药用动物资源学与动物药学科建设发展现状及展望

段金廒; 宿树兰; 刘睿; 郭盛; 赵明; 曹鹏; 吴啟南

doi:10.14148/j.issn.1672-0482.2022.0839

药用动物资源学与动物药学科建设发展现状及展望

doi: 10.14148/j.issn.1672-0482.2022.0839

南京中医药大学/江苏省中药资源产业化过程协同创新中心/中药资源产业化与方剂创新药物国家地方联合工程研究中心/国家中医药管理局中药资源循环利用重点研究室, 江苏南京 210023

基金项目:

国家中医药多学科交叉创新团队(道地药材生态化与资源可持续利用)支持计划 2021

江苏省动物类中药与功能肽国际合作联合实验室 2022

中央本级重大增减支项目 2060302

详细信息

作者简介:
段金廒，教授,博士研究生导师,国际欧亚科学院院士。全国中医药杰出贡献奖获得者、全国优秀科技工作者，入选全国首届“岐黄学者”中医药领军人才工程，享受国务院政府特殊津贴。现任中药资源产业化与方剂创新药物国家地方联合工程中心主任、国家中医药管理局中药资源循环利用重点研究室主任、江苏省中药资源产业化过程协同创新中心主任，兼任中国自然资源学会中药及天然药物资源研究专业委员会主任委员、中国中药协会中药资源循环利用专业委员会主任委员等。先后7次入选Elsevier中国高被引学者榜单。作为第一授奖人荣获国家科技进步二等奖2项、部省级科技一等奖6项、江苏省教学成果奖二等奖1项

通讯作者:
段金廒, 男, 教授, 博士生导师，主要从事中药资源化学研究及资源循环利用研究，E-mail: dja@njucm.edu.cn

中图分类号: R282.74
计量
- 文章访问数: 522
- HTML全文浏览量: 261
- PDF下载量: 77
- 被引次数: 0
出版历程
- 收稿日期: 2022-08-15
- 网络出版日期: 2022-10-25
- 发布日期: 2022-10-10

Progress and Prospect of Discipline Construction and Scientific Research of Animal Chinese Medicine Resources in China

Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, National and Local Collaborative Engineering Center of Chinese Medicinal Resources Industrialization and Formulae Innovative Medicine, Key Laboratory of Chinese Medicinal Resources Recycling Utilization, State Administration of Traditional Chinese Medicine, Nanjing University of Chinese Medicine, Nanjing 210023, China

摘要

摘要: 动物类中药资源是中药资源的重要组成部分, 在我国有着悠久的应用历史, 且具有独特的生物活性。作为中药资源学的分支学科, 药用动物资源学科建设目前尚处于发展阶段, 亟需加强建设力度, 不断完善学科体系。动物类中药领域的科学研究主要涉及药用动物资源调查、药用动物规范化养殖及质量标准体系、珍稀濒危药用动物新资源寻找与替代等方面。在以往研究成果的归纳整理分析基础上, 提出药用动物资源学学科建设及科学研究进一步研究方向, 以期为动物类中药资源领域的学科建设、人才培养、科学研究、社会服务及产业发展提供借鉴, 为我国动物类中药事业和产业高质量发展提供支撑。
- 动物类中药 /
- 药用动物资源 /
- 学科建设 /
- 科技创新 /
- 资源替代
Abstract: Animal TCM resources are an important part of TCM resources, which have a long history of application in China and have unique biological activities. As a branch discipline of traditional Chinese medicine resources, the discipline construction of medicinal animal resources is still in the development stage, and it is urgent to strengthen the construction efforts and constantly improve the discipline system. The scientific research in the field of animal traditional Chinese medicine mainly involves the investigation of medicinal animal resources, the standardized breeding and quality standard system, the utilization and protection of animal research resources, and the search and replacement of new resources of rare and endangered medicinal animals. Based on the induction and analysis of the previous research results, the further research and development direction of animal TCM is proposed, in order to provide reference for the discipline construction, personnel training, scientific research, social service and industrial development in the field of animal TCM resources, and to provide support for the high-quality development of animal TCM industry and industry in China.
- animal traditional Chinese medicine /
- medicinal animal resources /
- discipline construction /
- scientific and technological innovation /
- resource substitution

