穴位埋线治疗原发性失眠的临床研究

郭爱松; 李爱红; 冯兰芳; 陈鑫; 孙丽

穴位埋线治疗原发性失眠的临床研究

南通大学附属医院，江苏南通 226001

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出版历程
- 收稿日期: 2013-01-27
- 修回日期: 2013-03-11
- 刊出日期: 2013-07-10

Clinical Study of Acupoint Catgut-Embedding Therapy on Patients with Insomnia

摘要

摘要: 目的观察穴位埋线治疗失眠症的临床疗效，并探讨其作用机制。方法 70例失眠患者随机分为针刺组（n=35）和埋线组（n=35），针刺组采用针刺治疗，主穴取神门、三阴交、百会、安眠，针刺平补平泻，留针30 min，每10 min行针1次，每日治疗1次，每周5次，连续治疗6周；埋线组采用穴位埋线治疗，埋线穴位和针刺组相同，采用一次性使用无菌埋线针和医用羊肠线埋线，每2周治疗1次，共治疗3次。用匹兹堡睡眠质量指数量表(PSQI)评定临床疗效，并用酶联免疫吸附法(ELISA)检测治疗前后血清中白细胞介素-1β(IL-1β)、肿瘤坏死因子-α(TNF-α)的含量。结果治疗6周后，针刺组有效率为74.28%，埋线组为91.43%，差异具有统计学意义(P<0.05)。2组治疗前后PSQI各因子及总分比较差异均有统计学意义(P＜0.05)，组间比较，在睡眠质量、睡眠时间、日间功能障碍及总分方面差异有统计学意义(P<0.05)，埋线组优于针刺组。2组治疗前后血清IL-1β及TNF-α含量比较差异有统计学意义(P＜0.05)，组间比较，P＜0.05。结论穴位埋线能提高失眠患者临床疗效，较好改善睡眠质量、增加睡眠时间及增强日间功能，其机理可能与穴位埋线能更好调节睡眠有关的细胞因子含量有关。
- 失眠 /
- 穴位埋线 /
- 匹兹堡睡眠质量指数 /
- 白细胞介素-1β /
- 肿瘤坏死因子-α
Abstract: OBJECTIVE To evaluate the effect of acupoint catgut-embedding on patients with insomnia and to explore its mechanism. METHODS 70 cases were randomly divided into acupuncture group (35 cases) treated with acupuncture and catgut-embedding group (35 cases) treated with acupoint-catgut-embedding. Main points were Shenmen (HT7)， Sanyinjiao (SP6)， Baihui (DU20)， Anmian. Puncturing the points with filiform needle even reinforcing and even reducing in the acupuncture group， retaining the needle for 30min and stimulating the needle once every 10min， the treatment was given once a day， five times a week for 30 times totally. Catgut embedding needle and catgut were used at the points in catgut-embedding group， once 2 weeks for 3 times totally. Effect was evaluated by Pittsburgh sleep quality index scale (PSQI)， and serum cytokine Interleukin-1β (IL-1β)， Tumor necrosis factor-α(TNF-α)were detected by Enzyme-linked immunosorbent assay (ELISA) before and after treatment. RESULTS After 6 weeks' treatment， the total effective was 74.28% in acupuncture group， and that in catgut-embedding group was 91.43% (P<0.05). Scores of the factors and total scores of PSQI in both groups after treatment were decreased compared with those before treatment (P<0.05)， however， comparisons between two groups after treatment showed that the effect of catgut-embedding group was significantly superior to acupuncture group in sleep quality， daytime dysfunction， sleep time and total scores of PSQI (P<0.05). CONCLUSION Acupoint-catgut-embedding can improve the clinical effect， especially in sleep quality， daytime dysfunction， and sleep time with little adverse effects， so it is deserved to be widely applied in clinic， which maybe mechanically related to regulation of sleep-related serum cytokine .
- insomnia /
- acupoint-catgut-embedding /
- PSQI /
- IL-1β /
- TNF-α

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