2006 Vol. 22, No. 1

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2006, 22(1)
[Abstract](862)
Abstract:
Metlmdology in Research of Pharmacology of Traditional Cldnese Medical Formulae
DUAN Jin.ao , LU Yin-yin , CHEN Jian-wei , DING Anwei , SUN Shi-fa , ZHU Quan , FAN Xin-sheng
2006, 22(1): 1-4.
[Abstract](927)
Abstract:
Based on common problems in the research of pharmacology of traditional Chinese medical formulae and practice and results of laboratory work,this paper presents methodology in the research by combining the advantages of Chinese medicine and Chinese pharmacology,traditional theories and modern concepts,and theoretical basis and practice.The authors also deal with the regularities of drug combination,researches in biological effects,researches in the basis of active components in prescriptions,application of new technology in the study of pharmacology of traditional Chinese medical formulae,exploration of information resources of prescriptions,etc.
2006, 22(1): 4-4.
[Abstract](795)
Abstract:
Treating Intractable Diseases with Acupuncture and Medication in Combination(2)
XIAO Shao-qing
2006, 22(1): 5-7.
[Abstract](799)
Abstract:
This paper deals with the treatment of intractable metrorrhagia and infertility with acupuncture and medication in combination.
2006, 22(1): 7-7.
[Abstract](863)
Abstract:
Cyto-membrane Immobolized Chromatography:Hypothesis,Method and Application in Traditional Chinese Medicine
ZHU Quan
2006, 22(1)
[Abstract](1015)
Abstract:
A wide variety of molecules,including bormones,drugs,neurotransmitters,growth factors,antigens,viruses,plasma lipoproteins and glycoproteins,elicit their biological effects by virtue of their binding to cellular receptor.Many of these agents,however,interact with receptor or other target on external surface of the cell imbedded in cellular plasma membrane.Although in most circumstance,we still do not know correctly which substance are responsible for the effects of Traditional Chinese Medicine,and through which mechanism it works.But based the clinical response and pharmacological experimental phenomena,we believe that most Traditional Chinese Medicine's effect come from their compnents which interact with target of the organism.It is generally that noncovalent binding of drug to the target on the cell membrane may appear to be essentially reversible.Receptor and other target extend through the cell membrane.The part of the target on the exterior of the cell surface capture the signal components of TCM to be communicated to the cell in the outside environment.So our working hypothesis has been put forward as:The cell membrane of organism could be used as a material with which effective chemicals in Traditional Chinese Medicine could bind to the target that embedded on it.That is basis of cyto-membrane immobilized chromatography and it's application in Traditional Chinese Medicine.The cyto-membrane lmmoboliged chromatography is composed of the biologic membrane immobilized part and the chromatography part,The apavts have beon separatedin our wark,both parts have their optimal situation.This may be the creational in our work.The applications of red blood cell membrane immobilized chromatography in Angelica archangelica,platelet membrane immobilized chromatography in Salviae miltiorrhizae radix and Mailuoning Injection,a formula herbal injection for blood stasis,have been analyzed.The results shown that cyto-membrane immobilized chromatography are worked,although it is a pilot job.
An Analysis of Stranguria by Considering "Kidney Deficiency" and "Damp-heat"
SUN Wei, ZHOU Dong, GAO Kun
2006, 22(1): 11-13.
[Abstract](974)
Abstract:
Stranguria is a common disease usually caused by kidney deficiency and damp-heat with a long duration.In this paper the authors try to clarify the pathogenesis of the disease,namely,"damp-heat" as the main pathological factor and "kidney deficiency" as the underlying cause.The authors also deals with the advantages and disadvantages of using Chinese medicine to treat stranguria.
On "Yin and Yang" in Treatise on Febrile Diseases
2006, 22(1): 14-15.
[Abstract](988)
Abstract:
A Study into Tongue Picture of 200 Depression Patients
2006, 22(1): 16-17.
[Abstract](1001)
Abstract:
Diseases of Immune System and Diabetes and Their Relationship to Dry Eye Syndrome
2006, 22(1): 18-20.
[Abstract](849)
Abstract:
Effect of Extract of Cordyceps Sinensis on Lipid Peroxidation of Mice with Viral MyocarditJs
LI Feng, GAO Xing-yu, RAO Bang-fu, LIU Li, CUI Lian-qun
2006, 22(1): 21-23.