HTML全文

图 1 构建药用动物资源学科体系示意图

Figure 1. Diagram of constructing the discipline system of medicinal animal resources

下载: 全尺寸图片幻灯片

参考文献(56)

[1]	中国药材公司. 中国中药资源志要[M]. 北京: 科学出版社, 1994. China Medicinal Materials Corporation. Summary of Chinese traditional medicine resources[M]. Beijing: Science press, 1994.
[2]	赵润怀, 贾海彬, 周永红, 等. 我国动物药资源供给现状及可持续发展的思考[J]. 中国现代中药, 2020, 22(6): 835-839. ZHAO RH, JIA HB, ZHOU YH, et al. Combination of protection and development is the way to solve the dilemma of sustainable utilization of animal medicine[J]. Mod Chin Med, 2020, 22(6): 835-839.
[3]	童芯锌, 候飞侠, 赵美莲, 等. 《药用动物学》课程思政的探索与实践[J]. 中药与临床, 2021, 12(6): 78-81. TONG XX, HOU FX, ZHAO ML, et al. The exploration and practice of coordinating Ideological and political education with the course of Pharmaceutical Zoology[J]. Pharm Clin Chin Mater Med, 2021, 12(6): 78-81.
[4]	邓明鲁, 曲晓波, 张辉, 等. 动物药的特点及长春中医药大学在动物药工作中取得的主要成就[J]. 长春中医药大学学报, 2008, 24(5): 489-491. DENG ML, QU XB, ZHANG H, et al. Characteristics of animal medicine and the main achievements of Changchun university of traditional Chinese medicine in animal medicine work[J]. J Changchun Univ Tradit Chin Med, 2008, 24(5): 489-491.
[5]	刘睿, 赵明, 段金廒. 基于"蛋白质/肽组学-修饰组学"研究动物药功效物质基础的思路与方法[J]. 药学学报, 2020, 55(8): 1735-1743. LIU R, ZHAO M, DUAN JA. Ideas and strategies for investigating the bioactive constituents of animal derived traditional Chinese medicines based on integrated "proteomics/peptidomics-modifications" methods[J]. Acta Pharm Sin, 2020, 55(8): 1735-1743.
[6]	刘睿, 朱振华, 吴佳, 等. 羚羊角与山羊角蛋白质类成分比较研究[J]. 中国中药杂志, 2018, 43(16): 3329-3334. LIU R, ZHU ZH, WU J, et al. Comparative study on protein components of antelope horn and goat horn[J]. China J Chin Mater Med, 2018, 43(16): 3329-3334.
[7]	卢熀兴, 李友宾, 彭蕴茹, 等. 羚羊角解热抗惊厥作用研究[J]. 中药药理与临床, 2007, 23(3): 56-58. LU WX, LI YB, PENG YR, et al. Studies on antipyretic and anticonvulsant effects of Cornu antelope[J]. Pharmacol Clin Chin Mater Med, 2007, 23(3): 56-58.
[8]	王斐, 段金廒, 钱大玮, 等. 犀角及羚羊角替代资源的寻找与评价研究(Ⅱ)[J]. 南京中医药大学学报, 2007, 23(1): 36-39. WANG F, DUAN JA, QIAN DW, et al. Searching for substitutes for Cornu rhinoceri asiatici and Cornu saigae tataricae and evaluation(Ⅱ)[J]. J Nanjing Univ Tradit Chin Med, 2007, 23(1): 36-39.
[9]	王斐, 段金廒, 钱大玮, 等. 犀角及羚羊角替代资源的寻找与评价研究(Ⅰ)[J]. 南京中医药大学学报, 2005, 21(3): 163-165. WANG F, DUAN JA, QIAN DW, et al. Searching for substitutes for Cornu rhinoceri asiatici and Cornu saigae tataricae and evaluation(Ⅰ)[J]. J Nanjing Univ Tradit Chin Med, 2005, 21(3): 163-165
