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针刺对抑郁症模型大鼠行为学的影响

张建斌 王玲玲 吕梅 刘兰英 利达

张建斌 王玲玲 吕梅 刘兰英 利达. 针刺对抑郁症模型大鼠行为学的影响[J]. 南京中医药大学学报, 2005, 21(1): 36-39.
引用本文: 张建斌 王玲玲 吕梅 刘兰英 利达. 针刺对抑郁症模型大鼠行为学的影响[J]. 南京中医药大学学报, 2005, 21(1): 36-39.
ZHANG Jian-bing, WANG Ling-ling, LU Mei, LIU Lan-ying, LI Da. Effect of Acupuncture in Inhibiting Behavior of Rats with Depression[J]. Journal of Nanjing University of traditional Chinese Medicine, 2005, 21(1): 36-39.
Citation: ZHANG Jian-bing, WANG Ling-ling, LU Mei, LIU Lan-ying, LI Da. Effect of Acupuncture in Inhibiting Behavior of Rats with Depression[J]. Journal of Nanjing University of traditional Chinese Medicine, 2005, 21(1): 36-39.

针刺对抑郁症模型大鼠行为学的影响

基金项目: 江苏省教育厅自然科学基金资助 (编号 :0 3KJA3 60 0 93 )

Effect of Acupuncture in Inhibiting Behavior of Rats with Depression

  • 摘要: 目的 观察针刺对抑郁症模型大鼠行为学的影响。方法 选择Open Field法评分相近的 5 0只成年SD雄性大鼠随机分为正常对照组、模型组、空白对照组、药物组、针刺组 ,每组各 10只。应用分养和长期不可预见性中等强度应激造成抑郁症模型大鼠。以Open Field法和糖水消耗实验对照研究针刺对慢性应激诱导的抑郁症模型大鼠行为学的改变。结果 与正常对照组比较 ,模型组大鼠Open Field评分降低 ,糖水消耗量减少 ;与空白对照组比较 ,各治疗组大鼠在治疗过程中Open Field评分升高 ,糖水消耗量增加 ;而针刺治疗与药物治疗在行为学评价方面无显著性差异。结论 实验结果提示针刺治疗可以改变分养和长期不可预见性中等强度应激诱导的抑郁症模型大鼠的行为学异常 ,其疗效与氟西汀相当

     

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  • 修回日期:  2004-10-21
  • 刊出日期:  2005-01-10

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