文章摘要
张媛,罗玲,陶劲.养阴填精化瘀合剂对癌症恶病质患者的临床疗效观察[J].南京中医药大学学报,2018,34(6):561-564.
养阴填精化瘀合剂对癌症恶病质患者的临床疗效观察
Clinical Effect of Yangyin Tianjing Huayu Mixture on Cancer Patients with Cachexia
  
DOI:
中文关键词: 关键词:养阴填精化瘀合剂  阴虚血瘀证  临床疗效
英文关键词: Yangyin Tianjing Huayu Mixture  yin deficiency and blood stasis syndrome  clinical effect
基金项目:
作者单位
张媛1,罗玲2,3,陶劲4* 1.重庆市中医院肾病科重庆 4000212.重庆市中医院名医馆重庆 4000213.国家中医药管理局罗玲名中医工作室重庆 4000214.重庆市中医院肿瘤科重庆 400021 
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中文摘要:
      目的 观察养阴填精化瘀合剂对癌症恶病质阴虚血瘀证的临床疗效。方法 按照单盲随机对照试验的方法,将100例晚期肿瘤患者分为2组,治疗组使用养阴填精化瘀合剂,对照组使用醋酸甲地孕酮组,2组均给予营养支持及对症处理。观察2组研究对象在中医证候积分、生活质量评分及实验室指标的变化。结果 治疗组与对照组的中医证候疗效差别具有统计学意义(P<0.05),总有效率46%,优于对照组(P<0.01)。2组研究对象的生命质量评分差值和中医证候指标积分差值具有统计学意义。在实验室检查结果方面,治疗组与对照组血红蛋白、前白蛋白及血清白蛋白等指标的差值具有统计学意义。结论 养阴填精化瘀合剂可有效提高癌症恶病质阴虚血瘀证患者的生命质量,显著改善患者的血红蛋白、前白蛋白及血清白蛋白水平。
英文摘要:
      OBJECTIVE To observe the clinical effect of Yangyin Tianjing Huayu Mixture on cancer patients with yin deficiency and blood stasis syndrome of cancer cachexia. METHODS According to the method of single blind randomized controlled trial, 100 patients with advanced tumor were individed into two groups, the treatment group was treated with Yangyin Tianjin Huayu Mixture, the control group was treated with medroxyprogesterone acetate. Both groups were given nutritional support and symptomatic treatment. The changes of TCM syndrome score, quality of life score and laboratory indexes of two groups were observed. RESULTS The difference of TCM syndrome therapeutic effect between treatment group and control group was statistically significant (P<0.05), and the total effective rate was 46%, superior to that of the control group(P<0.01). The difference of life quality score and the difference of TCM syndrome index score between the two groups were statistically significant. In terms of laboratory test results, the difference of hemoglobin, prealbumin and serum albumin between the treatment group and the control group was statistically significant. CONCLUSION Yangyin Tianjing Huayu Mixture can effectively improve the quality of life of the patients with yin deficiency blood stasis syndrome of cancer cachexia and significantly improve the level of hemoglobin, prealbumin and serum albumin.
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