[10]	赵晶晶, 朱悦, 武文星, 等. 牦牛角药用源流分析与资源利用现状[J/OL]. 中国现代中药, 2022: 1-14. https://doi.org/10.13313/j.issn.1673-4890.20220605001. ZHAO JJ, ZHU Y, WU WX, et al. Medicinal History and Utilization Status of Yak Horn[J/OL]. Mod Chin Med, 2022: 1-14. https://doi.org/10.13313/j.issn.1673-4890.20220605001.
[11]	赵晶晶, 刘睿, 武文星, 等. 牦牛角药用功效及物质基础研究进展与资源化利用展望[J/OL]. 中国现代中药, 2022: 1-8. https://doi.org/10.13313/j.issn.1673-4890.20220607009. ZHAO JJ, LIU R, WU WX, et al. Research progress on medicinal efficacy and material basis of Yak horn and prospect of its resource utilization[J/OL]. Mod Chin Med, 2022: 1-8. https://doi.org/10.13313/j.issn.1673-4890.20220607009.
[12]	刘睿, 赵明, 刘晓, 等. 超高效液相色谱-串联质谱法检测水牛角特征肽[J]. 中国中药杂志, 2022, 47(5): 1279-1285. LIU R, ZHAO M, LIU X, et al. Identification of specific peptides from Bubali Cornu by ultra-performance liquid chromatography-tandem mass spectrometry[J]. China J Chin Mater Med, 2022, 47(5): 1279-1285.
[13]	石磊, 段金廒, 王斐, 等. 牦牛角等6种角类药超细粉的镇静催眠作用研究[J]. 南京中医药大学学报, 2009, 25(5): 364-366. SHI L, DUAN JA, WANG F, et al. Study on sedative and hypnotic effects of superfine powder of six kinds of horn drugs such as yak horn[J]. J Nanjing Univ Tradit Chin Med, 2009, 25(5): 364-366.
[14]	LIU R, HUANG Q, SHAN J, et al. Metabolomics of the antipyretic effects of bubali Cornu (water buffalo horn) in rats[J]. PLoS ONE, 2016, 11(7): e0158478.
[15]	LIU R, WANG M, DUAN JA, et al. Purification and identification of three novel antioxidant peptides from Cornu Bubali (water buffalo horn)[J]. Peptides, 2010, 31(5): 786-793.
[16]	LIU R, WANG M, DUAN JA. Antipyretic and antioxidant activities of the aqueous extract of Cornu bubali (water buffalo horn)[J]. Am J Chin Med, 2010, 38(2): 293-306.
[17]	ZHU Y, LIU M, QU S, et al. Elaphuri davidiani Cornu improves depressive-like behavior in mice and increases neurotrophic factor expression in mouse primary astrocytes via cAMP and ERK-dependent pathways[J]. Front Pharmacol, 2020, 11: 593993.
[18]	ZHAI YJ, ZHU ZH, ZHU Y, et al. Characterization of collagen peptides in elaphuri davidiani Cornu aqueous extract with proliferative activity on osteoblasts using nano-liquid chromatography in tandem with orbitrap mass spectrometry[J]. Molecules, 2017, 22(1): 166.
[19]	LI FT, DUAN JA, QIAN DW, et al. Comparative analysis of nucleosides and nucleobases from different sections of Elaphuri Davidiani Cornu and Cervi Cornu by UHPLC-MS/MS[J]. J Pharm Biomed Anal, 2013, 83: 10-18.
[20]	孟雪儿, 楼倩颖, 曹程, 等. 麋角丸改善Aβ_1-42海马区注射小鼠学习与记忆能力的作用机制研究[J]. 世界科学技术-中医药现代化, 2022, 24(1): 78-87. MENG XE, LOU QY, CAO C, et al. Exploration of the mechanism of Mijiao pill in improving the learning and memory ability of Aβ_1-42 Hippocampus injection mice[J]. Mod Tradit Chin Med Mater Med World Sci Technol, 2022, 24(1): 78-87.
