茱萸颗粒对大鼠心肌细胞抗柯萨奇病毒感染的实验研究
Experimental Study on Effect of Zhuyu Granule on Rat Myocardial Cell in Fighting against CVB3 Virus Infection
-
摘要: 目的 观察茱萸颗粒对大鼠心肌细胞抗CVB3病毒感染的作用。方法 用CVB3病毒感染大鼠心肌细胞 ,观察正常心肌对照组、病毒感染组、茱萸颗粒给药组心肌细胞病理变化和心肌酶谱变化。结果 茱萸颗粒可明显降低CVB3病毒感染后心肌细胞的病理改变和心肌细胞酶的释放 ,茱萸颗粒浓度 4 .0mg/mL的给药组与病毒对照组有非常显著差别。结论 茱萸颗粒具有较强的保护心肌细胞和助心肌细胞抗CVB3病毒感染的作用Abstract: OBJECTIVE To observe the effect of Zhuyu Granule on the rat myocardial cell in fighting against CVB3 virus infection. METHOD Myocardial cells of rats infected by CVB3 virus were used to observe the pathological changes and myocardium zymogram changes. RESULT Zhuyu Granule could markedly reduce the pathological changes of the myocardial cells after infection and the release of myocardial cell enzyme. The result obtained in the group treated with Zhuyu Granule at the concentration of 4.0 mg/mL is significantly different from the virus control group. CONCLUSION Zhuyu Granule has strong effect of protecting myocardium and preventing CVB3 virus infection.
-
Key words:
- Zhuyu Granule /
- myocardial cell /
- CVB3 virus
-
[1] 杨英珍.病毒性心肌炎进展（一）[J].中国中西医结合杂志,1995,15(8):496-498,. [2] 陈奇.中药药理实验方法学[M].北京：人民卫生出版社,2000.846. [3] 张秀明 李健斋 魏明竞 等.现代临床生化检验学[M].北京：人民军医出版社,2001.896-899. [4] 宋立人.现代中药大辞典[M].北京:人民卫生出版社,1998.234. [5] 中国中医药管理局中华本草编委会.中华本草[M].上海:上海科学技术出版社,1999.6(3):137. [6] 杜平.医用实验病毒学[M].北京:人民军医出版社,1990.111. -
点击查看大图
计量
- 文章访问数: 922
- HTML全文浏览量: 3
- PDF下载量: 0
- 被引次数: 0
下载:
