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基于自主神经昼夜节律研究长程穿戴式动态心电监测记录仪对判断阴阳平衡的价值

程双,  成汇,  程伟,  龚冠闻,  章程,  邵明月,  董艳平,  许睿,  马朝群,  江志伟,  程海波

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文章导航 > 南京中医药大学学报  > 2022 >  38(1): 64-68
程双, 成汇, 程伟, 龚冠闻, 章程, 邵明月, 董艳平, 许睿, 马朝群, 江志伟, 程海波. 基于自主神经昼夜节律研究长程穿戴式动态心电监测记录仪对判断阴阳平衡的价值[J]. 南京中医药大学学报, 2022, 38(1): 64-68. doi: 10.14148/j.issn.1672-0482.2022.0064
引用本文: 程双, 成汇, 程伟, 龚冠闻, 章程, 邵明月, 董艳平, 许睿, 马朝群, 江志伟, 程海波. 基于自主神经昼夜节律研究长程穿戴式动态心电监测记录仪对判断阴阳平衡的价值[J]. 南京中医药大学学报, 2022, 38(1): 64-68. doi: 10.14148/j.issn.1672-0482.2022.0064
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CHENG Shuang, CHENG Hui, CHENG Wei, GONG Guan-wen, ZHANG Cheng, SHAO Ming-yue, DONG Yan-ping, XU Rui, MA Chao-qun, JIANG Zhi-wei, CHENG Hai-bo. Study on the Value of Long-Term Wearable Dynamic ECG Monitor for Determining the Balance of Yin-Yang Based on Circadian Rhythm of Autonomic Nerves[J]. Journal of Nanjing University of traditional Chinese Medicine, 2022, 38(1): 64-68. doi: 10.14148/j.issn.1672-0482.2022.0064
Citation: CHENG Shuang, CHENG Hui, CHENG Wei, GONG Guan-wen, ZHANG Cheng, SHAO Ming-yue, DONG Yan-ping, XU Rui, MA Chao-qun, JIANG Zhi-wei, CHENG Hai-bo. Study on the Value of Long-Term Wearable Dynamic ECG Monitor for Determining the Balance of Yin-Yang Based on Circadian Rhythm of Autonomic Nerves[J]. Journal of Nanjing University of traditional Chinese Medicine, 2022, 38(1): 64-68. doi: 10.14148/j.issn.1672-0482.2022.0064
shu

基于自主神经昼夜节律研究长程穿戴式动态心电监测记录仪对判断阴阳平衡的价值

doi: 10.14148/j.issn.1672-0482.2022.0064
  • 1.

    南京中医药大学附属医院, 江苏 南京 210029

  • 2.

    南京中医药大学第一临床医学院, 江苏 南京 210023

基金项目: 

江苏省中医药管理局重点项目 ZD201903

江苏省研究生培养创新工程科研与实践创新计划项目 KYCX21-1710

详细信息
    作者简介:

    程双, 女, 硕士研究生, E-mail: 281348848@qq.com

    通讯作者:

    江志伟, 男, 教授, 主要从事加速康复外科、胃肠肿瘤、肿瘤营养的研究, E-mail: surgery34@163.com

    程海波, 男, 教授, 主要从事中西医结合防治肿瘤的研究, E-mail: hbcheng@njucm.edu.cn

  • 中图分类号: R256.2

Study on the Value of Long-Term Wearable Dynamic ECG Monitor for Determining the Balance of Yin-Yang Based on Circadian Rhythm of Autonomic Nerves

  • 1.

    The Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing 210029, China

  • 2.