[21]	马宏跃, 段金廒, 周婧, 等. 基于人体等效剂量的蟾酥量-效关系探讨[J]. 中国临床药理学与治疗学, 2009, 14(6): 655-658. MA HY, DUAN JA, ZHOU J, et al. Approach on Ch'an su dosage-effect relationship based on the human equivalent dose[J]. Chin J Clin Pharmacol Ther, 2009, 14(6): 655-658.
[22]	陈星玲, 宿树兰, 刘睿, 等. 胆汁类动物药中胆汁酸化学成分和药理作用研究进展[J]. 中国中药杂志, 2021, 46(19): 4898-4906. CHEN XL, SU SL, LIU R, et al. Chemical constituents and pharmacological action of bile acids from animal: A review[J]. China J Chin Mater Med, 2021, 46(19): 4898-4906.
[23]	李友宾, 张健, 段金廒, 等. 土鳖虫与日本医蛭提取物抗凝血酶活性的比较研究[J]. 时珍国医国药, 2006, 17(3): 350-351. LI YB, ZHANG J, DUAN JA, et al. Comparative studies of anticoagulant activity of Eupolyphaga sinensis and Hirudo nipponia in vitro[J]. Lishizhen Med Mater Med Res, 2006, 17(3): 350-351.
[24]	郑天瑶, 戴新新, 宿树兰, 等. 不同产地、不同龄期蚕沙中多类型资源性化学成分的分析与评价[J]. 药物分析杂志, 2019, 39(4): 624-637. ZHENG TY, DAI XX, SU SL, et al. Analysis and evaluation of multiple types of chemical constituents in silkworm excrement from different habitats and at different various instars[J]. Chin J Pharm Anal, 2019, 39(4): 624-637.
[25]	郑天瑶, 宿树兰, 蔡红蝶, 等. 基于16S rDNA测序技术分析不同龄期蚕沙中菌群多样性[J]. 中国中药杂志, 2017, 42(16): 3098-3105. ZHENG TY, SU SL, CAI HD, et al. Silkworm excrement bacterial communities diversity in different instars based on 16S rDNA sequence analysis[J]. China J Chin Mater Med, 2017, 42(16): 3098-3105.
[26]	ZHENG T, SU S, DAI X, et al. Metabolomic analysis of biochemical changes in the serum and urine of freund's adjuvant-induced arthritis in rats after treatment with silkworm excrement[J]. Molecules, 2018, 23(6): E1490.
[27]	宋百军, 王春清, 王东来. 药用动物养殖学立体化教材的建设与研究[J]. 黑龙江畜牧兽医, 2012(15): 171-173. SONG BJ, WANG CQ, WANG DL. Construction and research of three-dimensional teaching materials for medicinal animal breeding[J]. Heilongjiang Animal Sci Vet Med, 2012(15): 171-173.
[28]	宋百军, 王春清, 李长生. 药用动物养殖学精品课程理论建设与实践研究[J]. 黑龙江畜牧兽医, 2011(13): 175-177. SONG BJ, WANG CQ, LI CS. Theoretical construction and practical research on excellent course of medicinal animal breeding[J]. Heilongjiang Animal Sci Vet Med, 2011(13): 175-177.
[29]	邢济春, 宋琼章. 药用动物学实验课教学改革初探[J]. 教育教学论坛, 2015(47): 93-94. XING JC, SONG QZ. Preliminary study on teaching reform of experimental course of medicinal zoology[J]. Educ Teach Forum, 2015(47): 93-94.
[30]	叶文斌, 陈耀年, 胡文斌, 等. 甘肃省天水市药用动物资源调查[J]. 绵阳师范学院学报, 2021, 40(5): 66-74, 84. YE WB, CHEN YN, HU WB, et al. Survey of medicinal animal resources of Tianshui City in Gansu Province[J]. J Mianyang Teach Coll, 2021, 40(5): 66-74, 84.
