紫色马勃的应用历史、研究概述与展望

陈军; 叶亮; 贺唐唐; 杨晨茜; 赵玉荣; 闵文; 董洁; 王裔惟

doi:10.14148/j.issn.1672-0482.2023.0495

紫色马勃的应用历史、研究概述与展望

doi: 10.14148/j.issn.1672-0482.2023.0495

陈军^{1, 2, ,},
叶亮¹,
贺唐唐^{1, 2},
杨晨茜^{1, 3},
赵玉荣^{1, 2},
闵文^{1, 4},
董洁^{1, 2},
王裔惟^{1, 2, ,}

1.
南京中医药大学江苏省中医外用药开发与应用工程研究中心, 江苏南京 210023
2.
南京中医药大学药学院, 江苏南京 210023
3.
南京中医药大学医学院·整合医学学院 210023
4.
南京中医药大学第一临床医学院, 江苏南京 210023

基金项目:

江苏省高校自然科学基金重大项目 22KJA360002

江苏省中医药科技发展计划面上项目 MS2022006

详细信息

通讯作者:
陈军，男, 教授, 博士生导师, 主要从事中药外用制剂的研究，E-mail: chenjun75@njucm.edu.cn

王裔惟, 女, 教授, 博士生导师, 主要从事药物制剂与组织工程研究, E-mail: yiweiwang@njucm.edu.cn

中图分类号: R285.5
计量
- 文章访问数: 323
- HTML全文浏览量: 100
- PDF下载量: 23
- 被引次数: 0
出版历程
- 收稿日期: 2022-03-11
- 发布日期: 2023-05-10

Historical Origin, Research Progress and Prospect of Calvatia Lilacina

CHEN Jun^{1, 2
, ,},
YE Liang¹,
HE Tang-tang^{1, 2},
YANG Chen-xi^{1, 3},
ZHAO Yu-rong^{1, 2},
MIN Wen^{1, 4},
DONG Jie^{1, 2},
WANG Yi-wei^{1, 2
, ,}

1.
Jiangsu Provincial Engineering Research Center of TCM External Medication Development and Application, Nanjing University of Chinese Medicine, Nanjing, 210023 China
2.
School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, China
3.
School of Medicine · Holistic Integrative Medicine, Nanjing 210023, China
4.
The First Clinical Medical College, Nanjing University of Chinese Medicine, Nanjing 210023, China

摘要

摘要: 马勃是我国传统真菌类中药,已有两千多年的应用历史。《中国药典》记载马勃包括脱皮马勃、大马勃或紫色马勃的干燥子实体,但中医古籍记载的马勃品种主要为紫色马勃。笔者系统介绍了紫色马勃的应用历史、生长情况、成分研究及药效学研究进展,总结出历史上紫色马勃主要取孢子粉应用于创面促愈。紫色马勃主要含有甾酮类成分、无机元素、挥发性成分和多糖类成分,具有创面促愈、抗肿瘤、预防应激性胃溃疡和酒精性肝损伤的药效。该文为紫色马勃的深入研究及开发利用提供了参考,并展望了其在中医药理论指导下用于创面促愈的研究前景。
- 紫色马勃 /
- 创面促愈 /
- 应用历史 /
- 活性成分 /
- 药效学
Abstract: Lasiosphaera seu Calvatia is a traditional Chinese medicine, which has been used in clinical practice for over two thousand years. In "Chinese Pharmacopoeia", it records that the dried fruit of Lasiosphaera seu Calvatia, including Lasiosphaera fenzlii Reich, Calvatia gigantea and Calvatia Lilacina. However, in various ancient books of Chinese medicine, only Calvatia Lilacina can be utilized as medicine. In this review paper, the application history, growth condition, chemical composition and pharmaceutical functions of Calvatia Lilacina were systematically reviewed and discussed. It was concluded that Calvatia Lilacina mainly used sporangium powder to promote wound healing. The major components of Calvatia Lilacina contain sterones, inorganic elements, volatile components and polysaccharides. Many studies reported that it can promote wound healing, prevent stress gastric ulcer and alcoholic liver injury together with antitumor ability. This paper provides a comprehensive review for further research, development and utilization of Calvatia Lilacina, leading to the research prospect of its application in wound healing under the guidance of TCM theory.
- Calvatia Lilacina /
- wound healing /
- histological record /
- active components /
- pharmaceutical capability

HTML全文

图 1 紫色马勃照片

Figure 1. Photos of Calvatia Lilacina

下载: 全尺寸图片幻灯片

图 2 紫色马勃中含有的3种麦角甾酮类成分化学结构

Figure 2. Chemical structure of three ergosterone compounds contained in Calvatia Lilacina

下载: 全尺寸图片幻灯片

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