[Abstract](962)
Abstract:
OBJECTIVE To understand the effect and significance of extract of Cordyceps Sinensis on mice with viral myocarditis. METHOD 100 male BALB/c mice were randomly divided into a control group,an infection group and a group treated with extract of Cordyceps Sinensis.The mice in the infection group and the group treated with extract of Cordyceps Sinensis were inoculated with Coxsackie B3 virus and were then killed seven and fourteen days respectively after the inoculation.Myocardium SOD,MDA and iNOS expressions were determined and semiquantitative scoring of the pathological changes of the heart was carried out under the optical microscope. RESULT Compared with the infection group,SOD activity and iNOS expressions in the group treated with extract of Cordyceps Sinensis increased markedly(P<0.01),MDA level decreased(P<0.01) and myocarditis was relieved.CONCLUSION Extract of Cordyceps Sinensis can alleviate lipid peroxidation of mice myocardium by increasing active antioxidase and inducing iNOS expression.
Treatment of Cervical Carcinoma with As2O3 Nanometer Microballoon Magnetism Induced Heating
ZHANG Dong-sheng, WANG Zi-hao, JIA Xiu-peng
2006, 22(1): 24-27.
[Abstract](1097)
Abstract:
OBJECTIVE To explore into the effect and mechanism of using As_2O_3 nanometer microballoon magnetism induced heating in the treatment of cervical carcinoma. METHOD Athymic mouse transplantation tumor models of human cervical carcinoma was made using SiHa cells.As_2O_3 nanometer microballoons,magnetic nanometer microballoons and As_2O_3 magnetic nanometer microballoons were then infused into the inoculation location of the tumor cells,which were then heated for 3 times with high-frequency alternating magnetic field.The experiment lasted for 45 days. RESULT Under the high-frequency alternating magnetic field,no tumor growth was detected in the As_2O_3 magnetic nanometer microballoon group,the tumor growth inhibiting rate being 99.93%,markedly higher than the As_2O_3 nanometer microballoon group(85.20%,P<0.01) and the magnetic nanometer microballoon group(87.72%,P<0.01).No marked differences were detected between the experimental groups and the control group in serum AST,ALT,Bun and Cr(P>0.05).No marked lesion was found in the tissue around the tumors and internal organs.CONCLUSION Under the high-frequency alternating magnetic field,As_2O_3 nanometer microballoons, magnetic nanometer microballoons and As_2O_3 magnetic nanometer microballoons are all effective in treating cervical carcinoma,especially As_2O_3 magnetic nanometer microballoons.As_2O_3 magnetic nanometer microballoons used in combination with fluid thermotherapy has dual anti-cancer effect.
Effect of Liuwei Dihuang Decoction on Blood Lipid and Fiber Dissolution Activity of Aging Rat Models with Blood Stasis
BIAN Hui-min, GONG Jie-ning, WEI Kai-feng, LIU Xue-feng, YU Jing-hua
2006, 22(1): 28-30.
[Abstract](1095)
Abstract:
OBJECTIVE To investigate into the effect of Liuwei Dihuang Decoction and its drug combination on blood lipid and fiber dissolution activity based on experiments on aging rat models with blood stasis. METHOD Using aging rat models with blood stasis,the authors made observations on the effect of Liuwei Zihuang Decoction and its drug combination on rat in vitro thrombosis,serum lipid,brinase,tissue plasminogen activator(t-PA) and plasminogen activator inhibitor(PAI). RESULT Liuwei Dihuang Decoction could inhibit rat in vitro embolism,reduce blood lipid and brinase content,decrease PAI secretion and increase the level of t-PA.CONCLUSION By regulating the secretion function of the endothelium cell of the rat models,Liuwei Dihuang Decoction can regulate blood lipid and the fibrinolytic system,thus inhibiting the formation of thrombus.
2006, 22(1): 30-30.
[Abstract](773)
Abstract:
High- fructose Diet Inducing Experimental Insulin Resistance Syndrome in Making Rat Models
CHENG Hai-bo, SI Xiao-chen, SHANG Wen-bin, BIAN Hui-min
2006, 22(1): 31-34.
[Abstract](1007)
Abstract:
Protecting Effect of Total lridoid Glycoside in Fructus Corni Officinalis on Experimental Diabetes Models with Heart Disease
SHI Yon, XU Hui-qin
2006, 22(1): 35-37.
[Abstract](1062)
Abstract:
OBJECTIVE To investigate into the protecting effect of total iridoid glycoside in Fructus Corni Officinalis on experimental diabetes models with heart disease. METHOD Models were made with high-fat diet and STZ injection.Two weeks later,Jiangtang Tongmai Capsule(0.8 g/kg) and ICO(0.05,0.1,0.2 g/kg) were used in the treatment for 16 weeks. RESULT In the model group,fasting blood sugar of the rats increased,the levels of serum NO and NOS decreased,plasma ET level rose markedly,heart indexes increased(P<0.05,P<0.01),overgrowth of the heart muscle occurred as revealed by optical microscope,varying degrees of matrix edema and tissue cell hyperplasia appeared,and there were mild inflammation and fibrosis in the endocardium and pericardium.After the application of ICO and Jiangtang Tongmai Capsule,the symptoms were relieved.CONCLUSION [WT5"BZ] ICO has certain protecting effect on diabetes with heart disease.