[31]	叶文斌, 陈耀年, 胡文斌, 等. 甘肃省陇南市药用动物资源调查与评价[J]. 井冈山大学学报(自然科学版), 2021, 42(3): 37-44. YE WB, CHEN YN, HU WB, et al. Survey and evaluation of medicinal animal resources in Longnan, Gansu Province[J]. J Jinggangshan Univ Nat Sci, 2021, 42(3): 37-44.
[32]	乔永平. 平凉关山林区药用野生动物资源分布调查[J]. 西部中医药, 2014, 27(11): 80-81. QIAO YP. Investigation on the distribution of medicinal wildlife resource in Pingliang Guanshan forest region[J]. West J Tradit Chin Med, 2014, 27(11): 80-81.
[33]	廖晓雯. 广西陆生药用脊椎动物(两栖爬行及鸟类)资源调查和分析评价[D]. 南宁: 广西大学, 2014. LIAO XW. Medicine resources investigation and analysis and evaluation of terrestrial vertebrates(amphibians reptiles and birds) at Guangxi[D]. Nanning: Guangxi University, 2014.
[34]	陶睿, 崔惠生, 李丕鹏, 等. 药用两栖动物资源及对辽宁省的调查[J]. 蛇志, 2014, 26(1): 16-18. TAO R, CUI HS, LI PP, et al. Survey on medical resources of amphibians in Liaoning Province[J]. J Snake, 2014, 26(1): 16-18.
[35]	张辉, 赵润怀, 段金廒, 等. 《中国药典》2020年版药用动物养殖研究进展与对策[J/OL]. 中国现代中药, 2022: 1-16. https://doi.org/10.13313/j.issn.1673-4890.20211109004. ZHANG H, ZHAO RH, DUAN JA, et al. Research progress and countermeasures of medicinal animal breeding in Chinese Pharmacopoeia (2020 Edition)[J/OL]. Mod Chin Med, 2022: 1-16. https://doi.org/10.13313/j.issn.1673-4890.20211109004.
[36]	高旭, 赵峻露, 程端端, 等. 《中国药典》2020年版爬行纲药用动物养殖研究进展[J/OL]. 中国现代中药, 2022: 1-8. https://doi.org/10.13313/j.issn.1673-4890.20211108002. GAO X, ZHAO JL, CHENG DD, et al. Research progress on breeding of reptile medicinal animals in Chinese Pharmacopoeia[J/OL]. Mod Chin Med, 2022: 1-8. https://doi.org/10.13313/j.issn.1673-4890.20211108002.
[37]	吴淇, 尹馨雪, 兰梦, 等. 《中国药典》2020年版唇足纲和蛛形纲药用动物养殖研究进展[J/OL]. 中国现代中药, 2022: 1-6. https://kns.cnki.net/kcms/detail/11.5442.R.20220721.1639.004.html. WU Q, YIN XX, LAN M, et al. Research progress on the breeding of medicinal animals of chilopoda and arachnida in the Chinese Pharmacopoeia(2020 Edition)[J/OL]. Mod Chin Med, 2022: 1-6. https://kns.cnki.net/kcms/detail/11.5442.R.20220721.1639.004.html.
[38]	尹馨雪, 吴淇, 鞠春梅, 等. 《中国药典》2020年版昆虫纲药用动物养殖研究进展[J/OL]. 中国现代中药, 2022: 1-13. https://doi.org/10.13313/j.issn.1673-4890.20211108006. YIN XX, WU Q, JU CM, et al. Research progress on the breeding of medicinal animals of Insecta in the Chinese Pharmacopoeia[J/OL]. Mod Chin Med, 2022: 1-13. https://doi.org/10.13313/j.issn.1673-4890.20211108006.
