蒲参胶囊治疗高脂血症的临床观察

于国丽; 闫慧; 胡明明; 郑方胜

蒲参胶囊治疗高脂血症的临床观察

青岛大学医学院附属医院，山东青岛 266071

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出版历程
- 收稿日期: 2013-05-11
- 修回日期: 2013-07-20
- 刊出日期: 2013-11-10

Clinical Observation of Hyperlipemia Treated by Pushen Capsule

摘要

摘要: 目的观察中成药蒲参胶囊治疗高脂血症的临床疗效，证实其调脂作用。方法将120例高脂血症患者随机分为A、B、C3组，每组40例患者，A组为蒲参胶囊组，服用蒲参胶囊，每次4粒，每日3次；B组为瑞舒伐他汀钙片组(可定组)，每晚服用可定10 mg；C组为联合治疗组，每晚服用可定10 mg，蒲参胶囊，每次4粒，每日3次，3组均在治疗6周及10周后观察调脂疗效。结果 3组治疗6周及10周后与治疗前相比，TC、TG、LDL-C均有明显下降(P<0.01)，HDL-C明显升高(P<0.01)。3组治疗10周后总有效率比较，TG总有效率A、C 2组高于B组，TC、LDL-C总有效率B、C 2组高于A组，有明显差异(P<0.05)；HDL-C总有效率3组之间无明显差异(P>0.05)。结论蒲参胶囊组对于降低TG的总有效率明显高于可定组，可定联合蒲参胶囊组对于高脂血症的疗效明显优于单用可定组或单用蒲参胶囊组，可定组对于降低TC、LDL-C的总有效率高于蒲参胶囊组。
- 蒲参胶囊 /
- 高脂血症 /
- 疗效
Abstract: OBJECTIVE To investigate the clinical effective of patent Chinese drug Pushen Capsule treating hyperlipemia， and to demonstrate its function of lipid regulation. METHODS 120 cases of hyperlipemia patients were randomly divided into 3 groups (40 cases each). Group A was the Pushen capsule group and taken Pushen capsule (4 pills of each time， three times a day); Group B was the Rosuvastatin calcium tablet group (Crestor group) taken Crestor 10mg each night; Group C was combined treatment group and taken all the drugs of the upper groups. After 6 and 10 weeks， the lipemia regulation function of each groups were investigated. RESULTS Compare with before the treatment， each groups' TC/TG/TDL-C were declined remarkably after 6 and 10 weeks treatment (P<0.01)， and HDL-C were risen prominently (P<0.01). 10 weeks total effective rate comparison shows that Groups A and C were higher than B on TG， group B and C were higher than A on TC/ LDL-C. The differences were significant (P<0.05). There was no significant difference on HDL-C in three groups (P>0.05). Adverse reactions during treatment of three groups were mild. CONCLUSION total effective rate of declining TG of Pushen capsule Group is higher than Crestor Group， and combined treatment group is more effective than Pushen capsule only or Crestor only group on treating hyperlipemia. Crestor's total effective rate is higher than Pushen capsule group on lower TC/LDL-C.
- Pushen capsule /
- hyperlipemia /
- curative effect

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参考文献(4)

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