《普济方》中咳喘相关方剂配伍规律研究
Compatible Principle of Prescriptions for Treating Cough and Asthma in Prescriptions for Universal Relief
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摘要: 目的 分析《普济方》中咳嗽、喘嗽、喘病门等肺系方剂的配伍规律。方法 搜集整理《普济方》中咳嗽、喘嗽、喘病门中的方剂,将其归类为咳嗽方、喘嗽方、哮呴方,运用关联规则对搜集到的1 036首方剂进行数据分析,得到核心药物、药对、药组。结果 咳嗽、喘嗽、哮呴三类方剂中除了其各自独有的高频药物外,支持度在10%以上的共有药物有杏仁、半夏、紫菀、款冬花、贝母、甘草、白蜜、生姜、桑白皮、五味子;在药物配伍时,三者均有杏仁-甘草-生姜、半夏-甘草-生姜、杏仁-甘草-麻黄等配伍。结论 《普济方》在治疗咳嗽、喘嗽、哮呴时,除了其共有的治法外,其中咳嗽、喘嗽的治疗偏重于扶正益气、健脾除湿,并且在喘嗽的治疗过程中更强调宣降肺气、泻肺平喘之法,而哮呴则强调了祛邪定喘,是急则治标的治则体现。Abstract: OBJECTIVE To analyze the compatible principle of lung system prescriptions for treating cough, pant-cough and asthma in Prescriptions for Universal Relief. MRTHODS The prescriptions applied for treating cough, pant-cough and asthma in Prescriptions for Universal Relief were collected and classified into cough formula, pant-cough formula and asthma formula. Association rules were used to process and analyze the selected 1 036 formulas, with the core herbs, herbal pairs and herbal groups being obtained. Then their corresponding properties and tastes were further analyzed. RESULTS Among the above three groups, apart from their own unique high frequently used herbs, the herbs like almond, pinellia ternata, aster, flos farfarae, fritillaria, licorice root, whitish honey, fresh ginger, white mulberry root-bark and the fruit of Chinese magnoliavine appeared as the commonly applied herbs with over 10% of support rate. In terms of drug compatibility, such medicine pairs as almond- licorice root-fresh ginger, pinellia ternata-licorice root-fresh ginger and almond- licorice root-ephedra can be seen in each formula. CONCLUSION Prescriptions for Universal Relief focuses much on tonification of healthy qi, invigoration of spleen and removal of dampness in treating cough and pant-cough, and especially on dispersing and descending of lung qi, purging lung and relieving asthma when dealing with pant-cough, while it attaches great importance to pathogen removal and stopping asthma for treating asthma, all of which demonstrates the treatment principle of treating secondary symptoms for emergency.
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Key words:
- Prescriptions for Universal Relief /
- cough /
- asthma /
- pant /
- data mining
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