[39]	兰梦, 吴淇, 刘玲, 等. 《中国药典》2020年版两栖纲药用动物养殖研究进展[J/OL]. 中国现代中药, 2022: 1-8. https://doi.org/10.13313/j.issn.1673-4890.20211108007. LAN M, WU Q, LIU L, et al. Research progress of amphibian medicinal animal culture in Chinese Pharmacopoeia(2020 Edition)[J/OL]. Mod Chin Med, 2022: 1-8. https://doi.org/10.13313/j.issn.1673-4890.20211108007.
[40]	程端端, 高旭, 赵峻露, 等. 《中国药典》2020年版硬骨鱼纲与鸟纲药用动物养殖研究进展[J/OL]. 中国现代中药, 2022: 1-8. https://doi.org/10.13313/j.issn.1673-4890.20211109007. CHENG DD, GAO X, ZHAO JL, et al. Research progress on the breeding of medicinal animals in the osteichthyes and aves in the Chinese Pharmacopoeia (2020)[J/OL]. Mod Chin Med, 2022: 1-8. https://doi.org/10.13313/j.issn.1673-4890.20211109007.
[41]	赵峻露, 程端端, 高旭, 等. 《中国药典》2020年版哺乳纲药用动物养殖研究进展[J/OL]. 中国现代中药, 2022: 1-12. https://doi.org/10.13313/j.issn.1673-4890.20211109006. ZHAO JL, CHENG DD, GAO X, et al. Research progress in mammalian medicinal animal breeding in Chinese Pharmacopoeia (2020 Edition)[J/OL]. Mod Chin Med, 2022: 1-12. https://doi.org/10.13313/j.issn.1673-4890.20211109006.
[42]	鞠春梅, 刘玲, 尹馨雪, 等. 《中国药典》2020年版环节动物门药用动物养殖研究进展[J/OL]. 中国现代中药, 2022: 1-8. https://doi.org/10.13313/j.issn.1673-4890.20211108004. JU CM, LIU L, YIN XX, et al. Breeding of medicinal animals belonging to annelida in the Chinese Pharmacopoeia (2020 Edition)[J/OL]. Mod Chin Med, 2022: 1-8. https://doi.org/10.13313/j.issn.1673-4890.20211108004.
[43]	刘玲, 鞠春梅, 兰梦, 等. 《中国药典》2020年版软体动物门药用动物养殖研究进展[J/OL]. 中国现代中药, 2022: 1-13. https://doi.org/10.13313/j.issn.1673-4890.20211108005. LIU L, JU CM, LAN M, et al. Research progress of the breeding of medicinal molluscs in Chinese Pharmacopoeia (2020 Edition)[J/OL]. Mod Chin Med, 2022: 1-13. https://doi.org/10.13313/j.issn.1673-4890.20211108005.
[44]	万德光, 杨文宇. 基于"品种-质量-药效"相关性的中药动物药品质观[J]. 中国现代中药, 2019, 21(9): 1127-1136. WAN DG, YANG WY. A holistic and correlative view of species/varieties, quality and efficacy for animal medicines in TCM[J]. Mod Chin Med, 2019, 21(9): 1127-1136.
[45]	杨彬, 高文远, 张艳军. 基于转录组学-蛋白质组学-多肽组学整合关联分析策略的动物药蛋白多肽类成分研究思路及方法[J]. 中草药, 2019, 50(5): 1033-1038. YANG B, GAO WY, ZHANG YJ. Research ideas and methods of protein and peptides in animal medicine based on transcriptomics-proteomics-peptidomics integrated association analysis strategy[J]. Chin Tradit Herb Drugs, 2019, 50(5): 1033-1038.
[46]	王玄, 欧阳罗丹, 代春美, 等. 动物类中药质量控制的生物评价研究[J]. 中国中药杂志, 2017, 42(12): 2228-2235. WANG X, OUYANG LD, DAI CM, et al. Biological assay in quality control of animal medicines[J]. China J Chin Mater Med, 2017, 42(12): 2228-2235.
[47]	鄢丹, 韩玉梅, 骆骄阳, 等. 基于微量量热技术与化学计量学表征的角类动物药质量生物评价研究[J]. 科学通报, 2010, 55(33): 3193-3198. YAN D, HAN YM, LUO JY, et al. Biological evaluation of the quality of horny animal drugs based on microcalorimetry and chemometrics characterization[J]. Chin Sci Bull, 2010, 55(33): 3193-3198.