    The First School of Clinical Medicine, Nanjing University of Chinese Medicine, Nanjing 210023, China

    摘要
  • 摘要:   目的  运用长程穿戴式动态心电监测记录仪, 通过分析自主神经的昼夜节律与阴阳的关系, 评价其作为一种判断人体阴阳平衡手段的可行性。  方法  选取健康受试者30例, 将长程穿戴式动态心电监测记录仪贴于受试者胸前, 同步心电监测, 连续佩戴48 h。分析48 h内心率变异性指标如窦性心搏RR间期标准差(SDNN)、RR间期标准差的平均值(SDNN index)、相邻心跳间期差值大于50 ms的个数占总心跳间期数的百分比(pNN50)、频域参数低频功率(LF)、高频功率(HF)、低频/高频比(LF/HF)等, 观察其昼夜节律变化, 分析与阴阳的关系。  结果  心率变异性各项指标呈现出昼夜变化, 反映人体的昼夜节律: 夜间SDNN、SDNN index、pNN50、HF均高于日间, 差异具有统计学意义(P < 0.05);LF/HF日间高于夜间, 差异具有统计学意义(P < 0.05)。  结论  长程穿戴式动态心电监测记录仪可以通过监测及分析心率变异性, 反映自主神经的动态变化, 从而判断人体阴阳的平衡关系。

     

    Abstract:   OBJECTIVE  To evaluate the feasibility of the long-term wearable dynamic ECG monitor as a mean to determine the balance of yin and yang in the human body by analyzing the relationship between the circadian rhythm of autonomic nerves and yin-yang.  METHODS  A total of 30 healthy volunteers were selected, and a long-term wearable dynamic ECG monitor was placed on their chests for 48 h to complete simultaneous monitoring. In addition, heart rate variability indicators [the standard deviation of normal-to-normal intervals (SDNN), the index of the standard deviation of normal-to-normal intervals (SDNN index), the percentage of differences exceeding 50 ms between adjacent normal number of intervals (pNN50)] and frequency domain parameters [low frequency power (LF), high frequency power (HF), low frequency/high frequency ratio (LF/HF)] were used to observe the circadian rhythm changes and analyze the relationship between yin and yang.  RESULTS  The heart rate variability indicators showed circadian variations, and reflected the circadian rhythm in the human body. SDNN, SDNN index, pNN50 and HF were higher at nighttime than at daytime, and the differences were statistically significant (P < 0.05). However, LF/HF was higher at daytime than at nighttime, and the differences were statistically significant (P < 0.05).  CONCLUSION  The long-term wearable dynamic ECG monitor can reflect the dynamic changes of autonomic nerves by monitoring and analyzing the heart rate variability, so as to evaluate the balance relationship between yin and yang in the human body.

     

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  • 图  1  1例健康受试者48 h的心率变化图

    Figure  1.  Heart rate variation of a healthy volunteer during 48 h

    下载: 全尺寸图片 幻灯片

    图  2  HRV时域指标图

    Figure  2.  HRV time domain indicatrix

    下载: 全尺寸图片 幻灯片

    图  3  HRV频域指标图

    Figure  3.  HRV frequency domain indicatrix

    下载: 全尺寸图片 幻灯片

    图  4  Poincaré散点图

    Figure  4.  Poincaré scatter diagram

    下载: 全尺寸图片 幻灯片

    表  1  48 h HRV指标比较(x±s, n=30)

    Table  1.   Comparison of HRV indicators during 48 h (x±s, n=30)

    组别 时间 SDNN/ms SDNN index/ms pNN50/% LF/ms2 HF/ms2 LF/HF
    D1 日 108.73±25.14 62.13±14.29 10.19±7.01 735.10±431.84 471.19±459.32 1.89±0.79
    夜 132.73±32.76* 87.10±35.96* 28.69±14.42* 790.25±423.79 1 510.99±1 064.74* 0.66±0.40*
    D2 日 107.20±22.67 66.70±16.09 9.89±5.95 852.16±483.27 626.05±538.09 1.84±1.07
    夜 130.23±35.34* 89.20±35.69* 30.69±15.85* 859.79±450.35 1596.50±1042.47* 0.62±0.26*
    注: 组内比较, *P < 0.05。
    下载: 导出CSV
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  • 收稿日期:  2021-06-07
  • 网络出版日期:  2022-01-19
  • 发布日期:  2022-01-15

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