健脾化湿汤联合清肠栓对脾虚湿热型溃疡性结肠炎患者生存质量的影响
Clinical Research of the Influence of "Jianpihuashi Decoction" and Chinese Herbal Medicine "Qingchang Shuan" on the Life Quality of Spleen Deficiency and Dampness Type Patients with Ulcerative Colitis
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摘要: 目的 探讨健脾化湿汤联合清肠栓对脾虚湿热型溃疡性结肠炎(UC)患者生存质量的影响。方法 收集脾虚湿热型UC患者65例,随机分为治疗组32例,采用健脾化湿汤联合清肠栓治疗,对照组33例,采用健脾化湿汤治疗。治疗8周后,评价患者炎症性肠病生存质量问卷(IBDQ)、健康调查简表(SF-36)积分、肠镜计分和中医症状改善情况。结果 在IBDQ总分、肠道症状(B)维度、一般健康状况(GH)维度评价方面,治疗组优于对照组(P<0.05);治疗组总有效率100%,对照组总有效率83.33%,2组间比较无统计学意义(P>0.05);单项症状脓血便、腹痛、里急后重症状比较,治疗组优于对照组(P<0.05)。肠道黏膜Baron评分,2组间比较无统计学意义(P>0.05)。结论 健脾化湿汤联合清肠栓的内外合治法能有效改善脾虚湿热型溃疡性结肠炎患者的生存质量。
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