[48]	蒋梦彤, 黄潇正, 蔡朔, 等. 基于Label-free定量多肽组学的鹿角胶与鹿皮胶糖基化肽研究[J]. 中国中药杂志, 2021, 46(14): 3487-3493. JIANG MT, HUANG XZ, CAI S, et al. Label-free quantitative peptidomics-based analysis on glycopeptides in deerhorn gelatin and Deer-hide gelatin[J]. China J Chin Mater Med, 2021, 46(14): 3487-3493.
[49]	房蕴歌. 以蟾酥为例探讨"TOE"思路下的动物药质量控制内涵研究[D]. 天津: 天津中医药大学, 2020. FANG YG. The totality-of-evidence approach to the development of quality control of raw drug materials from animal origin, using toad venom as an example[D]. Tianjin: Tianjin University of Chinese Medicine, 2020.
[50]	李晶峰, 边学峰, 孙佳明, 等. 基于肽键热振荡理论和酶工程技术的动物药肽类化合物研究[J]. 中国现代中药, 2019, 21(9): 1147-1156. LI JF, BIAN XF, SUN JM, et al. Study on peptides of animal drugs based on thermal oscillation theory of peptide bond and enzyme engineering technology[J]. Mod Chin Med, 2019, 21(9): 1147-1156.
[51]	左甜甜, 李耀磊, 金红宇, 等. ICP-MS法测定18种动物药中重金属及有害元素的残留量及初步风险分析[J]. 药物分析杂志, 2017, 37(2): 237-242. ZUO TT, LI YL, JIN HY, et al. Determination of residues of heavy metals and harmful elements in 18 types of animal medicines by ICP-MS and preliminary risk analysis[J]. Chin J Pharm Anal, 2017, 37(2): 237-242.
[52]	段金廒, 宿树兰, 严辉, 等. 2016-2020年我国中药资源学学科建设及科学研究进展与展望[J]. 中草药, 2021, 52(17): 5151-5165. DUAN JA, SU SL, YAN H, et al. Discipline development and research progress of Chinese medicinal material resources from 2016 to 2020[J]. Chin Tradit Herb Drugs, 2021, 52(17): 5151-5165.
[53]	朱伟豪, 吕翔, 沈莉莉, 等. 珍稀动物药代用品研究策略和方法[J]. 中国中药杂志, 2022, 47(17): 4560-4564. ZHU WH, LYU X, SHEN LL, et al. Research strategies and methods for precious animal medicine substitutes[J]. China J Chin Mater Med, 2022, 47(17): 4560-4564.
[54]	周士权, 肖国香, 张超, 等. 《本草纲目》视域下的动物药资源科学认知思想及可持续发展探讨[J]. 时珍国医国药, 2021, 32(8): 2018-2021. ZHOU SQ, XIAO GX, ZHANG C, et al. Scientific cognitive thought and sustainable development of animal medicine resources from the perspective of Compendium of Materia Medica[J]. Lishizhen Med Mater Med Res, 2021, 32(8): 2018-2021.
[55]	李西林, 张彤. 传承精华守正创新: 动物类中药的应用现状分析及未来发展思考[J]. 中医药管理杂志, 2022, 30(8): 5-7. LI XL, ZHANG T. Inheriting essence and keeping innovation-Application status analysis and future development of animal traditional Chinese medicine[J]. J Tradit Chin Med Manag, 2022, 30(8): 5-7.
[56]	张辉, 孙佳明, 林喆, 等. 药用动物资源研究开发及可持续利用[J]. 中国现代中药, 2014, 16(9): 717-723. ZHANG H, SUN JM, LIN Z, et al. Research development and sustainable use of medicinal animal resources[J]. Mod Chin Med, 2014, 16(9): 717-723.