苍耳草水溶性成分指纹图谱LC-MS/MS研究
Study on the Finger-print of Fructus Xanthii's Water-soluble Ingredients by LC-MS/MS
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摘要: 目的 研究苍耳草水溶性化学成分。方法 建立苍耳草水溶性成分的指纹图谱,通过LC-MS/MS技术鉴定其化学成分。结果 对苍耳草药材中的5种酚酸类成分的化学归属进行了指认,推测其结构为咖啡酰奎宁酸和二咖啡酰奎宁酸。结论 苍耳草中特征化学成分的识别可以显著增强其质量控制的准确性和专属性。化学成分的定性与定量相结合,可有效控制苍耳草药材及其相关产品的质量。Abstract: OBJECTIVE To study the chemical components of Fructus Xanthii's water-soluble ingredients. METHODS The finger-prints of Fructus Xanthii's water-soluble ingredients were established and the chemical components were identified by the method of LC-MS/MS. RESULTS Fructus Xanthii's five kinds of phenolic acids'chemical belonging were identified, and the structures were speculated. They are caffeoylquinic acid and dicaffeoylqcinic acid. CONCLUSION The identification of the chemical components of Fructus Xanthii can significantly enhance the accuracy and specificity of quality control. The qualitative and quantitative study of its chemical components can effectively control the quality of Fructus Xanthii and the relevant products.
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Key words:
- Fructus Xanthii /
- finger-print /
- LC-MS/MS
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