活血化瘀药在抗肿瘤及转移中的运用思考
Thinking on the Application of Blood-Activating and Stasis-Resolving Medicine in Anti-Tumor and Metastasis
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摘要: 认为血瘀存在于肿瘤全过程,与正虚并存的血瘀为肿瘤发生发展的基本病机,癌栓粘附血管内壁所形成的静态粘附,即血瘀,是肿瘤转移的核心环节,由此提出“静态粘附为动态转移之滥觞,动态转移为静态粘附之赓衍”的观点,而正虚血瘀是癌瘤传舍的根本病机,故可运用活血化瘀配合补气药以截断肿瘤传舍之势,即破除静态粘附为中药干预肿瘤预防转移的关键。而选用恰当品种,掌握使用时机,辨证配伍他药是保证疗效的重要环节。Abstract: It is believed that blood stasis exists in the whole process of tumor, and blood stasis coexisting with deficiency is the basic pathogenesis of tumor occurrence and development. The static adhesion formed by tumor thrombus adhering to the inner wall of blood vessel, namely blood stasis, is the core link of tumor metastasis. Then, it is proposed that static adhesion is the origin of dynamic metastasis and dynamic metastasis is the development of static adhesion, while healthy qi deficiency and blood stasis is the basic pathogenesis of tumor metastasis. Therefore, blood-activating and stasis-resolving medicine combined with invigorating-qi medicine can be used to cut off the trend of tumor metastasis, that is, breaking the static adhesion is the key of Chinese medicine intervention in tumor metastasis prevention. Therefore, choosing the right variety, grasping the time of use, and dialectically combining other medicine are the important links to ensure the curative effect.
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Key words:
- blood-activating and stasis-resolving /
- anti-metastasis /
- tumor /
- Chinese medicine
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