泻肝补肺针法治疗太阴人抑郁症的临床研究
Clinical Study on Needling Method of Purging Liver and Tonifying Lungs in Treating Taiyin Cases with Depression
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摘要: 目的 观察朝医泻肝补肺针法治疗太阴人抑郁症患者临床疗效,探讨其内分泌及免疫机制。方法 将符合纳入标准的太阴人抑郁症患者90例随机分为3组(治疗组、对照组、药物对照组),每组30例。治疗组采用朝医泻肝补肺针法针刺太渊、太冲穴;针刺对照组采用朝医常规针法针刺百会、内关穴;药物对照组给予西药百忧解口服。疗程8周。对比3组治疗前后HAMD抑郁量表积分,外周血皮质酮/肾上腺酮(CORT)、促肾上腺皮质激素(ACTH) 、白介素-6(IL-6)、C-反应蛋白(CRP)水平。结果 治疗后3组患者HAMD抑郁量表积分均明显降低(P<0.01),治疗组效果最佳(P<0.01);3组患者外周血CORT、ACTH水平均明显降低(P<0.01),治疗组降低最明显(P<0.05~0.01);3组患者外周血IL-6、CRP水平均明显降低(P<0.01),但3组间比较无差别。结论 泻肝补肺针法能明显降低太阴人抑郁症患者抑郁状态,优于朝医常规针法及西药百忧解,且能降低太阴人抑郁症患者外周血CORT、ACTH水平及IL-6、CRP水平。Abstract: OBJECTIVE To observe the clinical effects of needling method of purging liver and tonifying lungs in treating people of Taiyin constitution with depression and explore its endocrine and immune mechanism. METHODS Ninety cases with depression were randomly divided into 3 groups (treatment group, control group and medicine group), with 30 cases in each group. The treatment group were treated by needling method of purging liver and nourishing lungs which originated from Korean medicine, and control group were treated by acupuncture of traditional Chinese medicine around Baihui (GV 20) and Neiguan(PC 6); the medicine control group were given Proza. And the treatment last 8 weeks. Then Hamilton Depression Scale (HAMD), levels of CORT, ACTH, IL-6 and CRP in peripheral blood were compared in three groups both before and after the treatment. RESULTS After treatment, level of HAMD decreased in three groups (P<0.01), with treatment group being the best (P<0.05~0.01); and levels of CORT and ACTH decreased dramatically in all groups (P<0.01), with the treatment group being the most obvious (P<0.05~0.01); levels of IL-6 and CRP in peripheral blood reduced in all groups (P<0.01), but there was no difference between them. CONCLUSION Compared to acupuncture of traditional Chinese medicine and Proza, needling method of purging liver and tonifying lungs can greatly improve depression and is effective in reducing levels of CORT, ACTH, IL-6 and CRP in peripheral blood of Tayin people with depression.
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