Effect of Alligator Altemanthera Extract on Chemical Liver Lesion
WU Qian-hu, FAN Yi-qiao, HONG Min, ZHU Quan, SHENG Jian-hui, GONG Yu-hua
2006, 22(1)
[Abstract](930)
Abstract:
OBJECTIVE To observe the effect of Alligator Alternanthera extract on mice with chemical liver lesion. METHOD Chemical liver lesion models were made and ALT,AST,MDA and SOD activity determined. RESULT Serum ALT and AST levels of the mouse models were markedly higher than those in the control group(P<0.01),SOD activity was lower than that in the control group(P<0.01) and MDA content was higher than that in the control group(P<0.01),indicating successful model creation.Serum ALT and AST activity in high and medium dosage groups decreased markedly(P<0.01),MDA content dropped markedly and SOD activity increased greatly(P<0.01).Pathohistological observation indicated that liver lesion was markedly alleviated.CONCLUSION Alligator Alternanthera has protecting effect on chemical liver lesion.
Membrane Isolation and Resin Used in Combination in Preparing Solid Form of Huanglian Jiedu Decoction
2006, 22(1): 42-43.
[Abstract](871)
Abstract:
Analysis and Evaluation of Triterpenic Acid and Anthoxanthin Contents in Cat''''s-foot Grown in Different Areas
2006, 22(1): 44-46.
[Abstract](929)
Abstract:
Chemical Recognition of HPLC Fingerprint Chromatography of Radix et Rhizoma Rhei
2006, 22(1)
[Abstract](985)
Abstract:
Determination of Concentration of Hydroxycamptothecin in Rabbit Plasma with HPLC Fluorometric Method
ZHANG Hai-xia, FANG Yun, TAN Heng-shan, ZHANG Jing-jing
2006, 22(1): 50-52.
[Abstract](947)
Abstract:
2006, 22(1): 52-52.
[Abstract](747)
Abstract:
Clinical Observation on Treatment of 25 Cases of Ear Herpes Zoster with Chinese Medicine Combined with Western Medicine
2006, 22(1): 53-54.
[Abstract](871)
Abstract:
Clinical Experience in Treatment of Chronic Hepatitis B with "Longchai Decoction"
LIU Qi-zhi
2006, 22(1): 55-57.
[Abstract](843)
Abstract:
Longchai Decoction is an empirical prescription developed by Professor IN Shi,doctoral advisor of Nanjing University of Traditional Chinese Medicine and famous TCM physician of Jiangsu.In this paper,the author deals with the practical value of Longchai Decoction and personal experience by explaining the meanings of the prescription in the treatment of chronic hepatitis B and methods of its application.
2006, 22(1): 57-57.
[Abstract](747)
Abstract:
Treatment of 72 Cases of Protrusion of Lumbar Intervertebral Disc with Electric Acupuncture and Traction
SUN Hong
2006, 22(1): 58-60.
[Abstract](837)
Abstract:
Pharmacodynamic Study of Effect of Rhinitis Spray on Rat Models with Allergic Rhinitis
YUAN Ying, GUO Xin, PAN Ying-yi
2006, 22(1): 61-63.
[Abstract](1131)
Abstract:
OBJECTIVE To explore into the pharmacodynamic effect of rhinitis spray on rat models with allergic rhinitis. METHOD Allergic rhinitis rat models were made using 10% TDI olive oil,which were then treated with rhinitis spray made from Chinese medicine,compared with a control group treated with Livostin nose spray. RESULT The rhinitis spray made from Chinese medicine could effectively inhibit the pathological changes of nose membrane of rats with allergic rhinitis and reduce the content of thylamine in the nose membrane.CONCLUSION The rhinitis spray made from Chinese medicine has good effect in inhibiting or removing the symptoms of allergic rhinitis.
2006, 22(1): 63-63.
[Abstract](808)
Abstract:
Advancement in Research of Theory of Qi-conducting
ZHENG Xiao-hong
2006, 22(1): 64-66.
[Abstract](915)
Abstract:
Recent Development in Treatment of Lipoma with Chinese Medicine
SUN Dong-hong
2006, 22(1): 67-68.
[Abstract](922)
Abstract:

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