文章摘要
田磊,赵昕锐,马爱霞.参麦注射液与丹参注射液治疗冠心病心绞痛的Meta分析[J].南京中医药大学学报,2019,35(6):752-756.
参麦注射液与丹参注射液治疗冠心病心绞痛的Meta分析
Meta Analysis of Treatment of Coronary Heart Disease Angina with Shenmai Injection and Danshen Injection
  
DOI:
中文关键词: 关键词:丹参注射液  参麦注射液  冠心病心绞痛  Meta分析  中药注射剂  有效性
英文关键词: Danshen injection  Shenmai injection  coronary heart disease angina  Meta analysis  traditional Chinese medicine injection  effectiveness
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作者单位
田磊,赵昕锐,马爱霞 中国药科大学国际医药商学院江苏 南京 211198 
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中文摘要:
      目的 系统评价参麦注射液和丹参注射液治疗冠心病心绞痛的效果。方法 检索美国国立图书馆Medline数据库、Cochrane Library、万方数据资源系统、中文科技期刊全文数据库(维普)及中国知网(CNKI)数据库,纳入丹参注射液(对照组)和参麦注射液(试验组)治疗冠心病心绞痛的随机对照临床试验(RCTs),根据Cochrane Handbook评价标准进行文献筛选、资料提取和质量评价,采用RevMan 5.3软件对纳入研究进行Meta分析。结果 共检索到1 211篇文献,最终纳入20篇文献研究,共计2 034例患者。Meta分析表明,与丹参注射液组相比,参麦注射液组能够显著改善冠心病心绞痛的临床症状及心电图表现(RR<\i>=1.22,95%CI<\i>:1.16~1.28,I2<\i>=0%,P<\i>=0.80),未有不良反应相关报道。结论 参麦注射液较丹参注射液治疗冠心病心绞痛的疗效更优。
英文摘要:
      OBJECTIVE To systematically evaluate the clinical effect of Danshen injection and Shenmai injection in the treatment of coronary heart disease. METHODS Searching the Cochrane Library, Wanfang data resource system, Medline database, full text Database of Chinese Sci-tech Journals (VIP) and the Database of China Knowledge Network (CNKI), all randomized controlled clinical trials of Danshen injection (control group) and Shenmai injection (experimental group) in the treatment of coronary heart disease were included. The literature screening, data extraction and quality evaluation were carried out according to Cochrane Handbook evaluation standard. RevMan 5.3 software was used to carry on the Meta analysis to the included research. RESULTS A total of 1 211 articles were searched and 20 RCTs were included in this study, involving 2 034 patients. Meta-analysis showed that Shenmai injection group significantly improved the clinical symptoms and ECG manifestations of coronary heart disease (RR<\i>=1.22, 95%CI<\i>:1.16~1.28, I2<\i>=0%, P<\i>≤0.80) compared with Danshen injection group. No adverse reactions were reported. CONCLUSION Shenmai Injection is more effective than Danshen injection in the treatment of coronary heart disease.
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