养精胶囊治疗弱精子症的临床观察

金保方 黄宇烽 杨晓玉 商学军 陆晓和 王修来

养精胶囊治疗弱精子症的临床观察

金保方黄宇烽杨晓玉商学军陆晓和王修来

南京军区南京总医院男科, 南京军区南京总医院男科, 南京中医药大学第一临床医学院, 南京军区南京总医院男科, 南京军区南京总医院制剂科, 南京军区南京总医院博士后工作站江苏南京210002, 南京中医药大学第一临床医学院, 江苏南京210046, 江苏南京210002, 江苏南京210046, 江苏南京210002, 江苏南京210002, 江苏南京210002

基金项目: 2005年江苏省政府博士后科研计划基金(0501052B)，2005年江苏省政府“六大人才高峰”基金(2005A5)

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出版历程
- 收稿日期: 2006-06-03
- 修回日期: 2006-07-02
- 刊出日期: 2006-09-10

Clinical Observation on Treatment of Oligospernmtism with Yangjing Capsule

JIN Bao-fang , HUANG Yu-feng, YANG Xiao-yu, SHANG Xue-jun, LU Xiao.he, WANG Xiu-lai

1 Andrology Department of General Hospital of Nanjing Military District, Nanjing, Jhmgsu, 210001, China;2 First Clinical College of Nanjing University of Traditional Chinese Medicine, Nanjing, Jiangsu, 210029, China;3 Pharmaceutical Department of General H

摘要

摘要: 目的探讨养精胶囊治疗弱精子症的疗效与安全性。方法245例弱精子症患者随机分为治疗组195例与对照组50例,治疗组口服养精胶囊,对照组服用五子衍宗丸,治疗90天后评定疗效。结果治疗组总有效率为88.68%,对照组总有效率71.11%,2组总有效率有显著性差异(P<0.01)。治疗组治疗后前向运动精子的比例逐渐增加,与治疗前比较有显著性差异(P<0.01);对于合并少精子症,精子密度大于500万/mL,养精胶囊能增加精子密度,与治疗前比较有显著性差异(P<0.01);增加精浆果糖的含量,与治疗前比较有显著性差异(P<0.01)。2组治疗期间均无严重不良事件发生。结论养精胶囊治疗弱精子症疗效显著,对于精子密度大于500万/mL的少弱精子症,能显著增加精子密度,无严重不良反应。
- 养精胶囊 /
- 弱精子症 /
- 临床疗效
Abstract: OBJECTIVE To investigate into the effect and safety of Yangjing Capsule in the treatment of oligospermatism.METHOD 245 patients with oligospermatism were randomly divided into a treatment group of 195 patients and a control group of 50 patients,who took Yangjing Capsule and Wuzi Yanzong Pill respectively for 90 days.RESULT The effective rates of the treatment group and control group were 88.68% and 71.11% respectively,with marked difference(P<0.01).The forward motility sperm increased gradually in the treatment group after the treatment,with marked difference as compared with the sperm count before the treatment(P<0.01).For patients with oligospermatism as a complication with a sperm density of over 5,000,000/mL,Yangjing Capsule could increase the sperm density,with marked difference as compared with the sperm count before the treatment(P<0.01).Seminal plasma fructose level was also increased,with marked difference as compared with the level before the treatment.No serious undesirable accident occurred in both group.CONCLUSION Yangjing Capsule is very effective for oligospermatism and can markedly increase sperm density for patients with a sperm density of over 5,000,000/mL,with no serious side effect.
- Yangying Capsule /
- oligospermatism /
- clinical effect

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参考文献(11)

[1]	王益鑫.男性不育症诊断与治疗[M].上海:上海科学技术文献出版社,1998,203.
[2]	金保方,黄宇烽,杨晓玉,等.1 186例男性不育患者实验室检查结果及病因分析[J].南京中医药大学学报,2005,21(5):318.
[3]	张树成,王弘毅,王介东,等.1981-1996年我国有生育能力精液质量变化分析[J].生殖与避孕,1999,19(1):27.
[4]	谷诩群,陈振文,于各鸣,等译.世界卫生组织编.人类精液及精子--宫颈粘液相互作用实验室检验手册[M].第4版.北京:人民卫生出版社,2001.5.
[5]	Bayasgalan G,Naranbat D,Tsedmaa B,et al.Clinical patterns and major causes of infertility in Mongolia[J].J Obstet Gynaecol Res,2004,30(5):386.
[6]	王光荣,周曾娣,葛争鸣,等.精子凋亡与男性不育关系初探[J].中华男科学,2002,8(1):25.
[7]	史本康,武广平.男性不育症的诊断与治疗[J].山东医药,2000,40(18):48.
[8]	闫爱荣,李二军.淫羊藿的现代药理研究概述[J].中医药研究,1999,15(1):62.
[9]	高学敏.中药学[M].北京:中国中医药出版社,2002.517.
[10]	徐福松,时永华,何映,等.聚精丸治疗精液异常所致男性不育症246例[J].江苏中医,1996,17(2):21.
[11]	金保方,黄宇烽,陆晓和.养精胶囊治疗男性性功能障碍的临床观察[J].中华男科学,2006,12(3):272,276.