文章摘要
李惠,弓娟琴.复方黄柏液治疗急性、亚急性湿疹的临床研究[J].南京中医药大学学报,2014,30(5):492-494.
复方黄柏液治疗急性、亚急性湿疹的临床研究
Clinical Study of Fufang Huangbai Liquid in Treating Acute and Sub-acute Aczema
投稿时间:2014-04-17  修订日期:2014-06-05
DOI:
中文关键词: 湿疹  急性  亚急性  复方黄柏液  临床研究
英文关键词: aczema  acute  sub-acute  Fufang Huangbai Liquid  clinical study.
基金项目:
作者单位
李惠,弓娟琴 北京协和医学院、中国医学科学院皮肤病研究所南京 
210042 
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中文摘要:
      目的 观察复方黄柏液治疗急性、亚急性湿疹的有效性及安全性。方法 采用随机对照临床研究方法,70例受试者每日2次外用复方曲安奈德乳膏前使用或不使用复方黄柏液外用湿敷,疗程2周,观察第1、2周的临床疗效和不良反应。结果 实验组临床有效率为88.9%(32/36),高于对照组67.6%(23/34),差异显著(P<0.05);治疗后1、2周实验组的主要症状、体征指标平均值明显低于对照组,组间差异显著(P<0.05)。药物的不良反应频率低,主要表现为一过性刺激反应,可短时间消退。结论 外用激素联用复方黄柏液治疗急性、亚急性湿疹安全有效。
英文摘要:
      OBJECTIVE To evaluate the efficacy and safety of Fufang Huangbai Liquid in treating acute and sub-acute aczema. METHODS 70 patients were randomly divided into experimental group and control group. Both groups were treated with compound triamcinolone acetonide cream, while experimental group were given Fufang Huangbai Liquid simultaneously for external use. Both drugs were given twice a day for two courses with two weeks in each. Clinical therapeutic effects and side effects in first and second week were observed. RESULTS Clinical efficiency was 88.9%(32/36)in experimental group, which was better than 67.6%(23/34)in the control group. There was an obvious difference between two groups(P<0.05). Compared with control group, mean value of sign index of experimental group was distinctly lower, as well as the main symptoms. There was an obvious difference between two groups(P<0.05). Lower frequency of drugs mainly manifested as transient stimulus response which can disappear in a short time. CONCLUSION Combination of steroid and glucocorticoid and Fufang Huangbai Liquid is safe and effective on treating acute and sub-acute aczema.
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