Inflammatory Factors and Immune Factors

doi: 10.14148/j.issn.1672-0482.2021.0669

ZHANG Tian-tian^1
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SUN Mai-qing^{2
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1.
The Second School of Clinical Medicine, Henan University of Chinese Medicine, Zhengzhou, 450002, China
2.
Henan Province Hospital of TCM, The Second Hospital Affiliated to Henan University of Chinese Medicine, Zhengzhou, 450002, China

Received Date: 2021-05-16
Available Online: 2021-12-21
Publish Date: 2021-09-10

Abstract

Abstract

OBJECTIVE To observe the efficacy of thunder-fire moxibustion combined with Sijunzi decoction in the treatment of chronic pharyngitis with lung and spleen qi deficiency and the effects on the levels of inflammatory factors and immune factors.METHODS A total of 60 patients with chronic pharyngitis of lung and spleen qi deficiency were randomly divided into observation group and control group, 30 patients in each group. The observation group was treated with thunder-fire moxibustion combined with modulated Sijunzi decoction, while the control group was given conventional western medical treatment. There were four courses of treatment, seven days per course. In addition, the levels of interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α), immunoglobulin A (IgA), immunoglobulin E (IgE), and secretory immunoglobulin A (SIgA), Chinese medicine syndrome scores and clinical efficacy were observed before and after treatment in the two groups.RESULTS After treatment, Chinese medicine syndrome scores of the two groups improved significantly (P < 0.05, P < 0.01), while the result in the observation group was better than that in the control group (P < 0.05, P < 0.01). The levels of inflammatory factor IL-6, TNF-α, and immune factor IgE decreased, while the levels of immune factor IgA and SIgA increased in the two groups (P < 0.01). However, the results in the observation group were better than those in the control group (P < 0.05, P < 0.01).CONCLUSION Thunder-fire moxibustion combined with modulated Sijunzi decoction treatment can significantly reduce the pharyngeal symptoms in patients with chronic pharyngitis with lung and spleen qi deficiency. The mechanism is related to reducing the levels of inflammatory factor IL-6, TNF-α, and immune factor IgE, increasing the levels of immune factor IgA and SIgA, enhancing systemic immunity, as well as improving the local environment.
- chronic pharyngitis,
- Lung spleen deficiency,
- thunder fire moxibustion,
- Immune factors

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Efficacy of Thunder-Fire Moxibustion Combined with Sijunzi Decoction in the Treatment of Chronic Pharyngitis with Lung and Spleen Qi Deficiency and the Effect on the Level of Inflammatory Factors and Immune Factors

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Efficacy of Thunder-Fire Moxibustion Combined with Sijunzi Decoction in the Treatment of Chronic Pharyngitis with Lung and Spleen Qi Deficiency and the Effect on the Level of Inflammatory Factors and Immune Factors

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